Adaptation to stroke using a model of successful aging

ABSTRACT

The process of adaptation to the physical and psychosocial consequences after stroke is a major challenge for many individuals affected. The aim of this study was to examine if stroke patients within 1 month of admission (n?=?153) and followed up at 1 year (n?=?107) engage in selection, optimization, and compensation (SOC) adaptive strategies and the relationship of these strategies with functional ability, health-related quality of life (HRQOL) and depression 1 year later. Adaptive strategies were measured using a 15-item SOC questionnaire. Internal and external resources were assessed including recovery locus of control, stroke severity, and socio-demographics. Outcome measures were the Stroke Specific Quality of Life Questionnaire (SS-QoL), the Nottingham Extended Activities of Daily Living Scale and the Depression Subscale of the Hospital Anxiety and Depression Scale. Findings indicated that stroke patients engaged in the use of SOC strategies but the use of these strategies were not predictive of HRQOL, functional ability or depression 1 year after stroke. The use of SOC strategies were not age specific and were consistent over time, with the exception of the compensation subscale. Results indicate that SOC strategies may potentially be used in response to loss regulation after stroke and that an individual's initial HRQOL functional ability, levels of depression and socio-economic status that are important factors in determining outcome 1 year after stroke. A stroke-specific measure of SOC may be warranted in order to detect significant differences in determining outcomes for a stroke population.     

Do older individuals have difficulty processing motion or excluding noise? Implications for safe driving

This study aimed to determine if difficulties extracting signal from noise explained poorer coherent motion thresholds in older individuals, particularly women. In four experimental conditions the contrast of the signal and noise dots used in a random dot kinematogram was manipulated. Coherence thresholds were highest when the signal dots were of a lower contrast than the noise dots and lowest when the signal dots were of a higher contrast than the noise dots. In all conditions the older group had higher coherence thresholds than the younger group, and women had higher thresholds than men. Significant correlations were found between coherence thresholds and self-reported driving difficulties in conditions in which the signal dots had to be extracted from noise only. The results indicate that older individuals have difficulties extracting signal from noise in cluttered visual environments. The implications for safe driving are discussed.     

Life satisfaction across adulthood: different determinants at different ages?

It is likely that with aging and changing life circumstances, individuals’ values shift in systematic ways, and that these shifts may be accompanied by shifts in the determinants of their subjective judgments of well being. To examine this possibility, the relations among the Satisfaction With Life Scale (SWLS) and a number of personality, affect, demographic, and cognitive variables were examined in a sample of 818 participants between the ages of 18 and 94. The results indicated that although many variables had significant zero-order correlations with the SWLS, only a few variables had unique utility in predicting life satisfaction. Invariance analyses indicated that while the qualitative nature of life satisfaction remains constant across adult age, the influence of fluid intelligence on judgments of life satisfaction declines with age. In contrast, negative affect is negatively associated with life satisfaction consistently across the adult age span.     

My word! Interference from reading object names implies a role for competition during picture name retrieval

A related word prime has been found to interfere with picture naming after unrelated intervening trials (word-to-picture interference). Recently, Stroop-type picture–word interference effects have been interpreted in terms of a postlexical response exclusion process rather than a competitive lexical selection process. An experiment is reported that examines whether word-to-picture effects could reflect response exclusion mechanisms and, more generally, strategic processing of the word prime. Forty-eight volunteer university students named aloud sequences of semantically related (and unrelated) word primes and picture targets, separated by two unrelated filler stimuli. On half of the trials, participants were asked to count backwards in threes from a random number presented immediately after naming the prime word. They were also given a surprise recall test at the end of the naming block. Results for naming times and errors indicated a main effect of relatedness; semantic interference effects were not dependent on the unfilled gap following the word prime trial and were also not tied to episodic recall of prime words. The data indicate that slowed picture naming times are more likely to emerge from processes intrinsic to word prime naming rather than controlled processing and do not readily fit the postlexical response exclusion account. The results are considered in relation to two recent accounts of interference over unrelated trials, which refer to some form of competition at, or prior to, lexical access.     

Solving distant analogies reduces belief-based responding in transitive inference

ABSTRACT

Previous research demonstrated that relational processing in transitive inference problems can be disrupted by belief-based content. Given the premises, The horse is larger than the goat, and The goat is larger than the elephant, accepting the valid conclusion, The horse is larger than the elephant suggests use of relational processing whereas accepting the invalid conclusion The elephant is larger than the horse indicates belief-based responding. This research examined whether solving analogies influenced participants’ reliance on belief-based or relational processing. Participants generated solutions to either distant analogies (e.g. nose:scent::antenna: ______) or near analogies (e.g. nose:scent::tongue:______) before evaluating the conclusions of transitive inference problems that were valid (V) or invalid (I) and believable (B), unbelievable (U) or neutral (N). Solving distant analogies eliminated belief-based responding (possibly reflecting improved inhibitory control) and facilitated relational responding on VU problems.     

