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11.
Natsuko Ikeda Shinichi Yamada Kasumi Yasuda Shinya Uenishi Atsushi Tamaki Takuya Ishida Michiyo Tabata Tomikimi Tsuji Sohei Kimoto Shun Takahashi 《Journal of Neuropsychology》2023,17(2):351-363
Cognitive impairment in schizophrenia and other psychiatric disorders is a challenge to be overcome in order to maintain patients' quality of life and social function. The neurological pathogenesis of cognitive impairment requires further elucidation. In general, the hippocampus interacts between the cortical and subcortical areas for information processing and consolidation and has an important role in memory. We examined the relationship between structural connectivity of the hippocampus and cortical/subcortical areas and cognitive impairment in schizophrenia, major depressive disorder and bipolar disorder. Subjects comprised 21 healthy controls, 19 patients with schizophrenia, 20 patients with bipolar disorder and 18 patients with major depressive disorder. Diffusion-weighted tensor images data were processed using ProbtrackX2 to calculate the structural connectivity between the hippocampus and cortical/subcortical areas. Cognitive function was assessed using the Brief Assessment of Cognition in schizophrenia composite score. Hippocampal structural connectivity index was significantly correlated with composite score in the schizophrenia group but not in the healthy control, major depressive disorder or bipolar disorder groups. There were no statistically significant differences in hippocampal structural connectivity index between the four groups. Structural connectivity between the hippocampus and cortical/subcortical areas is suggested to be a pathophysiological mechanism of comprehensive cognitive impairment in schizophrenia. 相似文献
12.
Thomas Nemeth 《Studies in East European Thought》1995,47(3-4):155-177
13.
Herman J. Woltring 《Human movement science》1985,4(3):229-245
Estimating derivatives from noisy displacement data is a notoriously ill-posed problem in signal processing and biomechanics. Following the work of Wood and Jennings (1978) and Hatze (1979, 1981), the present paper describes the use of optimally regularized, natural quintic splines for estimating smoothed positions, velocities, and accelerations from equidistantly sampled, noisy position measurements. It appears that the nature of the boundary conditions of the data is of some importance, since various algorithms used hitherto result in artefacts throughout the data if the true derivatives at the record ends differ significantly from zero. Natural quintic splines do not suffer from this disadvantage below the third derivative.The ill-posed character of movement analysis has some interesting implications for movement synthesis and optimization, similar to the indeterminacy of muscular co-contraction from merely external, biomechanical measurements. 相似文献
14.
A study was conducted to examine the relation between each of several attitudinal qualities and attitude-behavior consistency. Subjects' attitudes toward volunterring to participate in psychological research were assessed. The number of experiments in which each subject volunteered to participate was employed as the measure of behavior. Attitude-behavior consistency was significantly related to (1) the amount of direct experience upon which the subject's attitude was based (specifically, the number of experiments in which the subject had previously participated), (2) the degree of certainty with which the attitude was held, and (3) how well-defined the subject's attitude was, as measured by the width of his latitude of rejection. These three attitudinal qualities were significantly intercorrelated, suggesting that direct experience with an attitude object may produce an attitude that is both better defined and more confidently held than an attitude formed through more indirect means. 相似文献
15.
Joseph A. Corcoran 《Journal of Fluency Disorders》1980,5(2):99-114
This study investigated the effects of presumably positive and neutral response-contingent stimuli on the occurence of stuttering. Eight adult stutterers spoke spontaneously during a 60-min experimental session, which was divided into three 20-min periods. During Condition I no stimuli were delivered. During Condition II a digital counter and a pair of yellow lights were activated each time the subject stuttered. During Condition III these same response-contingent stimuli were delivered, but with the additional factor that the subject would earn 5¢ each time the counter moved forward and the lights were illuminated. Conditions II and III were counterbalanced across subjects. The experimenter was unaware of which of the two contingencies were operative during Conditions II and III. Results showed no significant changes in occurence of stuttering due to either response-contingent stimulus. A discussion of theoretical and experimental implications is given. 相似文献
16.
17.
Gary L Wells 《Journal of experimental social psychology》1980,16(1):47-60
It was proposed that people attribute an individual's behavior more to internal factors when that individual's actions are influenced by reward than when those actions are influenced by punishment. Previous research has failed to control for the power of reward versus punishment which, in effect, creates a confounding of behavioral base rates (consensus) with the reward-punishment manipulation. The current research created reward and punishment contingencies that were equal in their base rates for producing a compliant response. In Experiment 1, subjects (n = 63) who produced the base-rate data also made attributions regarding a compliant target person. The results supported the reward-punishment attributional asymmetry hypothesis in that the target person was held more responsible for his actions in the reward than in the punishment conditions. A second experiment (n = 72) provided some attributors with information regarding base rates for compliance and measured perceived base rates for compliance. Knowledge of the base rates for compliance eliminated the reward-punishment attributional asymmetry phenomenon. Subjects not provided with such knowledge erroneously assumed different base rates for reward and punishment and maintained the perception of reward-punishment attributional asymmetry. Using subjects' estimates of base rate for compliance as a covariate eliminated the attributional asymmetry effect. It is suggested that erroneous base-rate assumptions mediate the attributional asymmetry phenomenon. 相似文献
18.
Douglas S. Grant 《Learning and motivation》1980,11(3):339-354
The effect of contextual stimuli on proactive interference in the rat was investigated in three experiments. The task was a modified delayed alternation procedure in which the rat was initially forced to one side of a T maze (the interfering forcing) followed by a forcing to the opposite side (the target forcing). A free choice run followed the target forcing in which a turn in either direction could be made. In order to obtain reinforcement on the free choice run, the rat was required to turn in the direction opposite that of the target forcing (i.e., in the same direction as the interfering forcing). Manipulation of the context prevailing during the interfering forcing, target forcing, and free choice runs revealed that free choice accuracy was (a) greater when the interfering and target forcings were conducted in different contexts than when they were conducted in the same context and (b) influenced only slightly, if at all, by whether the free choice context coincided with that prevailing during the interfering forcing or with that prevailing during the target forcing. 相似文献
19.
Experiments 1 and 2 examined the effects of various durations of lickcontingent delays of reinforcement on the development of schedule-induced polydipsia. Food was provided every 1 min in the absence of licking. Delays of 1 min or more effectively disrupted the development of the licking behavior. In Experiments 3 and 4 a lick-contingent stimulus was provided in addition to the delay of food delivery. A light, which was turned on by a lick and turned off by food, greatly enhanced the development of polydipsia under delays that had previously prevented such development. A tone proved less effective than the light in promoting the development of polydipsia. Adventitious reinforcement and conditioned punishment explanations of these results were considered. A distinction was drawn between the mechanism responsible for the development of schedule-induced behavior and that responsible for its maintenance. 相似文献
20.
The asymmetry of the posterior Sylvian branches of the middle cerebral artery was examined on the carotid angiograms of 59 patients in whom the lateralization of speech representation was known from sodium amobarbital (Amytal) studies. The usual asymmetry of these vessels was found to be present in the group of patients with left-hemisphere speech representation but significantly reduced in patients with atypical cerebral dominance for speech. A model of the inheritance of handedness and cerebral dominance is extended to take account of these results. 相似文献