Discerning the Limits of Religious Naturalism

In response to my "How to Make Naturalism Safe for Supernaturalism: An Evaluation of Willem Drees's Supernaturalistic Naturalism" (Rottschaefer 2001), Willem Drees maintains that I have misunderstood his purpose and views and have failed to make the case against his view that naturalism is intrinsically limited. In this response, I comment on these concerns.     

A computational model of frontal lobe dysfunction: working memory and the Tower of Hanoi task

A symbolic computer model, employing the perceptual strategy, is presented for solving Tower of Hanoi problems. The model is calibrated—in terms of the number of problems solved, time taken, and number of moves made—to the performance of 20 normal subjects. It is then "lesioned" by increasing the decay rate of elements in working memory to model the performance of 20 patients with lesions to the prefrontal cortex. The model captures both the main effects of subject groups (patients and normal controls) performance, and the subject groups (patients and normal controls) by problem difficulty interactions. This leads us to support the working memory hypothesis of frontal lobe functions, but for a narrow range of problems.     

Antiaggressive and motor effects of the DA release inhibitor CGS 10746B

In the present study the effects of a wide range of doses of the dopamine release inhibitor CGS 10746B were evaluated in spontaneous activity and in aggressive behaviour using the paradigm of isolation‐induced aggression. The two higher doses (8 and 16 mg/kg) produced a decrease in spontaneous motor activity. Antiaggressive effects were observed after administration of doses from 4 mg/kg upwards. At this dose, CGS 10746B diminished threat and attack, and although an increase in immobility was observed, no impairment of other motor behaviours was presented. With higher doses, aggression was practically abolished but with a concomitant effect on many other behaviours. When animals were separated depending on their latency of attack, those that showed a long attack latency (LAL) presented a stronger response to 4 mg/kg than those that had a short attack latency (SAL), which were not affected in their aggression by this dose. We can conclude that presynaptic dopamine function is necessary for the normal expression of aggressive behaviours, since CGS 10746B reduces aggression at doses that do not affect spontaneous motor activity. Aggr. Behav. 27:382–390, 2001. © 2001 Wiley‐Liss, Inc.     

The relation of the anger subcomponent of Type A behavior to psychological symptoms in Japanese and foreign students

The relations of the Type A behavior subcomponents to psychological symptoms were examined. Participants were 429 Japanese college students and 307 foreign students. Type A behavior was measured by the Everyday Behavior Questionnaire, developed in part from several rating scales and composed of four subcomponents: anger/impatience, speed, competitiveness/hard-driving, and eagerness/interest. The Hopkins Symptom Checklist was used to measure psychological symptoms. The results of multiple regression analyses on the Type A behavior subcomponents and psychological symptoms indicated strong positive relations between anger/impatience and psychological symptoms, in both Japanese and foreign students. It was concluded that the Type A subcomponents anger and impatience seemed to worsen the psychological health of individuals of various cultural backgrounds.     

In pursuit of a historical tradition: N. A. Rozhkov’s scientific laws of history

Despite all that has been written about Russian historiography and how it profoundly changed after the Bolsheviks seized power in 1917, very little is known about the historical tradition immediately before the Soviet era. This article attempts to begin to address this issue by examining the major forces that shaped the historical and sociological thought of Nikolai Alesandrovich Rozhkov (1868–1927). It argues that as Kliuchevskii’s successor and as the first professional historian to eventually present a Marxist analysis of Russian history, Rozhkov was not only the most important historian at that time but one whose work best represented the most significant transition in Russia’s historical tradition. The article concludes that an examination of Rozhkov’s historical methodology offers a new interpretation of the origins of Soviet historiography.

细胞周期相关因子cdt1和geminin的平衡

cdt1和geminin是重要的细胞周期相关因子,参与细胞周期的调控cdt1与某些疾病的发生有着密切的关系,geminin是cdt1的抑制因子,他们间的平衡对DNA复制;;基因稳定以及细胞周期的调控起着重要的作用,并已经在一些感染性疾病和肿瘤中证实     

要重视慢性乙型肝炎的抗病毒治疗

慢性乙型肝炎是我国常见的慢性传染病之一,严重危害人民健康。围绕着乙型肝炎的防治,带来巨大的经济负担,已成为不可忽视的社会问题。在慢性乙型肝炎-肝硬化-HCC的发生发展过程中,HBV病毒载量起着重要的作用,抗病毒治疗是目前治疗慢性乙型肝炎的有效手段。因此,要重视和规范抗病毒治疗。     

慢性乙型肝炎抗病毒治疗的进展

针对目前乙型肝炎的抗病毒治疗现状以及临床用药中存在的问题进行分析,就如何选择合理治疗方法提出医疗原则,认为对于慢性乙型肝炎的抗病毒治疗,应坚持联合治疗和个体化治疗,长期用药和间断反复用药结合,把病毒抑制到最低水平,以使发生原发性肝癌的可能性减至最小。     

SF-36量表用于慢性乙型肝炎生命质量测定的效果评价

评价SF-36量表在慢性乙型肝炎患者中应用的效果;调查101名慢性乙肝患者,用重测信度、分半信度、内部一致性、结构效度和判别效度等对SF-36量表进行评判;该量表具有良好的分半信度和内部一致性,结构效度和判别效度较好;SF-36量表可用于慢性乙型肝炎患者生命质量评价。