The effects of massage velocity on heart rate and heart rate variability in healthy infants: A randomized crossover study

BackgroundInfant massage, in which mothers stroke their infant’s skin slowly and gently, can cause pleasant sensations in the infant that can be affected by the velocity of massage. However, the massage velocity at which infants feel the most pleasant sensations remains unclear.ObjectiveTo investigate the effects of massage velocity on heart rate (HR) and HR variability (HRV) in healthy infants.MethodTwenty-two infant-mother dyads two to seven months of age were recruited. Mothers stroked their infant’s skin at three massage velocities (5.0, 7.5, and 10.0 cm/s) in a randomized order for 15 min. The rhythm of massage velocity was calculated according to the length of three body areas. The massage velocity of the mothers was regulated using a metronome. HR and HRV (high frequency [HF] and low frequency [LF]) were measured at rest and during massage for each velocity. The effects on pleasantness were evaluated using percent change in median baseline value compared with median values for the three massage velocities. Statistical analysis was performed using analysis of variance mixed effect models to exclude “period” and “carryover” effects during massage.ResultsWhen measuring HF, massage (7.5 cm/s) caused a significant increase in pleasantness compared with 10.0 cm/s (p = 0.04). The HR and LF/HF ratio were not significantly changed between velocities.ConclusionResults of this study suggested that a massage velocity of 7.5 cm/s was the most pleasant for infants. Future research should investigate the relationship between an infant massage by optimal velocity and infant development in longitudinal studies.     

Gender detransition: a case study

Within the last decade, there has been a sharp global rise in the number of young people identifying as transgender. More recently, there appears to be an increase in the numbers of young people detransitioning or returning to identifying with their natal sex after pursuing medical transition. A case is presented of a young woman who pursued a gender transition and returned to identifying as female after almost two years on testosterone. The author considers and critiques the affirmative model of care for gender dysphoric youth in light of this case.     

SC-IAT范式下中学生良心的内隐性

目的:研究探讨了单类内隐联想测验(Single Category Implicit Association Test,SC-IAT)测量中学生良心的可行性,并分析内隐良心和外显良心的关系。方法:采用E-prime3.0软件编制SC-IAT良心测量程序,测量了中学生内隐良心; 采用青少年良心问卷测量了中学生的外显良心,并运用相关技术分析两者之间的关系。结果:SC-IAT实验中,中学生良心的内隐效应显著,且不存在性别、独生与否、学段、家庭结构、家庭所在地等人口统计学指标上的显著差异; 内隐良心与外显良心之间的相关不显著。结论:(1)中学生良心存在积极内隐效应;(2)外显良心和内隐良心相互分离,是两个不同的建构。     

自然数码奇象记忆法记忆复杂数字的神经机制

本研究采用学习-再认范式和复杂数字记忆材料,考察自然数码奇象记忆法相对于机械记忆法在记忆提取上的优势及神经机制。行为结果表明,自然数码奇象记忆法比机械记忆法的再认准确率更高。事件相关电位分析结果显示,再认提取阶段奇象记忆条件下诱发的N400和N700波幅显著更低,这说明奇象记忆提取更容易。在自然数码奇象记忆条件下,正确再认旧数字诱发的前额区、左顶枕叶区及中顶枕叶区N700成分与使用自然数码奇象记忆有关。本研究表明,采用自然数码奇象记忆可以减少或跨越语义加工,从而提高个体对材料的记忆效率。     

Evaluating pedestrian interaction preferences with a game theoretic autonomous vehicle in virtual reality

Localisation and navigation of autonomous vehicles (AVs) in static environments are now solved problems, but how to control their interactions with other road users in mixed traffic environments, especially with pedestrians, remains an open question. Recent work has begun to apply game theory to model and control AV-pedestrian interactions as they compete for space on the road whilst trying to avoid collisions. But this game theory model has been developed only in unrealistic lab environments. To improve their realism, this study empirically examines pedestrian behaviour during road crossing in the presence of approaching autonomous vehicles in more realistic virtual reality (VR) environments. The autonomous vehicles are controlled using game theory, and this study seeks to find the best parameters for these controls to produce comfortable interactions for the pedestrians. In a first experiment, participants’ trajectories reveal a more cautious crossing behaviour in VR than in previous laboratory experiments. In two further experiments, a gradient descent approach is used to investigate participants’ preference for AV driving style. The results show that the majority of participants were not expecting the AV to stop in some scenarios, and there was no change in their crossing behaviour in two environments and with different car models suggestive of car and last-mile style vehicles. These results provide some initial estimates for game theoretic parameters needed by future AVs in their pedestrian interactions and more generally show how such parameters can be inferred from virtual reality experiments.     

Plus de contention ni d’isolement sans contrôle du juge judiciaire

Although of old and common use, the use of isolation and restraint in psychiatry was not regulated until 2016 with the creation of article L. 3222-5-1 of the Public Health Code. However, the Court of Cassation considered that, as a form of care, it was beyond the office of the liberty and custody judge to controle its implementation. Questioned by a plea of unconstitutionality submitted by the Court of Cassation, the Constitutional Council considered, with its decision of 19 June 2020, that these measures constituted a deprivation of liberty requiring judicial review at short notice. The Sages thus declare the provisions of article L. 3222-5-1 unconstitutional, with delayed effect as of December 31, 2020, requiring legislator to rethink and organise the supervision and control of decisions of restraint and isolation.     

