Is there an alternative cerebral network associated with enhanced phonological processing in deaf speech-users? An exceptional case

Most people born deaf and exposed to oral language show scant evidence of sensitivity to the phonology of speech when processing written language. In this respect they differ from hearing people. However, occasionally, a prelingually deaf person can achieve good processing of written language in terms of phonological sensitivity and awareness, and in this respect appears exceptional. We report the pattern of event-related fMRI activation in such a deaf reader while performing a rhyme-judgment on written words with similar spelling endings that do not provide rhyme clues. The left inferior frontal gyrus pars opercularis and the left inferior parietal lobe showed greater activation for this task than for a letter-string identity matching task. This participant was special in this regard, showing significantly greater activation in these regions than a group of hearing participants with a similar level of phonological and reading skill. In addition, SR showed activation in the left mid-fusiform gyrus; a region which did not show task-specific activation in the other respondents. The pattern of activation in this exceptional deaf reader was also unique compared with three deaf readers who showed limited phonological processing. We discuss the possibility that this pattern of activation may be critical in relation to phonological decoding of the written word in good deaf readers whose phonological reading skills are indistinguishable from those of hearing readers.     

The logic of how-questions

Philosophers and scientists are concerned with the why and the how of things. Questions like the following are so much grist for the philosopher’s and scientist’s mill: How can we be free and yet live in a deterministic universe?, How do neural processes give rise to conscious experience?, Why does conscious experience accompany certain physiological events at all?, How is a three-dimensional perception of depth generated by a pair of two-dimensional retinal images?. Since Belnap and Steel’s pioneering work on the logic of questions, Van Fraassen has managed to apply their approach in constructing an account of the logic of why-questions. Comparatively little, by contrast, has been written on the logic of how-questions despite the apparent centrality of questions such as How is it possible for us to be both free and determined? to philosophical enterprise.¹ In what follows I develop a logic for how-questions of various sorts including how-questions of cognitive resolution, how-questions of manner, how-questions of method, of means, and of mechanism.     

Are errors differentiable from deceptive responses when feigning memory impairment? An fMRI study

Previous neuroimaging studies have suggested that the neural activity associated with truthful recall, with false memory, and with feigned memory impairment are different from one another. Here, we report a functional magnetic resonance imaging (fMRI) study that addressed an important but yet unanswered question: Is the neural activity associated with intentional faked responses and with errors differentiable? Using a word list learning recognition paradigm, the findings of this mixed event-related fMRI study clearly indicated that the brain activity associated with intentional faked responses was different to the activity associated with errors committed unintentionally. For intentional faked responses, significant activation was found in the ventrolateral prefrontal cortex, the posterior cingulate region, and the precuneus. However, no significant activation was observed for unintentional errors. The results suggest that deception, in terms of feigning memory impairment, is not only more cognitively demanding than making unintentional errors but also utilizes different cognitive processes.     

视觉选择性注意脑机制研究进展

视觉选择性注意一直是认知心理学的研究热点之一。注意的早晚期选择问题和基于空间与基于客体的选择问题是选择性注意研究中长期争论的两大理论问题。脑成像研究不仅为解决这些争论提供了有力的证据 ,而且深化和拓展了这两大问题的研究。该文介绍了脑成像研究在上述两个领域的主要研究成果 ,并展望了今后相关问题的研究重点。     

Using a System of Least Prompts Procedure to Teach Telephone Skills to Elementary Students with Cognitive Disabilities

Using the telephone to contact others can be an important skill in maintaining friendships with peers. This investigation used a system of least prompts (SLP) procedures to teach two telephone skills to 3 elementary students with cognitive disabilities: (a) placing phone calls and (b) leaving recorded voicemail messages. The SLP procedure was effective in teaching both skills to all 3 students. Results for maintenance and generalization, however, were mixed. This investigation was completed to partially satisfy the thesis requirement for a Master’s degree at the University of Kentucky.     

聋人早期手语经验对脑功能及结构的塑造作用

语言经验对脑功能和结构发展有重要的塑造作用。然而, 目前的相关证据主要来自对脑损伤导致的失语症病人的语言康复、第二语言学习以及针对成人读者进行的语言训练等方面的研究。幼儿时期的早期语言经验对脑结构与功能发展的影响更加重要, 但直接的研究证据却相当缺乏。本文提出一个研究设想, 拟综合使用多种脑成像技术, 系统探讨有早期手语经验和无早期手语经验的聋人个体在脑皮层语言功能的组织及脑结构发育的差异, 包括语言任务中大脑语言区的激活模式, 静息状态下脑功能联结的默认网络特征, 脑皮层灰质密度, 以及神经纤维束发育状况等, 揭示早期语言经验对大脑功能和结构发育的塑造作用。     

多目标追踪的神经机制

多目标追踪任务是研究动态场景中视觉注意加工机制常用的范式。自1998年开始对多目标追踪神经机制的影像学研究以来, 研究者采用ERP和fMRI等技术对多目标注意追踪所涉及的神经电生理活动和脑功能区激活方面开展了大量研究。ERP研究发现, 追踪过程持续的ERP脑电成分如N2pc、CDA的波幅与注意追踪负荷有关, 并且出现在目标与非目标上的探测刺激诱发的脑电成分如N1、P1波幅的差异可反映注意资源的分配, 具体为目标在追踪过程中得到了激活, 而非目标受到了抑制。fMRI研究比较一致地发现了顶叶(包括前顶内沟、后顶内沟、顶上小叶)、背外侧额叶皮层等在注意追踪中的强烈激活。其中顶内沟主要与注意负荷有关, 顶内沟的活动水平直接决定了观察者注意追踪的行为表现。而顶上小叶可能更多的负责注意转移。背外侧额叶皮层可能负责追踪时的感觉运动预测过程。     

A neurodevelopmental perspective on male violence

Research is increasingly documenting a neurobiological basis to violence. This review takes a neurodevelopmental perspective on the very small group of males who grow up to become persistent violent offenders. After outlining six criteria for what constitutes a neurodevelopmental disorder, the extent to which chronic violence meets these definitional criteria is examined, covering the fields of genetics, structural and functional brain imaging, and neuropsychology. Early health risk factors for violence are then outlined, including birth complications, minor physical anomalies, prenatal smoking and alcohol exposure, poor nutrition, lead exposure, and traumatic brain injury. Persistent adult violence is argued to originate in aberrant temperamental behavior in early childhood, to have a stable developmental trajectory, and to be associated with impaired education, social, and occupational functioning. Taken together, it is argued that chronic adult violence meets criterion for being conceptualized as having neurodevelopmental origins and that an important, but not sole, source of neural maldevelopment lies in prenatal and early postnatal risk factors. This review concludes with a recognition of the sociopolitical context within which a neurodevelopmental perspective on chronic violence sits, together with directions for future research, including whether a neurodevelopmental hypothesis is best applied to reactive as opposed to proactive aggression.     

句法加工的脑机制

语言理解中,句法加工至关重要,它把各个意义单元以不同的方式整合起来,从而形成整体的意义表征。句法加工的脑机制是心理语言学比较关注的问题,目前由于ERP技术和功能成像技术的进步,使对这一机制的探讨成为可能。该文对有关句法加工的脑机制的研究进行了回顾与总结,并针对目前该领域存在的问题与争论进行了讨论