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101.
由于境外药品审批的滞后性及患者经济负担等原因,代购未经批准进口的境外原研药及仿制药现象在我国客观存在,一旦进入公诉机关视野成为备受瞩目的“药神案”,往往要在市场秩序与患者生命健康权之间相平衡。新修订的《药品管理法》回归药品实效性,将“未经批准进口的药品”排除在“假药”范畴外,使得此类行为不再构成销售假药罪,但这并不意味着进口、销售未经批准的药品完全合法化,其仍可构成行政违法,甚至刑事犯罪。在总结裁判文书网公布的相关案例基础上,通过实证分析进一步探究此类案件的法律适用,以期实现司法裁判的统一。 相似文献
102.
抗抑郁药应用选择的思考 总被引:1,自引:1,他引:1
目前市场上可供选择的抗抑郁药越来越多.从系统方法论、医学模式转变和矛盾重点论的角度来阐述临床上应该如何选择用药,才能使治疗效果和医疗费用更符合个体的情况,达到比较和谐的状态. 相似文献
103.
Hamid Mavani 《The Journal of religious ethics》2014,42(2):263-284
The legal‐ethical dynamism in Islamic law which allows it to respond to the challenges of modernity is said to reside in the institution of ijtihād (independent legal thinking and hermeneutics). However, jurists like Mohsen Kadivar and Ayatollah Fa?lalla have argued that the “traditional ijtihād” paradigm has reached its limits of flexibility as it allows for only minor adaptations and lacks a rigorous methodology because of its reliance on vague and highly subjective juridical devices such as public welfare (ma?la?a), imperative necessity (?arūra), emergency (i?tirār), need (?āja), averting difficulty (‘usr) and distress (?araj), hardship (mashaqqa), and harm (?arar) without interrogating the fundamentals (u?ūl) of ijtihād. In contrast, in the “foundational ijtihād” model theology, ethics, intellect, epistemology, linguistics, hermeneutics, modern sciences, history, cosmology, anthropology, and the sources of Islamic legal theory (u?ūl al‐fiqh) interact with one another to obtain resolutions that are just and non‐discriminatory. 相似文献
104.
Daniel Buda 《International review of missions》2019,108(1):100-111
This article begins with a few thoughts and some historical and canonical encounters about how lay and ordained people with disabilities have been involved in Orthodox mission work in the past. It then presents two concrete contemporary situations in which people with disabilities are involved in Orthodox ordained ministry work despite the persisting tradition that disabled people not be ordained. The first example is taken from the Eritrean Orthodox Tewahedo Church, where the involvement of people with disabilities in both ordained and lay ministry provides significant support for a church that lives in a delicate situation. The second example is taken from the Romanian Orthodox Church and presents the case of Father Theophilus P?r?ian, one of the most prominent contemporary Romanian Orthodox monastic figures, who served as an ordained priest despite his disability. This article pleads for a deeper involvement of disabled people in both ordained and lay ministry in Orthodox churches. 相似文献
105.
Brenda E. Groen Viola C. Altmann Ruud W. Verhagen Yves C. Vanlandewijck Noël L.W. Keijsers 《Journal of motor behavior》2019,51(1):43-48
Trunk coordination is essential for many activities of daily living in wheelchair users. This study investigated whether Fitts' law is applicable to trunk movements in a sitting position. Fourteen healthy adults performed two series of 24 tasks of trunk flexion–extension movements in a sitting position. The results showed significant linear relationships between average group movement time (MT) and index of difficulty (ID) over all tasks (r2 = 0.92) and within target distances (0.94 < r2 < 1.00). Target distance affected intercept and slope (P < 0.001). Hence, Fitts' law is applicable to the studied trunk movements in a sitting position, indicating these trunk movements tasks could serve as a basis for qualitative trunk coordination tests. Transferability of these conclusions to wheelchair users, and optimal test design should be further investigated. 相似文献
106.
