进化论与医学教学

达尔文主义在生物学中是一个很重要的理论,它对医学事实所做的进化论解释同样是不应忽视的。但是由于偶然的原因,它一直不能走上医学院的讲台。尽管要克服许多困难,我们还是应该把一些最重要的进化理论传授给我们的医学生,因为这对于他们未来行医是大有益处的。     

抗生素过度使用的成因与对策

抗生素过度使用是一个全球性的医学、社会和公共卫生问题,成因复杂,包括医学本身的局限、缺欠,医生的水平和素质,患者和公众的态度,医疗机构和社会的问题等,从根本上解决这个问题,是一项涉及全社会的、从医学、法律、等诸多方面共同协作努力的系统工程,任重而道远。     

“I'm Having a Little Struggle With This,Can You Help Me Out?”: Examining Impacts and Processes of a Social Capital Intervention for First‐Generation College Students

Social capital plays a key role in college and career success, and research indicates that a dearth of on‐campus connections contributes to challenges first‐generation college students face in effectively navigating the college environment. This study investigates a novel intervention that focuses on the development of skills and attitudes to empower first‐generation college students to cultivate social capital and on‐campus connections during the transition to college. A mixed methods, explanatory design was used to evaluate impacts and processes of the intervention among first‐generation college students (n = 164) in the context of an ethnically diverse, urban, public university in the Northeast. Results indicated that students who participated in the intervention demonstrated improved attitudes and behaviors around seeking support in college, closer relationships with instructors, and higher GPAs at the end of their first year in college. These results suggest the potential benefits of a relatively scalable approach to supporting the needs of first‐generation college students.     

The acquisition of allophonic rules: statistical learning with linguistic constraints

Phonological rules relate surface phonetic word forms to abstract underlying forms that are stored in the lexicon. Infants must thus acquire these rules in order to infer the abstract representation of words. We implement a statistical learning algorithm for the acquisition of one type of rule, namely allophony, which introduces context-sensitive phonetic variants of phonemes. This algorithm is based on the observation that different realizations of a single phoneme typically do not appear in the same contexts (ideally, they have complementary distributions). In particular, it measures the discrepancies in context probabilities for each pair of phonetic segments. In Experiment 1, we test the algorithm's performances on a pseudo-language and show that it is robust to statistical noise due to sampling and coding errors, and to non-systematic rule application. In Experiment 2, we show that a natural corpus of semiphonetically transcribed child-directed speech in French presents a very large number of near-complementary distributions that do not correspond to existing allophonic rules. These spurious allophonic rules can be eliminated by a linguistically motivated filtering mechanism based on a phonetic representation of segments. We discuss the role of a priori linguistic knowledge in the statistical learning of phonology.     

The sensory‐cognition association in adulthood: Different magnitudes for processing speed,inhibition, episodic memory,and false memory?

One hundred and forty-six participants (age range = 20-80) completed a battery of tests designed to measure visual acuity, processing speed, inhibition, episodic memory and false memory. The relations between visual acuity and general cognitive ability, as well as between visual acuity and the indicators of this construct, were evaluated with structural equation modeling. The measurement model confirmed that the indicators of the individual cognitive abilities could be grouped into a general cognitive functioning factor. However, the relation between episodic and false memory was not completely explained by the shared association with this general factor. Furthermore, visual acuity predicted approximately half of the age-related variance in the general cognition factor. Also, the proportion of age-related variance shared with vision was highest in inhibition and lowest in false memory. The results are discussed in the light of common cause accounts of cognitive aging.     

Maternal mind-mindedness over infants’ first three months

Maternal mind-mindedness refers to mothers’ ability to reflect upon their infants’ mental states and respond appropriately. The present study assessed mind-mindedness longitudinally from the newborn period to the infant age of three months. The study is the first to assess maternal mind-mindedness in the infant’s early life prior to three months (one week, one month, two months, three months). To measure maternal mind-mindedness, mothers’ speech to their infants is coded for mental state comments about the infants’ thoughts, desires, and emotions. Appropriate mind-minded comments are judged to accurately reflect the infants’ mental states; non-attuned mind-minded comments are judged to misinterpret the infants’ mental states. Mothers’ individual stability (rank order stability) and group level continuity (mean level of stability across the infant ages) were assessed. Mothers showed modest temporal stability in both appropriate and non-attuned mind-mindedness over the infants’ first three months. The continuity of mind-mindedness showed that appropriate mind-mindedness increased over the infant ages, but non-attuned mind-mindedness showed no change. In infants’ early lives, mothers’ ability to accurately interpret their infants’ mental states is enhanced as the mother-infant relationship develops and infants become more communicative partners.     

Academic achievement in first-year Portuguese college students: the role of academic preparation and learning strategies

This paper analyses the role of academic preparation and learning strategies in the prediction of first-year Portuguese college students' academic achievement, considering students' sex and academic field attended. A sample of 445 first-year college students (68.5% female) from the University of Minho (25.8% enrolled in economics, 35.3% in science/technology, and 38.9% in humanities degrees) participated in the study. Students answered a questionnaire on learning strategies in the classroom at the end of the first semester, which consisted of 44 items organized in five dimensions: comprehensive approach, surface approach, personal competency perceptions, intrinsic motivation, and organization of study activities. Academic achievement (grade point average at the end of first year) and academic preparation (students' higher education access mark) were obtained through the academic records of the university. Results showed that academic preparation was the strongest predictor of first-year academic achievement, and only marginal additional variance was explained by learning strategies as assessed by the self-reported questionnaire. There were sex and academic field differences, but these variables do not seem strong enough to affect the results, although the different percentages of variance captured by each model and the different weights associated to higher education access mark, stimulate the use of these and/or other personal and contextual variables when analysing the phenomenon.     

Cognitive control of language production in bilinguals involves a partly independent process within the domain-general cognitive control network: evidence from task-switching and electrical brain activity

In highly proficient, early bilinguals, behavioural studies of the cost of switching language or task suggest qualitative differences between language control and domain-general cognitive control. By contrast, several neuroimaging studies have shown an overlap of the brain areas involved in language control and domain-general cognitive control. The current study measured both behavioural responses and event-related potentials (ERPs) from bilinguals who performed picture naming in single- or mixed-language contexts, as well as an alphanumeric categorisation task in single- or mixed-task context. Analysis of switch costs during the mixed-context conditions showed qualitative differences between language control and domain-general cognitive control. A 2 × 2 ANOVA of the ERPs, with domain (linguistic, alphanumeric) and context (single, mixed) as within-participant factors, revealed a significant interaction, which also suggests a partly independent language-control mechanism. Source estimations revealed the neural basis of this mechanism to be in bilateral frontal-temporal areas.     

Children Apply Principles of Physical Ownership to Ideas

Adults apply ownership not only to objects but also to ideas. But do people come to apply principles of ownership to ideas because of being taught about intellectual property and copyrights? Here, we investigate whether children apply rules from physical property ownership to ideas. Studies 1a and 1b show that children (6–8 years old) determine ownership of both objects and ideas based on who first establishes possession of the object or idea. Study 2 shows that children use another principle of object ownership, control of permission—an ability to restrict others’ access to the entity in question—to determine idea ownership. In Study 3 , we replicate these findings with different idea types. In Study 4 , we determine that children will not apply ownership to every entity, demonstrating that they do not apply ownership to a common word. Taken together, these results suggest that, like adults, children as young as 6 years old apply rules from ownership not only to objects but to ideas as well.