Neuropsychological Performance in Gulf War Era Veterans: Traumatic Stress Symptomatology and Exposure to Chemical–Biological Warfare Agents

Because complaints of diminished concentration and memory are among the most common health symptoms reported by Gulf War (GW) veterans with unexplained illnesses, this study investigated neuropsychological functions among GW veterans and controls. Relationships between neuropsychological performance, severity of posttraumatic stress disorder (PTSD) symptomatology, and exposure to chemical–biological warfare agents (CBW) were assessed. Participants were 225 veterans recruited from three cohorts: GW-deployed veterans from Ft. Devens, MA ( n = 141) and New Orleans, LA (n = 37), and Germany-deployed veterans from a Maine National Guard unit (n = 47). A comprehensive evaluation was completed. Severity of subclinical PTSD symptomatology was significantly related to scores on specific neuropsychological tests. PTSD symptom severity in GW-deployed veterans was found to be greater and associated with a broader range of neuropsychological deficits than in Germany-deployed veterans. PTSD severity was associated with lower performance on a range of neuropsychological tasks, whereas CBW exposure contributed to performance deficits on specific cognitive tasks.     

Representing decision-makers using styles of behavior: An approach designed for group decision support systems

Supporting decision-making processes when the elements of a group are geographically dispersed and on a tight schedule is a complex task. Aiming to support decision-makers anytime and anywhere, Web-based group decision support systems have been studied. However, the limitations in the decision-makers’ interactions associated to this scenario bring new challenges. In this work, we propose a set of behavioral styles from which decision-makers’ intentions can be modelled into agents. The goal is that, besides having agents represent typical preferences of the decision-makers (towards alternatives and criteria), they can also represent their intentions. To do so, we conducted a survey with 64 participants in order to find homogeneous operating values so as to numerically define the proposed behavioral styles in four dimensions. In addition, we also propose a communication model that simulates the dialogues made by decision-makers in face-to-face meetings. We developed a prototype to simulate decision scenarios and found that agents are capable of acting according to the decision-makers’ intentions and fundamentally benefit from different possible behavioral styles, just as a face-to-face meeting benefits from the heterogeneity of its participants.     

Salvaging the Biological Design Argument in Light of Darwinism?

It is a common assumption that biological organisms appear as though they were designed. Prior to the Darwinian revolution, the order of biological organisms was often taken as a sign of their divine Creator. It is also commonly argued that Darwinian evolutionary theory as a good explanation for the adaptive complexity of biology reveals this appearance to be merely an illusion. However, in recent philosophical discussion several defenses of the compatibility of divine design and Darwinian evolution have emerged. These defenses insist not only that divine design and evolution are compatible, but even that biological organisms can continue to function as pointers to the Creator, even in a Darwinian cosmos. This article explores and extends these recent arguments. I analyze four different strategies for arguing that the wisdom of the Creator is apparent in biological organisms. The basic underlying assumption is that the products of some larger whole can reflect the rationality and designedness of that whole.     

Experience-grounded semantics: a theory for intelligent systems

An experience-grounded semantics is introduced for an intelligent reasoning system, which is adaptive, and works with insufficient knowledge and resources. According to this semantics, truth and meaning are defined with respect to the experience of the system – the truth value of a statement indicates the amount of available evidence, and the meaning of a term indicates its experienced relations with other terms. The major difference between experience-grounded semantics and model-theoretic semantics is that the former does not assume the sufficiency of knowledge and resources. This approach provides new ideas to the solution of some important problems in cognitive science.     

Four Principles of Evolutionary Pragmatics in Jacob's Philosophy of Modern Biology

The French molecular biologist François Jacob outlined a theory of evolution as tinkering. From a methodological point of view, his approach can be seen as a biologic specification of the relation between laws, describing coherently the dynamics of a system, and contingent boundary conditions on this dynamics. From a semiotic perspective, tinkering is a pragmatic concept well-known from the information-theoretic anthropology of Claude Lévi-Strauss. In idealized contrast to an engineer, the tinkerer has to accept the concrete restrictions on his material resources as only gradually changeable constraints on his projects. Jacobian biopragmatics examines evolution as a biologic analogue to human tinkering devoid of any projecting subjectivity. To validate this analogy, four basic principles concerning main formal aspects of evolutionary objects, agents, histories, and consistency criteria are proposed.This revised version was published online in October 2005 with corrections to the Cover Date.     

Levels of modality for BDI Logic

The use of rational agents for modelling real world problems has both been heavily investigated and become well accepted, with BDI (Beliefs, Desires, and Intentions) Logic being a widely used architecture to represent and reason about rational agency. However, in the real world, we often have to deal with different levels of confidence in the beliefs we hold, desires we have, and intentions that we commit to. This paper extends our previous framework that integrated qualitative levels of beliefs, desires, and intentions into BDI Logic. We describe an expanded set of axioms and properties of the extended logic. We present a modular structure for the semantics which involves a non-normal Kripke type semantics that may be used for other agent systems. Further, we demonstrate the usefulness of our framework with a scheduling task example.     

什么决定着用户对产品的完整体验?

用户体验是以用户与产品的交互为基础而形成的用户对产品的完整感受。研究其决定因素可以有针对性地提高用户体验。早期研究表明, 可用性、美感和情感都有重要影响但皆不是唯一的决定因素, 近年来的研究重点关注于多因素整合理论及其模型的建立。在总结实效/享乐结构理论、用户-企业-产品双层结构理论和四种过程模型以提取用户体验影响因素的基础上, 提出目前研究的突破点可在三方面, 一是深入探讨各因素的作用, 二是揭示社会型产品用户体验的形成规律, 三是揭示用户体验随时间变化的规律。     

抗菌药物合理应用的宏观和微观问题

抗菌药物不合理应用现象长期得不到纠正,细菌耐药稳步攀升,正引起医学界、社会和政府的高度关注。本文就宏观上的抗菌药物使用政策与微观上的临床用药两方面存在的问题进行探讨。介绍了国际上关于抗菌药物政策的研究以及抗菌药物合理使用的新观点（尽早开始经验性治疗、“降阶梯”治疗策略、运用抗菌药物PK／PD原理指导临床用药、短程治疗）。主张调整宏观抗生素策略,去除该政策单纯、片面限制使用和应用药敏实验结果指导临床用药绝对化的做法。吸纳国际上的新成果,强化监管力度,更多采用教育和技术手段。     

Empathy framework for embodied conversational agents

Empathy is a complex socio-emotional behavior that results from the interaction between affective and cognitive mechanisms. Equipping embodied conversational agents (ECAs) with empathic capacity can benefit from the integration and evaluation of these low and high level capabilities in a hierarchical manner. Following the theoretical background on empathic behavior in humans, this paper presents a framework to equip ECAs with real time multi-modal empathic interaction capabilities. We present the implementation of this framework, which includes basic dialogue capabilities as well as three levels of empathic behavior in a conversational scenario. Our approach is an inclusive stand on modeling levels of empathy and provides a baseline behavior for empathic interaction.