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951.
Rosalind D. Butterfield Greg J. Siegle Kyung Hwa Lee Cecile D. Ladouceur Erika E. Forbes Ronald E. Dahl Neal D. Ryan Lisa Sheeber Jennifer S. Silk 《Developmental science》2019,22(6)
The ways parents socialize their adolescents to cope with anxiety (i.e., coping socialization) may be instrumental in the development of threat processing and coping responses. Coping socialization may be important for anxious adolescents, as they show altered neural threat processing and over reliance on disengaged coping (e.g., avoidance and distraction), which can maintain anxiety. We investigated whether coping socialization was associated with anxious and healthy adolescents’ neural response to threat, and whether neural activation was associated with disengaged coping. Healthy and clinically anxious early adolescents (N = 120; M = 11.46 years; 71 girls) and a parent engaged in interactions designed to elicit adolescents’ anxiety and parents’ response to adolescents’ anxiety. Parents’ use of reframing and problem solving statements was coded to measure coping socialization. In a subsequent visit, we assessed adolescents’ neural response to threat words during a neuroimaging task. Adolescents’ disengaged coping was measured using ecological momentary assessment. Greater coping socialization was associated with lower anterior insula and perigenual cingulate activation in healthy adolescents and higher activation in anxious adolescents. Coping socialization was indirectly associated with less disengaged coping for anxious adolescents through neural activation. Findings suggest that associations between coping socialization and early adolescents’ neural response to threat differ depending on clinical status and have implications for anxious adolescents’ coping. 相似文献
952.
Jessica Gilsoul Jessica Simon Michaël Hogge 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2019,26(2):282-317
The executive processes are well known to decline with age, and similar data also exists for attentional capacities and processing speed. Therefore, we investigated whether these two last nonexecutive variables would mediate the effect of age on executive functions (inhibition, shifting, updating, and dual-task coordination). We administered a large battery of executive, attentional and processing speed tasks to 104 young and 71 older people, and we performed mediation analyses with variables showing a significant age effect. All executive and processing speed measures showed age-related effects while only the visual scanning task performance (selective attention) was explained by age when controlled for gender and educational level. Regarding mediation analyses, visual scanning partially mediated the age effect on updating while processing speed partially mediated the age effect on shifting, updating and dual-task coordination. In a more exploratory way, inhibition was also found to partially mediate the effect of age on the three other executive functions. Attention did not greatly influence executive functioning in aging while, in agreement with the literature, processing speed seems to be a major mediator of the age effect on these processes. Interestingly, the global pattern of results seems also to indicate an influence of inhibition but further studies are needed to confirm the role of that variable as a mediator and its relative importance by comparison with processing speed. 相似文献
953.
Aimee James Karstens Inez Korzun Erich T. Avery Michelle T. Kassel Rachel Keelan Helen Kales 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2019,26(4):507-520
Altered HPA-axis functioning is a hypothesized mechanism for worsened cognition in depression. The current study examines the indirect effects of depression on processing speed, executive functioning, and memory as a function of the HPA-axis. 38 individuals with a depression diagnosis and 50 healthy controls (HCs) aged 18–86 underwent neuropsychological testing and at-home diurnal salivary cortisol collection. Depression was assessed via structured clinical interviews and rating scales. Cognitive composite scores were derived from factor analysis. Daytime cortisol exposure was estimated using area under the curve (AUC). Depression was associated with higher cortisol levels and slower processing speed . A significant suppression effect of AUC was present on the relationship between depression and processing speed. Limitations include the cross-sectional design and limited sample heterogeneity. Though poorly modulated HPA-axis is one proposed mechanism of cognitive alterations in depression, our results did not support this conclusion for processing speed. Alternative mechanisms should be considered to inform interventions to target cognitive alterations in depression. 相似文献
954.
