Associations Among Anxiety Disorders and Non-anxiety Disorders,Functional Impairment and Medication in Children and Adolescents

This is a study of comorbid anxiety disorders and how they affect the clinical picture of comorbid cases. The sample consisted of 576 Spanish children aged 8 to 17 years receiving psychiatric outpatient consultation that were evaluated using a semi-structured diagnostic interview for both parents and children. A specific association of homotypic comorbidity among anxiety disorders that was independent of the presence of other disorders was found. There was heterotypic comorbidity between anxiety and depressive disorders, ADHD, anorexia and tic disorders. Relationships between non-anxiety disorders were, in general, independent of anxiety, but anxiety moderated the relationship between ADHD-Conduct disorder and Conduct disorder-enuresis. Comorbid anxiety increased difficulties in social interaction, was related with higher global impairment and had an impact on consultation and medication. Anxiety disorder comorbidity should be well recognized in order not to disregard the treatment of all present disorders.     

Efficient search under constraints and not working memory resources supports creative action emergence in a convergent motor task

Creative (original and functional) solutions to problems can be facilitated by guiding search behavior. According to cognitive models, when solving convergent tasks (tasks with few solutions), high available working memory (WM) resources and capacity can guide creative solution emergence via repeated (persistent) search within a solution subcategory. However, no clear associations have been found of WM capacity on creative outcomes when tasks require the individual to enact solutions in divergent doing tasks. This study further tested constraints on WM resources on search behavior and creative outcomes in a convergent doing task. Novices to combat sports were asked to repeatedly strike a target with the intent to achieve an individualized target force. In order to manipulate available WM resources, every ten strikes, participants were asked to recall and then retain a sequence of 5 digits (high load group: n = 21) or 2 digits (low load group: n = 21). The task constraints favored the functionality (or appropriateness) of a qualitatively distinct, non-obvious solution. Functionality was assessed using the force registered for each strike. Originality was assessed in terms of how infrequently actions occurred. Finally, search behavior was quantified based on changes in which limb was used and changes in which part of the limb was used from one strike to the next. There were no significant effects of WM load on creativity outcomes, solution search, or task success. Rather, task success was related to efficient search and creativity. Future research should focus on constraints (other than WM resources) that promote efficient search.     

Some Facts from the Biography of A. R. Luria

The biographical sketches from Luria's life reveal the capricious political changes and their effect on the development of Soviet neuropsychology. The picture that emerges is of an individual who survived several ideological reprisals. He introduced Vygotsky into the mainstream of psychology, and continued to advance the study of cognitive functions within the context of neuroanatomy of the brain. And yet, he had an open mind judged by his interest in Freud, and welcoming to his clinic pioneers of psychology such as Piaget, Bruner and Pribram. Also included are intimate impressions of a daughter of her father, who like his young mentor, Vygotsky was a near-genius. He was unvanquished by adversities, doggedly working away to extend the frontiers of the science of human mind.     

Amygdala activation during masked presentation of emotional faces predicts conscious detection of threat-related faces

It has been argued that critical functions of the human amygdala are to modulate the moment-to-moment vigilance level and to enhance the processing and the consolidation of memories of emotionally arousing material. In this functional magnetic resonance study, pictures of human faces bearing fearful, angry, and happy expressions were presented to nine healthy volunteers using a backward masking procedure based on neutral facial expression. Activation of the left and right amygdala in response to the masked fearful faces (compared to neutral faces) was significantly correlated with the number of fearful faces detected. In addition, right but not left amygdala activation in response to the masked angry faces was significantly related to the number of angry faces detected. The present findings underscore the role of the amygdala in the detection and consolidation of memory for marginally perceptible threatening facial expression.     

Being a self: considerations from functional imaging

Having a self is associated with important advantages for an organism.These advantages have been suggested to include mechanisms supporting elaborate capacities for planning, decision-making, and behavioral control. Acknowledging such functionality offers possibilities for obtaining traction on investigation of neural correlates of self-hood. A method that has potential for investigating some of the brain-based properties of self arising in behavioral contexts varying in requirements for such behavioral guidance and control is functional brain imaging. Data obtained with this method are beginning to converge on a set of brain areas that appear to play a significant role in permitting conscious access to representational content having reference to self as an embodied and independent experiencer and agent. These areas have been identified in a variety of imaging contexts ranging from passive state conditions in which they appear to manifest ongoing activity associated with spontaneous and typically 'self-related' cognition, to tasks targeting explicitly experienced properties of self, to demanding task conditions where activity within them is attenuated in apparent redirection of cognitive resources in the service of task guidance and control. In this paper, these data will be reviewed and a hypothesis presented regarding a significant role for these areas in enabling degrees of self-awareness and participating in the management of such behavioral control.     