We investigated the effects of gender-based social categories (i.e., men, women, boys, and girls) on attitudes about child sexual abuse and individual differences in the use of such categories. In four experiments, we systematically varied perpetrators’ sex and victims’ sex. In three investigations, we assessed personality variables potentially related to participants’ use of these social categories. Across these four experiments, we varied perpetrator-victim relationships (teacher-student, neighbors) and victims’ ages. In experiment one, individuals had the least negative attitude about child sexual abuse involving adult female neighbors and eighth grade male neighbors. In experiment two, we replicated this effect with fifth grade victims and demonstrated that attitudes were moderated by individual differences in intolerance of ambiguity. In experiment three, we again replicated the aforementioned effect while (a) extending this finding to teacher-student relationships with eighth grade adolescent victims and (b) demonstrating the need for cognition was a moderator. In experiment four, we again replicated (a) our perpetrator sex/victim sex interactive effect and (b) need for cognition moderation while also demonstrating that these effects were applicable to fifth grade victims. Methodological limitations as well as clinical and policy implications (e.g., attenuating the underreporting incidents of child sexual abuse) are discussed. 相似文献
107.
A substantial body of research has examined the speed-accuracy tradeoff captured by Fitts’ law, demonstrating increases in movement time that occur as aiming tasks are made more difficult by decreasing target width and/or increasing the distance between targets. Yet, serial aiming movements guided by internal spatial representations, rather than by visual views of targets have not been examined in this manner, and the value of confirmatory feedback via different sensory modalities within this paradigm is unknown. Here we examined goal-directed serial aiming movements (tapping back and forth between two targets), wherein targets were visually unavailable during the task. However, confirmatory feedback (auditory, haptic, visual, and bimodal combinations of each) was delivered upon each target acquisition, in a counterbalanced, within-subjects design. Each participant performed the aiming task with their pointer finger, represented within an immersive virtual environment as a 1 cm white sphere, while wearing a head-mounted display. Despite visual target occlusion, movement times increased in accordance with Fitts’ law. Though Fitts’ law captured performance for each of the sensory feedback conditions, the slopes differed. The effect of increasing difficulty on movement times was least influential in the haptic condition, suggesting more efficient processing of confirmatory haptic feedback during aiming movements guided by internal spatial representations. 相似文献
108.
Anticipatory postural adjustments (APAs) are an integral part of standing balance. Previous research with balance control has shown that adopting an external focus of attention, compared to an internal focus of attention, yields better performance during motor skills. Despite the importance of APAs, especially among older adults, and the potential benefits of adopting an external focus of attention, studies investigating methods for improving APAs are limited. The aim of this study was to compare behavioral, kinematic and APAs measures while adopting different foci of attention among young and older adults when performing a lower extremity Fitts’ task. Ten young adults (mean age 24 years ± 4.37) and ten older adults (mean age 75 years ± 5.85) performed a lower-extremity reaching task (Fitts’ task) while adopting an external focus (focus on target) and an internal focus (focus on limb) in a within-subject design. A motion capture system was used to record participants’ movement data. Custom software derived movement time (MT), peak velocity (PV), time to peak velocity (ttPV) and variability at target (SDT). Electromyography (EMG) was used to determine APAs onset and magnitude. The findings showed that an external focus of attention led to significantly shorter MT, higher PV, shorter ttPV and more accuracy when reaching the target (SDT) for both age groups. Also, EMG results showed that, with an external focus, APAs onset occurred earlier and APAs magnitude was more efficient. As predicted by Fitts’ Law, participants spent more time executing movements to targets with higher indices of difficulty. Older adults compared to young adults were more adversely affected by the increase of difficulty of the Fitts’ task, specifically, on measures of APAs. In conclusion, adopting an external focus of attention led to better overall movement performance when performing a lower extremity Fitts’ task. The task used in the present study can distinguish between APAs for older and young adults. We recommend that future studies expand on our findings in order to establish a performance-based objective measure of APAs to assess clinical interventions for postural control impairment. 相似文献
109.
Christel Mollard 《Médecine & Droit》2017,2017(142):1-10
Medically assisted procreation includes techniques that may allow infertile couples to procreate. However, the application of 2011 bioethics law reveals lots of paradox and high-risk behaviors which arouse the question of the relevance and advisable aspect of its opening to all women. 相似文献
110.
Edwige Rude-Antoine 《Médecine & Droit》2017,2017(142):15-23
The announcement of the cancer diagnosis and his treatment is an important moment in the set up of the doctor–patient relationship. The law of contracts has long governed the relationship between the doctor and the patient. But the legislature clearly demonstrated its will to consider the patient as full actor of his health, leaving the regime of medical decision, the shared decision. This shared decision is based on an obligation to inform the patient on his health and knows many exceptions (minor patients or adults under guardianship, emergency). In Oncology, the medical decision is a decision coordinated between doctors in the multidisciplinary consultation meetings. This decision is considered as a guarantee of the quality of the medical care. It does not preclude the time of the doctor–patient relationship. 相似文献