An Examination of Alcohol Use Disorder Symptoms and Neighborhood Disorganization from Age 21 to 39

Living in disorganized neighborhoods characterized by high levels of poverty, crime, violence, and deteriorating buildings has been associated with increased alcohol consumption and mental health problems. Data drawn from the Seattle Social Development Project (N = 790), a theory‐driven longitudinal study originating in Seattle, WA, were used to estimate trajectories of Alcohol Use Disorder (AUD) symptoms from age 21 to 39. Time‐varying measures of neighborhood disorganization, psychological distress, and sociodemographic factors were associated with deviations from average AUD symptoms at each wave. Results indicated that, on average, AUD symptoms decreased as individuals got older. Living in more disorganized neighborhoods and experiencing psychological distress was associated with increased AUD symptoms after accounting for average reductions from AUD symptoms over time and time‐varying measures of relevant sociodemographic factors. Results of mediation analysis suggested that psychological distress is a mechanism by which disorganized neighborhoods increased risk of AUD from age 21 to 39.     

Enhancing treatment effectiveness through social modelling: A pilot study

Objective: Medical treatments take place in social contexts; however, little research has investigated how social modelling might influence treatment outcomes. This experimental pilot study investigated social modelling of treatment effectiveness and placebo treatment outcomes.

Design: Fifty-nine participants took part in the study, ostensibly examining the use of beta-blockers (actually placebos) for examination anxiety. Participants were randomly assigned to observe a female confederate report positive treatment effects (reduced heart rate, relaxed, calm) or feeling no different.

Main outcome measures: Heart rate, anxiety and blood pressure were assessed, as were symptoms and attributed side effects.

Results: Heart rate decreased significantly more in the social modelling compared to control condition, p = .027 (d = .63), and there were trends towards effects in the same direction for both anxiety, p = .097 (d = .46), and systolic blood pressure, p = .077 (d = .51). Significant pre-post placebo differences in heart rate, anxiety and diastolic blood pressure were found in the social modelling group, ps < .007 (ds = .77–1.37), but not the control condition, ps > .28 (ds = .09–.59).

Conclusions: Social observation of medication effectiveness enhanced placebo effectiveness in heart rate, and showed a trend towards enhancing treatment effectiveness in both anxiety and systolic blood pressure. Social modelling may have utility in enhancing the effectiveness of many active medical treatments.     

A Multivariate Associative Finite Growth Mixture Modeling Approach Examining Adolescent Alcohol and Marijuana Use

Theoretical and empirical substance use development research suggests that adolescent populations are not homogenous and can often be separated into subpopulations characterized by qualitatively different patterns of substance use development. This paper demonstrates the application of a multivariate associative finite latent growth mixture modelling approach to examine heterogeneity in patterns of adolescent alcohol and marijuana use and the influence of age, gender, parent, and peer substance use. Substance use problem outcomes were also examined. Participants were male and female adolescents (N = 1,044) ranging in age from 11 to 17 years at the first assessment (Mean age = 14.47; SD = 1.95). Individuals were 45% female and 82% Caucasian. Using growth mixture methodology, a 7-class model captured distinct simultaneous alcohol and marijuana use patterns over a 3-year period. Findings highlight the importance of examining subgroups of adolescent substance use, rather than focusing only on single samples.     

小麦中烟曲霉生长温度与水分活度预测模型的建立

为快速预测和监控引起小麦霉变的烟曲霉的生长,在15～40℃温度及0.70～0.96水分活度下进行小麦储藏模拟实验,建立和验证烟曲霉D6生长的一级和二级预测模型。结果表明,一级生长模型中Bo-ltsmann模型优于Logistic模型。以Boltsmann模型拟合数据建立二级模型,采用平方根模型拟合,得烟曲霉D6的最低生长温度和水分活度分别为5.784℃和0.721。经验证,平方根模型能较好描述烟曲霉D6最大比生长速率与温度、水分活度之间的对应关系。     

生长激素对心血管系统的影响

生长激素（GH）是出生后主要刺激生长的激素,GH相当高比例的促生长作用是由胰岛素样生长因子-I（IGF—I）介导完成的。不同的代谢功能如碳水化合物和脂类代谢也受GH的直接影响。GH还对心血管及大脑有影响,本文拟对其分泌机制及作用和对心血管及大脑的影响作一综述。     

Quelles méthodes et quelle modélisation d’analyse de l’activité de travail de l’encadrement ? L’exemple de l’encadrement des chantiers de la construction

By referring to the ergonomic analysis of work and to the management sciences, the authors propose an analysis model of the managers’ activity. Until then, few researchs were realized in ergonomics science with this population which has to prepare and to organize the works of other operators. According to the authors, it is possible to apply to this population the model of “the centre de décision”. It allows to understand how their activity is determined by “upstream” centres and then how it determines the activity of centres “approval”. Applied to the project and site managers, this model brings solutions to transform their work and the work of the workmen.     

时间贴现的分段性

以延迟和相对延迟时间贴现的实验范式, 用选择法、匹配法确定价值主观相等点, 探讨时间贴现的分段性。三个实验和一个问卷调查发现, 时间贴现具有分段性。被试的时间贴现有三次显著变化, 表现为三个时段时间贴现心理状态的不同: 从现在到未来2周内规避损失、偏好风险、愿意短期等待, 从未来2周起直到未来10年采取非补偿性策略、需求与风险并重、愿意长期等待, 和从未来10年起直到未来50年规避风险、聊胜于无、不愿意等待。     

Impulsivity and reward sensitivity within the pen model: A test of discriminant hypotheses

Impulsivity and reward sensitivity are often treated as interchangeable constructs. This conflation may be traced back to Gray’s interpretation of impulsivity as the trait level manifestation of the Behavioral Activation System (BAS), that mediates sensitivity to rewards. In this study (N = 696) we evaluated discriminant hypotheses regarding the relationships between BAS-mediated reward sensitivity, impulsivity and Eysenck’s PEN superfactors. We hypothesized that reward sensitivity would be mainly linked with Extraversion, and that impulsivity would be primarily connected with Psychoticism. Hypotheses were tested using structural equation modelling and equality constraints tests. Results mostly supported our expectations: reward sensitivity was more strongly related to Extraversion than to the other PEN superfactors, while impulsivity was more strongly related to Psychoticism and Neuroticism. Implications for BAS and impulsivity research are discussed.