Environmental enrichment results in cortical and subcortical changes in levels of synaptophysin and PSD-95 proteins

Experience-dependent plasticity is thought to involve selective change in pre-existing brain circuits, involving synaptic plasticity. One model for looking at experience-dependent plasticity is environmental enrichment (EE), where animals are exposed to a complex novel environment. Previous studies using electron microscopy showed that EE resulted in synaptic plasticity in the visual cortex and hippocampus. However, the areas in the brain that have been examined following EE have been limited. The present study quantified potential synaptic plasticity throughout the brains of C57BL/6 mice using an enzyme-linked immunosorbent assay (ELISA) for two synaptic proteins, synaptophysin and PSD-95. EE resulted in increased synaptophysin and PSD-95 levels through major brain regions, including anterior and posterior areas of the forebrain, hippocampus, thalamus, and hypothalamus. However, no changes in synaptophysin were detected in the cerebellum. These results demonstrate that EE results in an increase in levels of both pre- and post-synaptic proteins in multiple regions of the brain, and it is possible that such changes represent the underlying synaptic plasticity occurring in EE.     

Timing at the Start of Associative Learning

Some theories of associative learning imply that time plays a fundamental role in the acquisition process. Consistent with these theories, this paper presents evidence that the time from the onset of a conditioned stimulus (CS) until presentation of the unconditioned stimulus (US) is learned very rapidly at the start of training. We report two autoshaping studies and a study on aversive conditioning in goldfish in which we examine timing at the start of conditioning. We also review data from a number of other conditioning preparations, including fear-potentiated startle, appetitive conditioning in rats, and eyeblink conditioning in rabbits, that report conditioned response (CR) timing early in training. Acquisition speed and the very first expressions of conditioned responding often show sensitivity to the time of US presentation. In instances where temporal control is slowly expressed, it is likely due to performance factors, not to slow learning about time. In fact, the learning about time may be a necessary condition for associative learning.     

No Time of Day Modulation or Time Stamp on Multiple Memory Tasks in Rats

Various demonstrations of “time stamp” effects in the animal learning literature have reinforced the idea that circadian information is encoded as part of a combined internal/external representation of context and that this contextual information is utilized for complex retrieval processes supporting memory. The goal of the present series of experiments is to assess this idea by manipulating training/testing circadian times on a battery of learning and memory tasks commonly used in the rodent. The data obtained from five experiments using four different learning and memory paradigms provide no evidence for “time stamp” effects on place memory, context memory (aversive or appetitive), or S-R habit learning.     

Coaching

Zusammenfassung Coaching ist in Wirtschaftsunternehmen weit verbreitet. Angesichts der stetig steigenden Ver?nderungsgeschwindigkeit der Arbeits- und pers?nlichen Lebenswelten suchten zun?chst Führungskr?fte professionelle Coaches, die ihnen als vertraute Gespr?chspartner zur Seite standen. Coachingma?nahmen werden aber auch zunehmend von Politikern, Medienvertretern, Künstlern und Freiberuflern nachgefragt. Die derzeitigen Coachingkonzepte enthalten zumeist eine Kombination von allgemein-psychologischen, kognitiv-verhaltensorientierten, psychodynamischen und systemischen Techniken, modifiziert durch die Lebenserfahrung und Weltanschauung der Coaches. Es existiert eine Vielzahl eklektischer Praktiken, die theoretisch nicht koh?rent begründet und wissenschaftlich nicht verl?sslich evaluiert sind. Da Coaching in der Praxis h?ufig eine Form von Psychohygiene und Psychotherapie für Gesunde darstellt, ist es nahe liegend die Ergebnisse psychotherapeutischer Theoriebildung, Praxiserfahrung und Forschung als Grundlage des Coaching zu nutzen. Drei wissenschaftlich fundierte Aspekte des Coaching lassen sich herausstellen: Die hilfreiche Beziehung, kognitiv-verhaltensorientiertes Training und psychodynamisches Verstehen. Darüber hinaus ist es viel versprechend die Methoden der Psychotherapieforschung zur Untersuchung von Ergebnis und Prozess von Coachingma?nahmen anzuwenden.      

试论《周易》的原初意义与现代意义

文章首先阐述了考察《周易》价值的方法,然后运用这一方法全面考察了《周易》的原初意义与现代意义。作者认为,《周易》的产生标志着中华民族抽象思维能力的关键性跃迁;《周易》的内容折射着当时的自然、社会和人文状况,记载着古代先民对于当时复杂的自然、社会和人生问题的特别关注与初步思考;《周易》的人生智慧和行为原则,反映着趋利避害和预见未来的价值取向;《周易》的思维方式汇集着当时的思维工具和认识方法,表达着最初的终极关怀和哲学意识。而《周易》所提供的始源性材料,有助于我们从根源性上来把握中华文化及其当代特点;易学史的演变与发展则为我们更好地把握历史文化发展进程提供了重要的思想资料;《周易》所表达的人生智慧和思维方式对于当今人类把握现实与面向未来也具有极为重要的启示和借鉴意义。