类别学习和分类运用的神经机制

从类别学习和分类运用(包括非人类对象分类和社会分类)两个方面阐述了分类的神经机制。类别学习主要与新皮层、内侧颞叶、基底神经节、中脑多巴胺能系统有关, 不同类别的学习会激活这些神经系统间不同的连接。对非人类对象分类时, 不同类型、级别、熟悉度及相似度类别分类的神经机制不同, 分类对象的清晰度、类别不确定性会影响分类的神经机制, 在分类进程的不同时段会出现对应的ERP指标。社会分类时个体先注意到外群体再加工内群体, 且对内群体的加工更深, P200和N200是对内、外群体区分的特异性波, 内外群体分类时, 内群体激活梭状回和扣带回后部, 外群体激活杏仁核。文章最后比较了人类和灵长类动物分类神经机制的异同, 并指出社会分类和非人类对象分类神经机制的整合以及人类和灵长类动物分类神经机制的比较是今后研究需要关注的问题。     

环境伦理学中的道德客体与正义取向

本文尝试通过分析现今较为流行的几种环境伦理观倡导的环境义务对象及其理论根据,指出其合理因素和缺陷所在,进而提出价值共同体的概念,以此阐明人类在环境义务对象上的多样性和复杂性,并提出一种兼顾多层次对象的环境正义观。     

Unconscious phantasy: Some historical and conceptual dimensions

This paper seeks firstly to grasp both conceptually and historically the different phenomenologies that are captured by the term ‘Unconscious Phantasy’. The term is shown to refer to a number of distinct though overlapping conceptual domains. These include: phantasy as scene, phantasy as representation of drive, phantasy as representation of wish as its fulfilment, phantasy as split off activity of the mind functioning under the aegis of the pleasure principle; phantasy as representation of the minds own activities (which Wollheim calls’ the way “the mind represents its own activities to itself’’). Lastly unconscious phantasy is understood as being the basic foundation of all mental life, including drives, impulses, all anxiety situations and defences. Having mapped out this territory through following the development of the concept in the work of Freud and Klein, the author draws on the work of the philosopher Richard Wollheim who, the author contends, has made a fundamental contribution to our conceptual understanding of unconscious phantasy. In the last section of the paper, the author draws a distinction between what he terms ‘objects’ (namely psychic objects) and what he terms ‘facts’. It is suggested that this distinction, though implicit in much of our work, benefits from being made explicit and that in so doing an important dimension of analytic work is illuminated. We aim to help the patient to discover what he is like, to understand the ways in which he conceives and misconceives himself, to unravel the fact‐ness of himself and his world from its ‘object qualities’, to differentiate between unconscious phantasy and reality.     

A place within the heart: finding a home with parental objects

For adopted and Looked After children with compromised early experiences, there can be troubling phantasies and anxieties associated with parental objects. These internal object relations can seriously restrict the development of secure intimate relationships with new parental figures. Adoptive parents and foster carers bear the brunt of the associated difficulties. Clinical work with the child, parents/carers, family, or network, may help processes of containment, differentiation, working through, mourning, and integration. This paper is based on thinking derived from clinical work with children who are adopted or Looked After, and with adoptive parental couples, carers, and networks. The primary focus is on how the child needs to find a ‘psychic home’ in the minds of others for their damaged internal parental objects, and the emotional capacities required in adoptive parents to provide this. I describe some of the complexities for adoptive parents and others in providing what is needed to enable the child to experience their internal parental objects in a fuller way. This process can allow the child to introject, identify with, and re-imagine their internal parental objects, and through this develop a more realistic relationship to their adoptive parents and to their birth parents. It promotes trust, freedom, and emotional depth in the relationship with parental figures.     

Bimanual tapping of a syncopated rhythm reveals hemispheric preferences for relative movement frequencies

In bimanual multifrequency tapping, right-handers commonly use the right hand to tap the relatively higher rate and the left hand to tap the relatively lower rate. This could be due to hemispheric specializations for the processing of relative frequencies. An extension of the double-filtering-by-frequency theory to motor control proposes a left hemispheric specialization for the control of relatively high and a right hemispheric specialization for the control of relatively low tapping rates. We investigated timing variability and rhythmic accentuation in right handers tapping mono- and multifrequent bimanual rhythms to test the predictions of the double-filtering-by-frequency theory. Yet, hemispheric specializations for the processing of relative tapping rates could be masked by a left hemispheric dominance for the control of known sequences. Tapping was thus either performed in an overlearned quadruple meter (tap of the slow rhythm on the first auditory beat) or in a syncopated quadruple meter (tap of the slow rhythm on the fourth auditory beat). Independent of syncopation, the right hand outperformed the left hand in timing accuracy for fast tapping. A left hand timing benefit for slow tapping rates as predicted by the double-filtering-by-frequency theory was only found in the syncopated tapping group. This suggests a right hemisphere preference for the control of slow tapping rates when rhythms are not overlearned. Error rates indicate that overlearned rhythms represent hierarchically structured meters that are controlled by a single timer that could potentially reside in the left hemisphere.     

