Habituation to repeated stress: get used to it

Habituation, as described in the landmark paper by Thompson et al. [Thompson, R. F., & Spencer, W. A. (1966). Habituation: A model phenomenon for the study of neuronal substrates of behavior. Psychological Review, 73(1), 16–43], is a form of simple, nonassociative learning in which the magnitude of the response to a specific stimulus decreases with repeated exposure to that stimulus. A variety of neuronal and behavioral responses have been shown to be subject to habituation based on the criteria presented in that paper. It has been known for several decades that the magnitude of hypothalamic–pituitary–adrenal (HPA) activation occurring in response to a stressor declines with repeated exposure to that same stressor. For some time this decline has been referred to as “habituation” in the stress neurobiology literature. However, how this usage compares to the definition proposed by Thompson and Spencer has not been systematically addressed. For this special issue, we review the stress neurobiology literature and examine the support available for considering declines in HPA response to repeated stress to be response habituation in the sense defined by Thompson and Spencer. We conclude that habituation of HPA activity meets many, but not all, important criteria for response habituation, supporting the use of this term within the context of repeated stress. However, we also propose that response habituation can, at best, only partially explain the phenomenon of HPA habituation, which also involves well-known negative feedback mechanisms, activation of broad stress-related neural circuitry and potentially more complex associative learning mechanisms.     

Dietary interventions,the gut microbiome,and aggressive behavior: Review of research evidence and potential next steps

Research in biosocial criminology and other related disciplines has established links between nutrition and aggressive behavior. In addition to observational studies, randomized trials of nutritional supplements like vitamins, omega-3 fatty acids, and folic acid provide evidence of the dietary impact on aggression. However, the exact mechanism of the diet-aggression link is not well understood. The current article proposes that the gut microbiome plays an important role in the process, with the microbiota–gut–brain axis serving as such a mediating mechanism between diet and behavior. Based on animal and human studies, this review synthesizes a wide array of research across several academic fields: from the effects of dietary interventions on aggression, to the results of microbiota transplantation on socioemotional and behavioral outcomes, to the connections between early adversity, stress, microbiome, and aggression. Possibilities for integrating the microbiotic perspective with the more traditional, sociologically oriented theories in criminology are discussed, using social disorganization and self-control theories as examples. To extend the existing lines of research further, the article considers harnessing the experimental potential of noninvasive and low-cost dietary interventions to help establish the causal impact of the gut microbiome on aggressive behavior, while adhering to the high ethical standards and modern research requirements. Implications of this research for criminal justice policy and practice are essential: not only can it help determine whether the improved gut microbiome functioning moderates aggressive and violent behavior but also provide ways to prevent and reduce such behavior, alone or in combination with other crime prevention programs.     

Soul,Myth and Cosmovision in a Changing World: Essentials of Analytical Psychology and the Descendent Path1

This essay addresses the key role of analytical psychology amid our changing world: to work towards an expansion of Humanity's worldview. In current times of utmost transformation, it becomes imperative that we embrace a total cosmovision, one that includes the 360 degrees of existence: not only the 180 diurnal degrees of ascent, light and order, yet also the descendent sphere, incorporating what is unconscious, nocturnal and mysterious. Integrating this lower realm in our psychic life, however, contrasts our Western worldview, in which these two domains are seemingly opposed and mutually excluding. Mythopoetic language, and the mythologems that manifest in different myths, provide the means of delving into the profound paradoxes at the core of the total cosmovision. Myths such as Añañuca (Chile), Osiris (Egypt), Dionysus (Greece) and Innana (Sumer), highlight the descending path, providing a symbolic narrative of an archetypical transformation or spin, a key moment of “turning on its own axis” that merges the realms of Life and Death, ascent and descent, birth and decay. To live this paradoxical and generative path of transformation, individuals must seek their personal myth not outside but within themselves, where springs the Suprasense.     

Attachment experience and cortisol recovery from romantic conflict among young Chinese couples: A dyadic analysis

Using a sample of young adults, the present study investigated how the participants' attachment to romantic partners was related to that with their parents and peers and how this specific attachment experience was associated with their physiological stress response. We examined 121 pairs of young Chinese (N = 242) heterosexual couples (men's age: 22.26 ± 2.40; women's age: 21.62 ± 2.22) and their attachment to parents, peers, and romantic partners as well as their cortisol recovery from romantic conflict. Robust actor–partner interdependence mediation models showed that women's insecure parental and peer attachment was associated with blunted cortisol recovery from romantic stress through their fearful attachment with romantic partners, whereas men's insecure parental and peer attachment was associated with their partners' adaptive cortisol recovery from romantic stress through their fearful romantic attachment. These findings suggested that women's hypothalamic–pituitary–adrenal-axis functioning seemed to be more strongly associated with their own and their partners' attachment relationships compared to men.     

