Executive functioning and prospective memory in young children

The current study examined the role of executive functioning (EF) in children's prospective memory (PM) by assessing the effect of delay and number of intentions to-be-remembered on PM, as well as relations between PM and EF. Ninety-six 4-, 5-, and 6-year-olds completed a PM task and two executive function tasks. The PM task required children to interrupt an ongoing card game to perform one action (single intention) or two actions (dual intention) with target cards after a short delay (1 min) or a long delay (5 min). There was no main effect of number of intentions or delay on the PM task. However, performance improved with age, and age and delay interacted such that 4-year-olds’ performance remained the same after a long delay whereas 5-year-olds’ performance improved after a long delay. We suggest that the age by delay interaction is a product of age differences in cognitive monitoring. Working memory but not inhibitory control predicted PM with age controlled. We argue that an executive function framework permits an integrative understanding of many processes involved in young children's prospective memory.     

TACE术联合自体CIK细胞治疗原发性肝癌

探讨肝动脉栓塞化疗（TACE）联合自体细胞因子诱导的杀伤细胞（CIK）治疗原发性肝癌的临床疗效。比较TACE术＋CIK组（治疗组）和TACE组（对照组）患者的免疫功能、临床疗效及副反应。结果表明,TACE术＋CIK与TACE术比较安全有效。因此,TACE术联合自体CIK细胞是治疗原发性肝癌的一种有效方法。     

孤独症的认知障碍研究及其评述

执行功能紊乱理论(Theory of Executive Dysfunction)、弱的中央统合理论(Weak Central Coherence theory)和心理理论假说(The Theory of Mind Hypothesis)是解释孤独症认知障碍的三种重要理论。本文着重通过回顾以往的实验研究来探讨三种理论的产生、发展及前进的方向, 以及三大理论之间的关系。三者可能从不同侧面诠释了孤独症认知障碍的机制, 如何综合起来更好地揭示孤独症的认知障碍和病理机制, 尚需深入和全面的研究。同时更多地考虑不同认知因素的交互影响以及研究的生态学效度, 可能是进一步研究需要考虑的问题。     

国外父母-孩子自传叙事研究现状及展望

父母-孩子自传叙事是指父母与孩子共同对过去发生的生活事件进行回忆和交流, 是实现自传记忆社会功能的一种重要形式。父母-孩子自传叙事的社会功能有教育和指导孩子、保持亲子亲密性等作用。在父母-孩子自传叙事的风格、结构和内容三个层面, 父母-孩子自传叙事对儿童认知发展、社会情感发展、自传记忆表征等方面有重要影响; 另外, 父母-孩子自传叙事中还存在有性别和社会、文化差异。未来的研究应注意线索词材料的类型以及与儿童心理理论发展、社会层次、纵向研究设计的结合。     

汉语学龄前儿童正字法意识的发展

本研究选择北京地区幼儿园3岁、4岁、5岁儿童各31、48、33名, 采用单部件意识测验和部件位置及功能意识测验系统探查了学龄前儿童的正字法意识各个层面的发展状况。单部件意识测验包括部件替换、部件缺失和部件旋转三个部分; 部件位置及功能意识测验分为假字和非字两个部分, 而非字又包括两形非字和形声非字。结果发现单部件意识测验中, 5岁组儿童在部件替换水平上的得分显著高于3岁组儿童, 而3岁组与4岁组、4岁组与5岁组儿童之间无显著差异; 部件缺失和部件旋转水平上, 三个年龄段的儿童的得分表现出明显的增长趋势。部件位置及功能意识测验中, 假字得分在三个年龄段之间无显著差异; 非字得分随年龄增长显著提高。这些结果表明, 单部件意识在学前期处于不断发展的阶段, 其中对部件替换的非字的拒绝能力发展较早, 部件缺失和部件旋转非字的拒绝能力发展较晚; 部件位置及功能意识在学前期已经开始发展, 3岁儿童已经具有假字符合正字法规则的认识, 但对非字违反部件位置合法性和功能完整性的认识直到4岁左右才开始萌芽, 5岁还未成熟。     

老年糖代谢异常患者血浆NT—proBNP与血管内皮功能早期监测意义

通过检测老年糖代谢异常患者的血浆N末端血清脑钠肽前体（NT—proBNP）水平与肱动脉血管内皮依赖性舒张功能（FMD）,探讨其早期监测意义。共77例观察对象,其中12例血糖正常的健康老人为对照组,65例老年糖代谢异常组患者根据空腹血糖（FBG）和糖耐量2小时（0GTT2h）血糖水平分为空腹血糖受损组（IFG）14例、糖耐量受损组（IGT）23例和2型糖尿病组（DM）28例。各组均检测血浆NT—proBNP水平和无创超声监测FMD。随着血糖代谢异常程度加重,比较正常组,糖代谢异常组的血浆NT—proBNP水平升高（P〈0．01）,FMD调节下降（P〈0．01）;糖代谢异常发展过程中,IFG阶段FMD即出现舒张失调（P〈0．05）;IGT阶段血浆NT-proBNP水平升高有意义并达到无症状心衰诊断标准（P〈0．01）,且FMD出现舒张过度调节,提示收缩和舒张功能双向调节不良。空腹血糖升高增加血管内皮依赖性舒张功能损害,当FBG合并（或）餐后血糖升高,血浆NT—proBNP水平升高可以成为早期预测慢性无症状心功能不全的危险因素。因此,关注老年糖代谢异常早期阶段进程,并联合血浆NT—proBNP水平和血管内皮依赖性舒张功能监测,不仅对靶器官保护具有早期预警意义,而且是临床控制血糖管理的重要而简易的方法之一。     

Art as Orientation

What is it that we lack in everyday life that causes us to value art so highly? This article argues that (almost) all values are to be understood in terms of a needs‐satisfaction system, and hence that the value of art can be understood only with reference to the state of the appreciator prior to engagement with the artwork. Aesthetic appreciation can be analysed as a process, which can be described in empirically based psychological terms, leading to a functional view of aesthetic experience as potentially enhancing the individual's orientation at sensory, cognitive, and interpersonal levels; our motivation is a special form of pleasure. Various objections are then considered, with particular attention to the role of pleasure in connection with tragedy; the relation of art to related cultural pursuits is also briefly indicated.     

记忆训练对改善少年、青年和老年人认知功能的作用

本工作采用“位置法”(method of loci)对24例少年、24例青年和22例老年被试进行了记忆训练研究。以毕生发展的观点比较认知训练对改善不同年龄人记忆的作用,进而探讨发展的认知功能储备能量的年龄差异和训练的迁移效应。结果表明认知干预措施可在一定程度上改善老年人的记忆,同时也显示了在发展的储能和对图形的迁移效应方面,老年人明显不如青、少年,而青年与少年则彼此相近。     

Effects of crystallization on corrosion resistance and electron work function of Zr65Al7.5Cu17.5Ni10 amorphous alloys

The effects of crystallization on the electron work function and corrosion resistance of Zr₆₅Al_7.5Cu_17.5Ni₁₀ amorphous alloys have been studied. The single-phase amorphous alloy exhibits a better corrosion resistance and has a higher work function than the partially and fully crystallized alloys with the same composition. The close relationship between corrosion resistance and work function indicates that the Kelvin probe technique can be a powerful tool for characterizing the corrosion behaviour of amorphous alloy on an electronic level.