Temporal predictive mechanisms modulate motor reaction time during initiation and inhibition of speech and hand movement

Skilled movement is mediated by motor commands executed with extremely fine temporal precision. The question of how the brain incorporates temporal information to perform motor actions has remained unanswered. This study investigated the effect of stimulus temporal predictability on response timing of speech and hand movement. Subjects performed a randomized vowel vocalization or button press task in two counterbalanced blocks in response to temporally-predictable and unpredictable visual cues. Results indicated that speech and hand reaction time was decreased for predictable compared with unpredictable stimuli. This finding suggests that a temporal predictive code is established to capture temporal dynamics of sensory cues in order to produce faster movements in responses to predictable stimuli. In addition, results revealed a main effect of modality, indicating faster hand movement compared with speech. We suggest that this effect is accounted for by the inherent complexity of speech production compared with hand movement. Lastly, we found that movement inhibition was faster than initiation for both hand and speech, suggesting that movement initiation requires a longer processing time to coordinate activities across multiple regions in the brain. These findings provide new insights into the mechanisms of temporal information processing during initiation and inhibition of speech and hand movement.     

Dummett and Frege on sense and Selbständigkeit

As part of his attack on Frege’s ‘myth’ that senses reside in the third realm, Dummett alleges that Frege’s view that all objects are selbständig (‘self-subsistent’, ‘independent’) is an underlying mistake, since some objects depend upon others. Whatever the merits of Dummett’s other arguments against Frege’s conception of sense, this objection fails. First, Frege’s view that senses are third-realm entities is not traceable to his view that all objects are selbständig. Second, while Frege recognizes that there are objects that are dependent upon other objects, he does not take this to compromise the Selbständigkeit of any objects. Thus, Frege’s doctrine that objects are selbständig does not make the claim of absolute independence that Dummett appears to have taken it to make. Nevertheless, in order to make a good case against Frege based on the dependency of senses, Dummett need only establish his claim that senses depend upon expressions: appeal to an absolute conception of independence is unnecessary. However, Dummett’s arguments for the dependency of senses upon expressions are unsuccessful and they show that Dummett’s conception of what it is to be an expression also differs significantly from Frege’s.     

Preflexes and internal models in biomimetic robot systems

The next generation of neuroprostheses, which are aimed at the restoration of natural movement of paralysed body parts or at the natural interaction with external devices, will be quite similar to biomimetic robot systems which attempt to duplicate the organization of the biological motor control system. In the paper, we review some of the organizing principles that have emerged in the last few years and might provide useful guidelines for a biomimetic design.     

论《黄帝内经》的医学哲学思想

被历代医学家奉为"医家之宗"的<黄帝内经>,同时也是当之无愧的"医学哲学之宗":其对医学普遍问题的研究、对医学整体思维观念的创立、对临床思维一般方法的阐述和对医学人文品格的揭示,都是中国医学思想史和医学哲学思想史上的开山之作.     

Predicting complex syntactic structure in real time: Processing of negative sentences in Russian

In Russian negative sentences the verb’s direct object may appear either in the accusative case, which is licensed by the verb (as is common cross-linguistically), or in the genitive case, which is licensed by the negation (Russian-specific “genitive-of-negation” phenomenon). Such sentences were used to investigate whether case marking is employed for anticipating syntactic structure, and whether lexical heads other than the verb can be predicted on the basis of a case-marked noun phrase. Experiment 1, a completion task, confirmed that genitive-of-negation is part of Russian speakers’ active grammatical repertoire. In Experiments 2 and 3, the genitive/accusative case manipulation on the preverbal object led to shorter reading times at the negation and verb in the genitive versus accusative condition. Furthermore, Experiment 3 manipulated linear order of the direct object and the negated verb in order to distinguish whether the abovementioned facilitatory effect was predictive or integrative in nature, and concluded that the parser actively predicts a verb and (otherwise optional) negation on the basis of a preceding genitive-marked object. Similarly to a head-final language, case-marking information on preverbal noun phrases (NPs) is used by the parser to enable incremental structure building in a free-word-order language such as Russian.