The cortisol awakening response and the big five personality dimensions

The present study investigated the association between the big five personality dimensions and the cortisol awakening response (CAR), a physiological parameter reflective of HPA axis activity. One hundred and seven participants completed the big five inventory (BFI; John, Donahue, & Kentle, 1991) and collected salivary cortisol samples at 0, 30, and 60 min after awakening on a weekday morning. The cortisol awakening response under the curve (CARauc) and the cortisol awakening response with respect to increase (CARi) were used as outcome variables in the statistical analyses. Hierarchical linear regression analyses were conducted using the data of 92 participants. Gender and age were included as covariates in block one of the regressions, followed by the personality dimensions in block two. Extraversion emerged as a significant predictor of CARauc. No other personality dimensions were significantly predictive of CARauc or CARi. Interestingly, gender emerged as the strongest predictor in the CARauc, with females exhibiting greater cortisol release across the awakening period than males. Our results suggest that extraversion and gender may be particularly important variables to consider in the regulation of the HPA axis.     

执行意向对目标达成的促进及其作用过程

执行意向,也被称为“如果—那么”计划,是指将一个预期的情境与一个确定的目标定向行为联系起来,明确说明了个体在什么时间、地点以及如何追求一个特定目标的计划.大量的实验室和现场实验研究发现,执行意向能有效促进目标的达成.执行意向中“如果”成分使得预期情境线索的心理表征高度激活;而“那么”成分使得计划中的反应得以自动实施.这两个假设的认知过程已被证实,并且在执行意向影响目标达成过程中起到中介作用.在未来的研究中除了将其与动机理论进行整合以及更深入地去探讨其心理机制之外,还要积极进行本土化的实证研究.     

On Chimeras

This essay is a critical response to Neville Cobbe's article “Cross‐Species Chimeras: Exploring a Possible Christian Perspective.” New technologies, particularly biotechnologies, raise major concerns in society. In the absence of good ethical thinking on these issues, bad ethical thinking becomes regnant. Two common types of bad ethical thinking are (1) confusing whatever disturbs people with genuine ethical issues and (2) confusing religious issues with ethical ones. Cobbe's article commits the former type of error with regard to the possibility of a mouse created with human brain neurons. I analyze and discuss that error and also raise questions about Cobbe's attempt to analyze the creation of chimeras from a Christian perspective.     

THE USE OF RESPONSE PREVENTION TO ELIMINATE NOCTURNAL THUMBSUCKING

The effects of a response prevention strategy consisting of the fading of restraint and the removal of reinforcers on nocturnal thumbsucking behavior was evaluated in four experiments. In the first experiment, nocturnal thumbsucking was restrained for approximately 1 week by having each of two boys wear a boxing glove to bed. Next they wore absorbent cotton over the thumb for 11 nights. During the last phase in this condition, they wore a fingertip bandage over the thumb for 10 to 11 nights. The response prevention package completely eliminated thumbsucking behavior in both boys. In the second experiment, the removal of reinforcers alone for nocturnal thumbsucking had little or no effect on the thumbsucking behavior of three girls whereas the later introduction of the entire package completely suppressed thumbsucking in all three girls. In the third experiment, the package was evaluated in the absence of the glove restraint condition. The results showed that the treatment package was effective in the absence of the glove restraint condition for all three children. The final experiment examined whether the package could be effective if the absorbent cotton condition was abruptly removed without using the fingertip bandage condition. The results showed the treatment to be effective with one of two boys, but not the other.     

腹部手术后舒芬太尼持续硬膜外镇痛与静脉镇痛的比较

采用双盲、前瞻性研究,在 60例年龄30岁～50岁,ASAⅠ-Ⅱ级,BMI（Body mass index体重指数）＜30kg/m^2,择期行下腹部手术患者中施行舒芬太尼术后镇痛。随机分为2组：硬膜外镇痛组（E组）和静脉镇痛组（Ⅰ组）,比较舒芬太尼术后持续静脉输注与静脉输注的半数有效浓度及副作用。结果显示E组舒芬太尼持续硬膜外输注的EC50（median effective concentration 半数有效浓度）为0.87μg/ml,95%的可信区间为0.79μg/ml～0.96 μg/ml ;Ⅰ组舒芬太尼持续静脉输注的EC50为0.63μg/ml,95%的可信区间为0.55μg/ml～0.70μg/ml ;恶心、呕吐、皮肤瘙痒发生率两组相似,Rammsay评分Ⅰ组＞E组。因此,舒芬太尼持续静脉输注的效价大于硬膜外输注,而硬膜外输注镇痛呼吸抑制副作用更少;并推测椎管内应用舒芬太尼主要作用部位仍在脊髓以上中枢。     

Graded response model based on the logistic positive exponent family of models for dichotomous responses

Samejima (Psychometrika 65:319–335, 2000) proposed the logistic positive exponent family of models (LPEF) for dichotomous responses in the unidimensional latent space. The objective of the present paper is to propose and discuss a graded response model that is expanded from the LPEF, in the context of item response theory (IRT). This specific graded response model belongs to the general framework of graded response model (Samejima, Psychometrika Monograph, No. 17, 1969 and No. 18, 1972; Handbook of modern item response theory, Springer, New York, 1997; Encyclopedia of Social Measurement, Academic Press, San Diego, 2004), and, in particular to the heterogeneous case (Samejima, Psychometrika Monograph, No. 18, 1972). Thus, the model can deal with any number of ordered polytomous responses, such as letter grades (e.g., A, B, C, D, F), etc. For brevity, hereafter, the model will be called the LPEF graded response model, or LPEFG. This model reflects the opposing two principles contained in the LPEF for dichotomous responses, with the logistic model (Birnbaum, Statistical theories of mental test scores, Addison Wesley, Reading, 1968) as their transition, which provide a reasonable rationale for partial credits in LPEFG, among others.