Impaired awareness of movement disorders in Parkinson’s disease

Background

This study analyzed the presence of awareness of movement disorders (dyskinesias and hypokinesias) in 25 patients with Parkinson’s disease (PD) and motor fluctuations (dyskinesias, wearing off, on–off fluctuations). Of the few studies that have dealt with this topic, none have analyzed the differences in the awareness of motor deficits by comparing the on and off states using motor scales and an extensive battery of tests to assess cognitive and behavioral functioning.

Methods

PD patients were compared on three different scales that we have devised to measure awareness of movement disorders: Global Awareness of Movement (GAM) Disorders, dyskinesia/hypo-bradykinesia rating scales.

Results

Data showed that PD patients had greater awareness and psychological suffering in the off state than in the on state. In particular, they were troubled by motor disabilities related to hypokinesias and had mood-related symptoms and a perception of disability in activities of daily living. Interestingly, patients only showed a selective reduction of awareness of movement disorders associated with executive functions and related to dyskinesias in the on state, compared to a preserved awareness of hypokinesias in the off state. On the contrary, no association with executive functions was found in the off state.

Conclusion

Our findings suggest that the dopaminergic overstimulation of mesocorticolimbic pathways may cause a dysfunction of prefrontal–subcortical connections related to the impaired insight.     

Fitts’ law holds for pointing movements under conditions of restricted visual feedback

Fitts’ law robustly predicts the time required to move rapidly to a target. However, it is unclear whether Fitts’ law holds for visually guided actions under visually restricted conditions. We tested whether Fitts’ law applies under various conditions of visual restriction and compared pointing movements in each condition. Ten healthy participants performed four pointing movement tasks under different visual feedback conditions, including full-vision (FV), no-hand-movement (NM), no-target-location (NT), and no-vision (NV) feedback conditions. The movement times (MTs) for each task exhibited highly linear relationships with the index of difficulty (r² > .96). These findings suggest that pointing movements follow Fitts’ law even when visual feedback is restricted or absent. However, the MTs and accuracy of pointing movements decreased for difficult tasks involving visual restriction.     

运动轨迹和方向对视觉空间关系加工的影响

视觉空间关系分为类别与数量两种表征。研究通过控制起参照作用的运动客体消失状态与定位客体出现时间,分析客体运动信息对两种关系判断的影响。结果发现:运动信息在各间隔时间对类别任务影响呈序列排列,运动方向较轨迹信息有优势,轨迹较法线信息有优势;数量表征仅在0ms间隔受运动方向促进,在其他间隔下,三种位置上的判断均无差异。结果表明运动客体类别表征比数量表征更持久;且相对类别表征,数量判断作为精确距离表征不易受运动方向和轨迹信息影响。     

词汇获得年龄效应的眼动研究

采用两个实验考察了获得年龄因素在汉语词汇识别中的作用。实验一采用经典的词汇判断任务考察了获得年龄和词频因素在词汇判断中的作用,结果发现获得年龄和词频两个因素均影响词汇识别。实验二采用阅读句子任务,通过实时记录的眼动追踪技术进一步考察了在有语境的情况下,获得年龄和词频因素在词汇加工中的作用。结果发现,在阅读句子任务中,词汇获得年龄和词频因素都在词汇加工中起作用,二者存在交互作用,晚获得词存在词频效应。两个实验的结果均支持了在汉语词汇识别中,存在获得年龄效应。     

自由拦截启动策略与信息利用

手的启动方向自由, 伸手拦截不同速度的运动小球。本研究通过考察手启动时的运动参数, 研究自由启动的情况下的信息利用和拦截策略, 并且考察了人的启动模式。结果发现, 自由拦截时手的拦截区域相对固定, 在物体快速运动情景下启动晚, 而在慢速下启动早, 可能综合利用了接触时间和距离信息, 存在速度伴随效应, 手的拦截启动策略为启动有相对稳定的角度和加速度, 并不随物体运动速度和物体大小的改变而改变。     

汉语句子理解中句法启动机制的眼动和ERP研究

语言产生的句法启动效应在近20年得到较深入研究。那么, 语言理解和语言产生中, 句法启动效应具有相同的加工机制吗？近些年, 研究者考察了印欧语系语言理解中的启动效应, 但还存在较多争论。这究竟是句法效应, 还是策略或者语义效应, 是词汇驱动还是词汇独立的？而且, 这是人类语言理解的语系特性还是普遍特性？单独采用行为技术、眼动技术或者ERP技术很难为这些争论提供坚实的实验证据和较深入的理论解释。鉴于此, 本项目拟采用眼动和ERP结合的技术, 从心理学、语言学和认知神经科学等多学科交叉的视角考查汉语句子理解的句法启动效应。通过分析眼动和ERP实验提供的一致性和差异性证据, 本项目力图阐明和揭示汉语句子理解中句法启动效应的认知特点和机制, 检验内隐学习理论和论元结构理论在解释句法启动效应时的适用性。     

What Motivates People to Participate More in Community‐based Coalitions?

The purpose of this study was to identify potential opportunities for improving member participation in community-based coalitions. We hypothesized that opportunities for influence and process competence would each foster higher levels of individual member participation. We tested these hypotheses in a sample of 818 members within 79 youth-oriented coalitions. Opportunities for influence were measured as members' perceptions of an inclusive board leadership style and members' reported committee roles. Coalition process competence was measured through member perceptions of strategic board directedness and meeting effectiveness. Members reported three types of participation within meetings as well as how much time they devoted to coalition business beyond meetings. Generalized linear models accommodated clustering of individuals within coalitions. Opportunities for influence were associated with individuals' participation both within and beyond meetings. Coalition process competence was not associated with participation. These results suggest that leadership inclusivity rather than process competence may best facilitate member participation.     

不同难度阅读材料对阅读知觉广度影响的眼动研究

采用经典的呈现随眼动变化技术,以Eyelink II眼动仪为工具,考察材料难度和窗口大小对中文句子阅读的影响.实验设计为2(材料难度:难,易)× 5(窗口大小:1个字,3个字,5个字,7个字和整行)被试内实验设计,被试为15名在校大学生.研究结果表明:(1)阅读容易材料时的知觉广度为5个字.(2)阅读困难材料时知觉广度为3-5个字.     

Who do students with mild disabilities nominate as cool in inclusive general education classrooms?

Examined the nominations that elementary students with mild disabilities made for peers they perceived as cool. The total sample was comprised of 948 students (496 girls, 452 boys) from the metropolitan Chicago area and North Carolina and included 107 (11.3%) students with mild disabilities. Overall, students with mild disabilities nominated prosocial and athletic peers who affiliate with students with mild disabilities. However, aggressive boys who are central in the social network were highly likely to view aggressive peers as cool. Results are discussed in relation to implications for social interventions for students with mild disabilities.     

The paradox of the disrespected: Disrespected group members’ engagement in group-serving efforts

Previous research has demonstrated that intra-group respect can strengthen people’s group identification, and encourage them to exert themselves on behalf of their group. In the present contribution, we focus on the possibility that those who are not respected by other group members (i.e., the disrespected) can also display group beneficial behavior. Experiment 1 (N = 159) confirms this paradoxical premise and reveals that systematically disrespected group members indeed exert themselves on group-serving tasks. These findings were replicated in Experiment 2 (N = 110). Additional indicators in Experiment 2 demonstrate that the effort by systematically disrespected group members cannot be attributed to a desire to improve their acceptance in the group, but should be interpreted as attempts to assert the worth of the self separately from the group. Results are discussed in relation to the group-value model and insights on marginal group membership and social exclusion.