Critical appraisal of the discussion on delay discounting by Bailey et al. and Stein et al.: A scientific proposal for a reinforcer pathology theory 3.0

Delay discounting is one of the most studied phenomena in Psychology in the last decades. Recently, it has been proposed as a transdiagnostic variable accounting for several psychopathological problems. A review of current practices and clinical application (Bailey et al., 2021) and a response article (Stein et al., 2022) have been recently published. Despite both of them being stimulating, the articles raise issues needing further discussion. The first part of the present article critically appraises both publications by highlighting their strengths/limitations and offers an alternate perspective that clarifies some theoretical issues and allows new lines in research. In the second part, one of these new lines of research is presented by describing a research proposal based on the analysed critiques and current developments in both psychopathology and addiction research. This article contributes to the discussion on delay discounting suggesting alternative interpretations and future studies to improve theoretical models.     

Effects of tasks on BOLD signal responses to sentence contrasts: Review and commentary

Functional neuroimaging studies of syntactic processing have been interpreted as identifying the neural locations of parsing and interpretive operations. However, current behavioral studies of sentence processing indicate that many operations occur simultaneously with parsing and interpretation. In this review, we point to issues that arise in discriminating the effects of these concurrent processes from those of the parser/interpreter in neural measures and to approaches that may help resolve them.     

Neurofunctional (re)organization underlying narrative discourse processing in aging: evidence from fNIRS

Relatively few studies have analyzed the mechanisms underlying the cognitive changes that affect language in the elderly, and fewer have done so for narrative discourse. The goal of this study was to explore the neurofunctional changes associated with aging for different components of narrative discourse. Functional near-infrared spectroscopy (fNIRS) and behavioral data on 10 younger adults and 10 healthy elderly participants were collected. Ten younger adults in a non-proficient second language condition were included to explore the possibility that the age-related neurofunctional reorganization partly expresses demanding resource allocation. Results show within- and across-hemispheric differences in the neurofunctional pattern of activation in the older participants with reference to the younger ones, partially shared with the low-proficiency young adults, providing support for the recognized mechanisms underlying neural reserve and compensation. fNIRS was shown to be appropriate for studying the age-related neurofunctional reorganization of complex cognitive abilities.     

Effects of product type and contextual cues on eliciting naive theories of popularity and exclusivity

This research shows in a series of studies that exposing consumers to functional products evokes the naive theory of popularity, whereas exposing them to self-expressive products induces belief in the naive theory of exclusivity. The research further demonstrates that when the naive theory elicited by product type is matched by the appropriate contextual purchasing cues regarding the interest of others, it results in greater purchase intentions than when those cues are mismatched. The research specifies that the matching effect for functional products is mediated by consumers' perceptions of product quality, whereas mediation for self-expressive products occurs through consumers' self-perceptions regarding the extent to which the product conveys uniqueness. Finally, the research illustrates that an explicit signal of product quality (e.g., a favorable rating in Consumer Reports) attenuates the effect associated with the contextual cues regarding the interest of others.     

Effects of motor intention on the perception of somatosensory events: A behavioural and functional magnetic resonance imaging study

The intention to execute a movement can modulate our perception of sensory events, and this modulation is observed ahead of both ocular and upper limb movements. However, theoretical accounts of these effects, and also the empirical data, are often contradictory. Accounts of “active touch”, and the premotor theory of attention, have emphasized how movement intention leads to enhanced perceptual processing at the target of a movement, or on the to-be-moved effector. By contrast, recent theories of motor control emphasize how internal “forward” model (FM) estimates may be used to cancel or attenuate sensory signals that arise as a result of self-generated movements. We used behavioural and functional brain imaging (functional magnetic resonance imaging, fMRI) to investigate how perception of a somatosensory stimulus differed according to whether it was delivered to a hand that was about to execute a reaching movement or the alternative, nonmoving, hand. The results of our study demonstrate that a somatosensory stimulus delivered to a hand that is being prepared for movement is perceived to have occurred later than when that same stimulus is delivered to a nonmoving hand. This result indicates that it takes longer for a tactile stimulus to be detected when it is delivered to a moving limb and may correspond to a change in perceptual threshold. Our behavioural results are paralleled by the results of our fMRI study that demonstrated that there were significantly reduced blood-oxygen-level-dependent (BOLD) responses within the parietal operculum and insula following somatosensory stimulation of the hand being prepared for movement, compared to when an identical stimulus was delivered to a nonmoving hand. These findings are consistent with the prediction of FM accounts of motor control that postulate that central sensory suppression of somatosensation accompanies self-generated limb movements, and with previous reports indicating that effects of sensory suppression are observed in higher order somatosensory regions.