Computer Aided Decision (CAD) systems, based on 3D tomosynthesis imaging, could support radiologists in classifying different kinds of breast lesions and then improve the diagnosis of breast cancer (BC) with a lower X-ray dose than in Computer Tomography (CT) systems.In previous work, several Convolutional Neural Network (CNN) architectures were evaluated to discriminate four different classes of lesions considering high-resolution images automatically segmented: (a) irregular opacity lesions, (b) regular opacity lesions, (c) stellar opacity lesions and (d) no-lesions. In this paper, instead, we use the same previously extracted relevant Regions of Interest (ROIs) containing the lesions, but we propose and evaluate two different approaches to better discriminate among the four classes.In this work, we evaluate and compare the performance of two different frameworks both considering supervised classifiers topologies. The first framework is feature-based, and consider morphological and textural hand-crafted features, extracted from each ROI, as input to optimised Artificial Neural Network (ANN) classifiers. The second framework, instead, considers non-neural classifiers based on automatically computed features evaluating the classification performance extracting several sets of features using different Convolutional Neural Network models.Final results show that the second framework, based on features computed automatically by CNN architectures performs better than the first approach, in terms of accuracy, specificity, and sensitivity. 相似文献
955.
Nowadays, the internet plays a major role in online information retrieval. As, we are well aware the web provides information related all the fields like national, lifestyle, movies, shopping, spirituality, sports, entertainment and much more. One cannot assume that the web retrieved information is believable or trustworthy due to multiple answers to the same query. The paper aims to study many research articles which are related to truth information discovery. However, the paper found that there is no proper research to find trustworthiness of news content which is extracted from multiple information sources with minimum misclassification error and retrieval time. To alleviate these issues, the truth content discovery algorithm is proposed to produce trustworthy information with minimal time along with multiple domain news information. The system provides reliable information from a various source of news provider with minimum classification error. The proposed method ranked the news content index based on query matches from extracted information. It minimizes the query retrieval time and classification error. Based on the experimental evaluation, proposed TCD + J48 algorithm produced the best result compared to existing approaches. It minimizes reduces 7.54 ms the query retrieval time (QRT), 5% Error rate (ER) and 0.98 and Mean Normalized Absolute Distance (MNAD). 相似文献
956.
药物成瘾者存在决策缺陷, 并表现出冲动性、风险寻求、奖赏失调、躯体内感信号缺失等特征。神经影像学研究表明药物滥用导致成瘾者背外侧前额皮层、前扣带回、眶额叶皮层、腹内侧前额皮层、杏仁核、脑岛等脑区受损, 这些损伤是引发其决策缺陷的主要原因。认知训练有利于提高个体的决策能力, 如目标管理训练和正念冥想等可以增强个体工作记忆、促进自我觉察和以目标为导向的行为; 而非侵入性脑刺激则可以直接改变与成瘾者决策相关脑区的激活状态, 从而提升与决策相关的认知功能。总体而言, 未来认知训练和非侵入性脑刺激在成瘾干预方面仍有广阔的拓展空间。 相似文献
957.
958.
近年来, 随着音乐的神经科学与神经美学的发展, 逐渐形成一个新的研究领域, 即音乐的神经美学。这一研究领域关注音乐审美的心理过程和神经机制, 将注意力集中于音乐审美活动中的感知、认知和情感解释。音乐审美加工引起了相应的审美反应, 其中有三种音乐审美反应得到研究者更多的关注, 即音乐审美情绪、判断与偏好。研究者围绕这三种反应, 对音乐审美反应的知觉、认知、情绪加工和影响因素以及其神经机制展开研究。这些研究为我们理解音乐和美学的行为与神经机制提供了经验性证据。 相似文献
959.
960.
We studied the pattern of performance in elementary school children and adults detecting a target in compound geometric shapes. The target was randomly presented at the global, local, or neither level of compound shapes with different elemental density. A significant difference between the pattern of performance in children and adults emerged when the geometric shape was constructed with fewer constituent parts. That is, children showed difficulties in recognizing the global level while adults could efficiently process it. We suggest that global processing continues to develop as children grow older. Also, integration ability could benefit from increasing familiarity with the geometric concepts. 相似文献