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This paper forms an introduction to this issue, the contents of which arose directly or indirectly from a conference in May 2001 on Corruption of scientific integrity? — The commercialisation of academic science. The introduction, in recent decades, of business culture and values into universities and research institutions is incompatible with the openness which scientific and all academic pursuit traditionally require. It has given rise to a web of problems over intellectual property and conflict of interest which has even led to corporate sponsors’ suppressing unfavourable results of clinical trials, to the detriment of patients’ health. Although there are those who see the norms of science developing to recognise the importance of instrumental science aiming at specific goals and of knowledge judged by its value in a context of application, none justifies the covert manipulation of results by vested interest.Public awareness of these problems is growing and creating a climate of opinion where they may be addressed. We suggest a way forward by the introduction of nationally and internationally-accepted guidelines for industrial collaboration which contain proper protections of the core purposes of universities and of the independence of their research. Some codes suggested for this purpose are discussed. We note that some universities are moving to adopt such codes of conduct, but argue the need for strong support from the government through its funding bodies. 相似文献
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Japanese exhibits two different types of morphological processes. Some morphologically complex predicates are generated within the domain of the lexicon, whereas others are generated outside the domain of the lexicon. An elicited production task involving both types of complex predicates was administered to six Japanese children with specific language impairment (JSLI) and six children with normal language development (JNLD). The JSLI children experienced significant difficulty forming the lexicon-external complex predicates but much less difficulty with the lexicon-internal complex predicates while the performance of the JNLD children exhibited no such asymmetry. These preliminary results suggest that the deficit of SLI affects the ability to construct implicit procedural rules for morphology that are generated outside the lexicon while their lexical operations for morphology that are generated within the domain of the lexicon remain relatively unimpaired. 相似文献
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Tsimpli IM 《Brain and language》2001,77(3):432-448
This paper includes (i) a comparison of the developmental pattern of certain morphosyntactic features in normally developing (ND) Greek children with similar data from a group of children with specific language impairment and (ii) a new analysis of the differences found. The analysis is based on a minimalist notion of LF interpretability. Depending on the feature-specification of lexical items (i.e., [+/- interpretable] at LF), a different route of development follows. In addition, phonological salience of both interpretable and noninterpretable features is argued to play an important role in an account of crosslinguistic differences in both normal and exceptional development. 相似文献
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Sjoerd L. Bonting 《Zygon》1999,34(2):323-332
Comparison of the concepts of creation from chaos and creation out of nothing ( creatio ex nihilo ) leads me to reject the latter for several reasons: it is not the biblical concept, and it presents serious conceptual, scientific, and theological problems. Chaos theology is outlined under the headings creation from chaos; chaos and contingency; chaos, evil, and creativity; chaos and incarnation; chaos and eschatology. It is shown to be well suited for the science-theology dialogue by some examples of its application to aspects of cosmic and biological evolution: initial mystery, separation and ordering; chaos and entropy; contingency and fine-tuning of the universe; purpose and progressiveness in evolution; and complexity theory and chaos events. 相似文献
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兴奋性氨基酸(EAAs) 广泛分布于中枢神经系统,参与多种生理过程包括学习、记忆和伤害感受等。然而,EAAs 受体的过度兴奋却可引发一系列细胞事件,最终导致神经元的损伤与死亡。许多神经退行性疾病如早老性痴呆、癫痫和肌侧索硬化症等都与EAAs 的兴奋毒作用有关。目前的研究表明,由EAAs 受体过度兴奋所引发的细胞内钙超载是导致神经元死亡的最终途径 相似文献
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Jake Epker Ann Matt Maddrey Randall Rosenblatt 《Journal of clinical psychology in medical settings》1999,6(4):393-403
The Multidimensional Pain Inventory (MPI) was utilized in a sample of adult outpatients with cystic fibrosis (CF) to assess their perception of pain and its psychosocial consequences. Subsequently, the data were compared to the ratings of pain and pain-related impairment in these patients as perceived by two nurses from the CF treatment team, as well as to a quantitative measure of illness severity. The results of these comparisons demonstrate that the majority of adult outpatients with CF reported experiencing lower levels of pain and pain-related impairment than expected, although the male patients tend to report experiencing significantly less impact in these domains than do the female patients. Additionally, the nurses do not underestimate the degree to which patients, especially males, experience pain and pain-related interference from chronic illness. Finally, there was no significant relationship between patients' self-report of pain severity or pain-related interference and an objective measure of disease severity. 相似文献
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