Le vaccin,un médicament devenu l’arme absolue promise contre la COVID-19 : une réglementation adaptée ?

As the first vaccines against COVID-19 arrive on the market, the question of the safety of these products arises in the public debate. The major concern is about the possible occurrence of adverse effects, particularly in the context of the use of novel pharmaceutical technologies such as mRNA. It is important to remind both patients and professionals that a vaccine is not only a medicinal product in its own right, but also a special medicinal product: biological and immunological. As a result, its supervision is draconian, and despite the urgency, no requirements have been lowered. The speed of marketing is the result both of adapted clinical trials and optimized evaluation procedures.     

Investigating temporal variations in pedestrian crossing behavior at semi-controlled crosswalks: A Bayesian multilevel modeling approach

“Semi-controlled” crosswalks are unsignalized, but have clear pavement markings and “yield to pedestrian” signs. At these locations, pedestrians and motorists frequently interact to determine who should proceed first. When interacting with drivers, pedestrian crossing decisions are complex events that involve a variety of human responses, as well as vehicle dynamics, traffic characteristics, and environmental conditions. In addition, these complexities can be subject to temporal effects. Without considering temporal variations in pedestrian-motorist interaction, statistical methods could lead to biased coefficient estimates and inaccurate conclusions.The study developed a Bayesian multilevel logistic regression (BMLR) model to capture heterogeneities in pedestrian interaction behavior during four different time periods. The proposed method incorporates time-specific effects that vary randomly between time-periods based on a weakly informative prior. The results indicate significant factors, some of which confirm previous research and some that are new ways to explain pedestrian behavior at the individual level. The identification of variables such as FlowOn and FlowWait sheds light on the interactions between pedestrians – providing more information than the single GroupSize measure.Some consequent safety implications are discussed from the perspectives of vehicle dynamics, vehicle flow rate and pedestrian volume. The more detailed metrics developed in this paper will provide a valuable starting point. for the design of crosswalk controls that will foster a higher degree of compliance and less delay.     

Athlete perspectives on the enablers and barriers to nutritional adherence in high-performance sport

ObjectivesPoor adherence to nutritional guidance by athletes may compromise their health and performance. Enhancing adherence is therefore an important performance and welfare strategy. The aim of this study was to qualitatively explore the barriers and enablers of elite athletes' adherence to nutritional guidelines.DesignUnderpinned by our constructionist epistemological position and our relativist ontology, we conducted a qualitative study using focus groups.MethodsWe used the Capability, Opportunity, and Motivation Behaviour (COM-B) model and the Theoretical Domains Framework (TDF) to conduct focus group discussions with a purposive sample of 39 UK-based funded athletes (mean age = 23 ± 3.81), participating in either Olympic and Paralympic sport (n = 30) or professional sport (n = 9), who had access to a nutritionist. Data were analysed using reflexive thematic analysis.ResultsAthlete adherence to nutritional guidance was seasonal and included inadequate energy intakes and episodes of binge eating. Underpinning these behaviours, athletes' emotional barriers (motivation) are reinforced through their social interactions within the high-performance environment (opportunity) and athletes' training environment limits developmental opportunities for food planning (capability). However, a holistic-developmental approach by the sports nutritionists (opportunity) supports athlete wellbeing and nutritional adherence.ConclusionThese findings advance theoretical understanding of the barriers and enablers of nutritional adherence amongst elite-level athletes in high-performance sport and present a number of significant implications for athlete support personnel seeking to enhance performance in demanding sporting contexts. Drawing on the Behaviour Change Wheel (BCW), recommendations include the need to 1) train and educate sports nutritionists in human behaviour, 2) update regulations for sports nutrition profession practice to acknowledge the skills required to support athletes' emotional wellbeing, 3), educate coaches on the sensitivity of body weight and composition and develop guidelines for monitoring athletes' body weight and composition in sport, 4) persuade influential leaders to develop culture guidelines that shift the performance-narrative of high-performance (i.e., environmental restructuring).     

γ节律神经振荡：反映自闭症多感觉整合失调的一项重要生物指标

多感觉整合是对不同感官信息进行选择、联系、统一乃至解释的加工过程, 它需要神经系统不同功能区域的共同投入与相互协调, 以实现多种感觉信息的时间捆绑以及全局性的预测编码。而γ神经振荡因具有反映神经皮层兴奋/抑制的平衡状况, 实现多感官信息的时间同步, 以及通过跨频耦合实现全局性预测编码的特点, 在多感觉整合的加工过程中发挥着重要作用。相比正常个体, 自闭症患者神经系统中的GABA中间神经元存在结构与功能异常, 导致γ神经振荡紊乱, 由此破坏了正常的时间同步以及预测编码加工, 并最终引发多感觉整合失调。基于上述因果关联, 未来研究可结合无创可逆性干预技术, 以γ节律神经振荡为生物反馈指标, 形成科学系统化的临床干预治疗方案。