Spatial limits on referred touch to an alien limb may reflect boundaries of visuo-tactile peripersonal space surrounding the hand

In this study, the spatial limits of referred touch to a rubber hand were investigated. Participants rated the strength of the perceived illusion when the rubber hand was placed in one of six different spatial positions (at a distance of 17.5-67.5cm horizontal from the participant's own hand). The results revealed a significant nonlinear relationship in the strength of the illusion, with the strongest ratings given when the two hands were closest; decaying significantly after a distance of 30cm. The time taken to elicit the illusion followed a similar trend. These results may reflect the response properties of bimodal visuo-tactile cells encoding peripersonal space around the hand.     

The influence of suspect ethnicity and evidence direction on alibi credibility assessment

We investigated whether evidence direction (incriminating versus exonerating) moderated the influence of intergroup bias on alibi credibility assessments. Israeli-Jewish participants (n = 160) assessed the credibility of an alibi statement provided by either an Israeli-Jewish or an Israeli-Arab suspect. Along with the alibi statement, half of the participants were presented with incriminating evidence, while the other half were presented with exonerating evidence. The results indicated that evidence direction influenced credibility assessment regarding both in-group and out-group suspects. Specifically, under incriminating evidence, Israeli-Jewish suspects were perceived as more deceptive than Israeli-Arab suspects, whereas under exonerating evidence, no such differences were found. These results emphasize the significance of group bias in assessing the credibility of alibi statements.     

胰岛细胞再生研究的临床应用前景

胰岛细胞再生是治愈1型糖尿病和胰岛β细胞功能丧失的2型糖尿病的根本途径。体外再生和体内再生两种策略都是通过将干细胞或其他类型体细胞分化或转化为胰岛细胞后发挥胰岛素分泌功能,从而治疗糖尿病。基础研究显示,两者存在着各自的优势和面临的问题。胰岛细胞再生治疗的临床应用前景尚需要进一步加以考证。     

Memory influences on hippocampal and striatal neural codes: effects of a shift between task rules

Interactions with neocortical memory systems may facilitate flexible information processing by hippocampus. We sought direct evidence for such memory influences by recording hippocampal neural responses to a change in cognitive strategy. Well-trained rats switched (within a single recording session) between the use of place and response strategies to solve a plus maze task. Maze and extramaze environments were constant throughout testing. Place fields demonstrated (in-field) firing rate and location-based reorganization [Leutgeb, S., Leutgeb, J. K., Barnes, C. A., Moser, E. I., McNaughton, B. L., & Moser, M. B. (2005). Independent codes for spatial and episodic memory in hippocampal neuronal ensembles. Science, 309, 619-623] after a task switch, suggesting that hippocampus encoded each phase of testing as a different context, or episode. The task switch also resulted in qualitative and quantitative changes to discharge that were correlated with an animal's velocity or acceleration of movement. Thus, the effects of a strategy switch extended beyond the spatial domain, and the movement correlates were not passive reflections of the current behavioral state. To determine whether hippocampal neural responses were unique, striatal place and movement-correlated neurons were simultaneously recorded with hippocampal neurons. Striatal place and movement cells exhibited a response profile that was similar, but not identical, to that observed for hippocampus after a strategy switch. Thus, retrieval of a different memory led both neural systems to represent a different context. However, hippocampus may play a special (though not exclusive) role in flexible spatial processing since correlated firing amongst cell pairs was highest when rats successfully switched between two spatial tasks. Correlated firing by striatal cell pairs increased following any strategy switch, supporting the view that striatum codes change in reinforcement contingencies.     

客体运动方向的视觉工作记忆存储方式

采用变化觉察范式,以独立运动的客体为对象,通过两个实验,探讨多个客体的运动方向在视觉工作记忆中的存储机制,即单个对象独立存储,抑或其存储受多个客体构型的影响。实验一和实验二相继考察了非目标客体运动方向变化,以及是否存在非目标客体对觉察目标客体运动方向的影响。结果发现,非目标客体运动方向变化条件下的觉察正确率显著低于不变的条件,然而只呈现目标客体条件下的觉察正确率与同时呈现目标和非目标条件无显著差异。该结果与前人在静态条件下对目标客体的觉察受目标客体和非目标客体整体构型影响的结论不一致。本研究的结果支持多个客体的运动方向信息在工作记忆中是以独立方式存储的假设。     

癫痫诊治中医患同盟建立的实践与策略

通过对肝硬化者行超声检测,预测食管静脉出血,结果显示,出血组门静脉及胃左静脉管径均增粗,但胃左静脉更明显,门静脉血流速减慢而胃左静脉增快;出血组胃左静脉均呈离肝血流,其分流指数明显增大。胃左静脉的管径及血流速与门静脉比较具有显著的变化,其分流指数和血流方向在预测出血方面具有更大的价值。     

非雄激素依赖型前列腺癌与肿瘤干细胞——浅析辩证思维之于临床医学的方法论作用

在前列腺癌的治疗中,由于癌细胞的不断“升级”使得治疗屡屡受挫。近来提出的肿瘤干细胞理论认为:肿瘤是一种干细胞疾病,只有消灭了“种子”,才能克服癌症。从自然辩证法的角度,结合肿瘤干细胞理论对前列腺癌的诊疗加以分析,解释非雄激素依赖型前列腺癌的发病机制,以一种新的思维指导临床治疗。     

自闭症幼儿自主性共同注意的实验研究

为探索和发现自闭症幼儿的自主性共同注意的特征,以6名自闭症幼儿,以及在心理年龄与之匹配的弱智和正常儿童各6名作为研究对象,以实验和准实验的方法,进行此研究。同时还以秒为单位对实验过程与结果进行编码分析。结果表明,自闭症幼儿的自主性视觉方向所及目标物多于人,而人的目标中叉更多地锁定同伴而非教师。自闭症幼儿在唤起他人共同注意时多以“拉”和“抱”来替代指点行为。自主性共同注意的发生率与情绪有密切关系。     

微创技术的发展:历史、现实和未来

根据"看"的技术不同,微创技术可以分为两类和三种.目前,微创技术正处于以内镜、腔镜、介入X-线、介入超声以及微创化外科技术为主的技术发展阶段.展望未来,微创技术可能出现三种发展趋势:(1)现有技术的进一步完善、提高;(2)现有不同技术的相互融合;(3)微创新技术的发明.