Effects of the axis of rotation and primordially solicited limb of high level athletes in a mental rotation task

A recent set of studies has investigated the selective effects of particular physical activities that require full-body rotations, such as gymnastics and wrestling (Moreau, Clerc, Mansy-Dannay, & Guerrien, 2012; Steggemann, Engbert, & Weigelt, 2011), and demonstrated that practicing these activities imparts a clear advantage in in-plane body rotation performance. Other athletes, such as handball and soccer players, whose activities do require body rotations may have more experience with in-depth rotations. The present study examined the effect of two components that are differently solicited in sport practices on the mental rotation ability: the rotation axis (in-plane, in-depth) and the predominantly used limb (arms, legs). Handball players, soccer players, and gymnasts were asked to rotate handball and soccer strike images mentally, which were presented in different in-plane and in-depth orientations. The results revealed that handball and soccer players performed the in-depth rotations faster than in-plane rotations; however, the two rotation axes did not differ in gymnasts. In addition, soccer players performed the mental rotations of handball strike images slower. Our findings suggest that the development of mental rotation tasks that involve the major components of a physical activity allows and is necessary for specifying the links between this activity and the mental rotation performance.     

Physiological Correlates of Choice‐Induced Dissonance: An Exploration of HPA‐Axis Responses

Choice can produce a negatively arousing cognitive conflict (called dissonance), which is thought to motivate the chooser to spread their preferences for the relevant options (called Spreading of Alternatives, or SA). The current work aimed to determine the relationship between HPA‐axis activity and both choice‐induced dissonance and its reduction (i.e. SA) among individuals with varying cultural backgrounds. European–Americans and Asians made a choice between two equally attractive CDs either in the presence of a cue indicative of social eyes (i.e. public‐choice condition) or in the absence thereof (i.e. private‐choice condition). As predicted, European–Americans and Asians showed a reliable SA primarily in the private and public choice conditions, respectively. Importantly, a sharp decline of salivary cortisol was observed over the span of 30 min, and, moreover, this decline was reliably predicted by the magnitude of SA regardless of either culture or the choice being private vs. public. These results suggest that although choice‐induced dissonance is too weak to elicit an HPA‐axis stress response, SA is associated with variability in the decline of salivary cortisol during the laboratory task. Copyright © 2015 John Wiley & Sons, Ltd.     

神经及内分泌系统对社会支持缓冲应激的调节机制

应激是生活中不可避免的事件,过度应激也是许多疾病发生的诱因。应激会引起一系列生理反应,包括激活自主神经系统及神经内分泌系统,表现为自主神经系统(ANS)和下丘脑–垂体–肾上腺(HPA)活动的增加。社会支持通过改变或抑制应激相关脑区的活动,缓冲了应激引起的ANS和HPA轴活动,使机体快速恢复到应激前水平,避免应激引起的内稳定失衡对机体的伤害。     

“转换-坚持”对低阶层健康的保护作用及其机制

低社会阶层是不良健康状况最可靠的社会决定因素之一。然而, 很少有人理解为什么同样处于低阶层, 有些个体却能保持良好的健康状况。在大量实证研究的基础上, 研究者们发现“转换-坚持”策略这一心理因素能有效保护处于逆境中的低阶层者的健康, 使其免于受到疾病的侵扰。当个体面临持续或频繁的压力时, “转换-坚持”策略减轻了下丘脑-垂体-肾上腺轴的急性生理激活, 有效抑制了低阶层面临逆境时的生理应激反应, 随着时间的推移, 阻止了致病过程的发展; 同时, 该策略还减少了低阶层者的不良健康行为, 进而对健康起到保护作用。未来研究应在深入探索核心机制基础上开发出有效的干预方案, 为解决我国相对贫困问题中的健康贫困提供新的路径。     

Cognitive deficits in relation to personality type and hypothalamic-pituitary-adrenal (HPA) axis dysfunction in women with stress-related exhaustion

Exhaustion caused by long-term work-related stress may cause cognitive dysfunction. We explored factors that may link chronic stress and cognitive impairment. Personality, psychiatric screening, and behavior were assessed by self-reporting measures in 20 female patients (mean age 39.3 years; range 26-53) with a preliminary diagnosis of stress-related exhaustion and in 16 healthy matched controls. Cognitive performance was investigated with a detailed neuropsychological test battery. Cortisol axis function was assessed by urinary and saliva collections of cortisol, dexamethasone suppression, Synacthen response, and corticotropin-releasing hormone (CRH) tests. Proinflammatory cytokines were measured. Hippocampal volumes were estimated by magnetic resonance imaging. Multivariate and univariate statistical methods were used to explore putative differences between groups and factors linked to cognitive impairment. Cognitive function clearly differed between groups, with decreased attention and visuospatial memory in the patient group, suggesting frontal cortex/medial temporal cortex-network dysfunction. Increased harm avoidance and persistence was present among patients, with lowered self-directedness linked to lower quality of life, increased anxious and depressive tendencies, and experiences of psychosocial stress. Attention was decreased with concomitantly impaired visuospatial memory. The pituitary (adrenocorticotropic hormone, ACTH) response to CRH was decreased in patients, with an increased cortisol/ACTH response to CRH. However, cortisol production rates, diurnal or dexamethasone-suppressed saliva cortisol levels, and the cortisol response to Synacthen were unaltered. Hippocampal volumes did not differ between groups. These findings suggest that cognitive dysfunction in stress-related exhaustion is linked to distinct personality traits, low quality of life, and a decreased ACTH response to CRH.