Cooperation or Tension? Dyadic Coping in Cystic Fibrosis

Following a rise in the life expectancy of cystic fibrosis (CF) patients, many adults with CF form couple relationships. Yet, dyadic coping has not been previously examined in people with CF. This study examined how adults with CF and their partners cope as a couple with the illness, and what meanings each partner and the couple as a unit attribute to the experience. Seventeen adult CF patients and their partners participated in separate semi‐structured in‐depth interviews. Two main patterns of dyadic coping with CF were identified as follows: cooperation and tension. For couples in cooperation, the marital relationship served as a resource for adaptive coping. These couples were characterized by similarities in their perception of the place of CF in their lives and of their roles in the marital relationship. Couples in tension described the couple relationship as strained by difficulty of accepting the disease, proliferation of negative emotions, and a sense of burden and loneliness in the process of coping. Findings point to the importance of mutual empathy, clear and accepted division of roles between the partners, and open communication for facilitating coping as a couple.     

Maintenance of Relationship and Individual Functioning Gains Following Online Relationship Programs for Low‐Income Couples

Initial evidence suggests that gains in relationship functioning from brief, web‐based programs are maintained through one year following the intervention; however, whether these results generalize to a low‐income sample is unclear. Furthermore, previous research from in‐person couple therapy suggests there may be different shapes of maintenance slopes for behavioral versus acceptance‐based techniques. This study contacted 668 individuals who enrolled in online behavioral (ePREP) or acceptance‐based (OurRelationship) programs one year following completion of the program. Multilevel modeling was used to examine linear and quadratic rates of change in the year following the online intervention as well as total amount of change from pretreatment to 12‐month follow‐up for both relationship and individual functioning. The majority of couples who responded continued to be in a relationship with the same partner (68.3%). Examinations of relationship functioning indicated couples in both programs maintained their gains over follow‐up (i.e., no significant linear or quadratic changes), with medium‐to‐large within‐group effect sizes from pre‐ to one‐year follow‐up. There were no significant differences in relationship outcomes between OurRelationship and ePREP. Similarly, examinations of individual functioning outcomes indicated couples maintained their gains over follow‐up or continued to improve. In total, couples experienced small‐to‐medium within‐group effect sizes from pretreatment to one‐year follow‐up, with larger effects for individuals who were initially distressed. These results suggest that online programs create lasting change for low‐income couples in relationship and individual functioning, with minimal differences between behavioral and acceptance‐based orientations.     

Different level automation technology acceptance: Older adult driver opinion

The increase in the number of older adult drivers in developed countries has raised safety concerns due to the decline in their sensory, motor, perceptual, and cognitive abilities which can limit their driving capabilities. Their driving safety could be enhanced by the use of modern Automated Driver Assistance Systems (ADASs) and might totally resolved by full driving automation. However, the acceptance of these technologies by older adult drivers is not yet well understood. Thus, this study investigated older adult drivers’ intention to use six ADASs and full driving automation through two questionnaires with 115 and 132 participants respectively in Rhode Island, USA. A four-dimensional model referred to as the USEA model was used for exploring older adult drivers’ technology acceptance. The USEA model included perceived usefulness, perceived safety, perceived ease of use, and perceived anxiety. Path Analysis was applied to evaluate the proposed model. The results of this study identified the important factors in older adult drivers’ intention to use ADASs and full driving automation, which could assist stakeholders in improving technologies for use by older drivers.     

Effects of D- and L-amphetamine on the predatory behavior of Southern grasshopper mice,onychomys torridus

Adult male and female southern grasshopper mice (Onychomys torridus) were tested for predatory aggression toward cricket prey 1 hr after single injections of d-amphetamine (1 or 10 mg/kg) or 1-amphetamine (1 or 10 mg/kg). At the lower dose, d-amphetamine decreased feeding behaviors, while I-amphetamine altered attack-related behaviors. At the higher dose, both stereoisomers appeared to be equipotent in significantly decreasing 5 measures of predatory aggression. These results suggest that brain dopamine and norepinephrine play important roles in the regulation of predatory aggression of Onychomys torridus.     

Minimal experience required for immediate-early gene induction in zebra finch neostriatum

We show that a single presentation of a zebra finch song, 2 s in duration, will induce an "immediate-early gene" response in the caudomedial neostriatum of zebra finches (Poephila guttata). Repetition of this stimulus 10 times is sufficient to induce a maximal increase in RNA and protein, detected 30 and 90 min later respectively. Thus very brief stimuli can set in motion a slow genomic process in the brain which takes hours to resolve. Immediate-early gene function is often considered in the context of a "feedback" model (i.e., to consolidate memories of the inducing event). However, based on the long lag observed here between initiation and full expression of the molecular response, we suggest an alternative, ethologically based, "feed-forward" model in which exposure to a novel or significant context triggers an increase in the efficiency of memory capture processes for subsequent experiences.     

Genetic Counseling for Fragile X Syndrome: Updated Recommendations of the National Society of Genetic Counselors

These recommendations describe the minimum standard criteria for genetic counseling and testing of individuals and families with fragile X syndrome, as well as carriers and potential carriers of a fragile X mutation. The original guidelines (published in 2000) have been revised, replacing a stratified pre- and full mutation model of fragile X syndrome with one based on a continuum of gene effects across the full spectrum of FMR1 CGG trinucleotide repeat expansion. This document reviews the molecular genetics of fragile X syndrome, clinical phenotype (including the spectrum of premature ovarian failure and fragile X-associated tremor-ataxia syndrome), indications for genetic testing and interpretation of results, risks of transmission, family planning options, psychosocial issues, and references for professional and patient resources. These recommendations are the opinions of a multicenter working group of genetic counselors with expertise in fragile X syndrome genetic counseling, and they are based on clinical experience, review of pertinent English language articles, and reports of expert committees. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. The professional judgment of a health care provider, familiar with the facts and circumstances of a specific case, will always supersede these recommendations.     

Predictive Genetic Testing for Hereditary Breast and Ovarian Cancer: Psychological Distress and Illness Representations 1 Year Following Disclosure

This prospective study evaluates emotional functioning and illness representations in 68 unaffected women (34 carriers/34 noncarriers) 1 year after predictive testing for BRCA1/2 mutations when offered within a multidisciplinary approach. Carriers had higher subjective risk perception of breast cancer than noncarriers. Carriers who did not have prophylactic oophorectomy had the highest risk perception of ovarian cancer. No differences were found between carriers and noncarriers regarding perceived seriousness and perceived control of breast and ovarian cancer. Mean levels of distress were within normal ranges. Only few women showed an overall pattern of clinically elevated distress. Cancer-specific distress and state-anxiety significantly decreased in noncarriers from pre- to posttest while general distress remained about the same. There were no significant changes in distress in the group of carriers except for ovarian cancer distress which significantly decreased from pre- to posttest. Our study did not reveal adverse effects of predictive testing when offered in the context of a multidisciplinary approach.     

The Ethics of Type 1 Diabetes Prediction and Prevention Research

There are approximately one million cases oftype 1 diabetes in the US, and the incidenceis increasing worldwide. Given that two-thirdsof cases present in childhood, it is criticalthat prediction and prevention research involvechildren. In this article, I examine whethercurrent research methodologies conform to theethical guidelines enumerated by the NationalCommission for the Protection of Human Subjectsof Biomedical and Behavioral Research, andadopted into the federal regulations thatprotect research subjects. I then offer twopolicy recommendations to help researchersdesign studies that conform to these ethicalrequirements.