An Investigation of Genetic Counselors' Discussions of Genetic Discrimination with Cancer Risk Patients

Twenty-five genetic counselors who see familial cancer risk patients were interviewed about their definitions of genetic discrimination, perceptions of patient risk for discrimination, frequency and type of discrimination experienced by their patients, sources of information about discrimination, and what they tell patients about genetic discrimination. There was variability in participant definitions and content of discussions of genetic discrimination. Although 82% regarded risk to be low to theoretical, 40% reported possible instances of genetic discrimination, including insurance companies requiring results to cover procedures, denial of life/health insurance, social discrimination, and employment discrimination. Ninety-six percent of the sample reported always or almost always discussing genetic discrimination, and one or more of the following: insurance discrimination risks, protective legislation, no known cases positively documenting discrimination, strategies to avoid discrimination, and uncertainty of protective measures. The majority use current literature and research as information sources. Practice, policy, and research implications are discussed.     

Speech perception in rats: use of duration and rise time cues in labeling of affricate/fricative sounds

The voiceless affricate/fricative contrast has played an important role in developing auditory theories of speech perception. This type of theory draws some of its support from experimental data on animals. However, nothing is known about differential responding of affricate/fricative continua by animals. In the current study, the ability of hooded rats to "label" an affricate/fricative continuum was tested. Transfer (without retraining) to analogous nonspeech continua was also tested. The nonspeech continua were chosen so that if transfer occurred, it would indicate whether the animals had learned to use rise time or duration cues to differentiate affricates from fricatives. The data from 9 of 10 rats indicated that rats can discriminate between these cues and do so in a similar manner to human subjects. The data from 9 of 10 rats also demonstrated that the rise time of the stimulus was the basis of the discrimination; the remaining rat appeared to use duration.     

Salamanders (<Emphasis Type="Italic">Plethodon cinereus</Emphasis>) go for more: rudiments of number in an amphibian

Techniques traditionally used in developmental research with infants have been widely used with nonhuman primates in the investigation of comparative cognitive abilities. Recently, researchers have shown that human infants and monkeys select the larger of two numerosities in a spontaneous forced-choice discrimination task. Here we adopt the same method to assess in a series of experiments spontaneous choice of the larger of two numerosities in a species of amphibian, red-backed salamanders (Plethodon cinereus). The findings indicate that salamanders "go for more," just like human babies and monkeys. This rudimentary capacity is a type of numerical discrimination that is spontaneously present in this amphibian. Electronic Publication     

Nicotine vs. ethanol discrimination: Extinction and spontaneous recovery of responding

Studies regarding extinction and spontaneous recovery of the discriminative stimulus effects of drugs are limited. Eight rats were initially trained to discriminate nicotine (0.4 mg/kg) vs. ethanol (800 mg/kg). For four rats, itraperitaneal (IP) administrations of nicotine fifteen minutes prior to fifteen-minute training sessions served as a discriminative stimulus (S^D) for predicting food-reinforced lever pressing (VI-1 min). On other sessions ethanol functioned in predicting nonreinforcement (S^Δ). The stimulus roles of the drugs were counterbalanced for the remaining four rats. S^Δ and S^D sessions alternated quasi-randomly with two daily sessions at 1000 and 1400 hours. Discriminative control was not disrupted following ten extinction sessions under a non-drug/saline condition, but was disrupted following extinction sessions under the original training drugs. Instances of spontaneous recovery (SR) occurred throughout extinction under the drug condtions. There was no evidence for SR two weeks following extinction, but partial recovery four weeks following the final extinction phase. Contextual status (context renewal) had neither a restorative or disruptive impact on extiguished or discriminated responding, respectively. Theser results support and extend the limited number of other studies by demonstrating extinction and spontaneous recovery of responding discriminated bytwo distinct drugs. Some theoretical interpretations regarding history effects and training in the context of drug discrimination are entertained.     

Effects of interval duration on temporal processing in schizophrenia

INTRODUCTION: Temporal processing has received scant attention in the literature pertaining to cognitive deficits in patients with schizophrenia. Previous research suggests that patients with schizophrenia exhibit temporal perception deficits on both auditory and visual stimuli. The current study investigated the effects of interval manipulation to (1) replicate the original findings with a larger sample and an increased number of trials (2) assess the degree to which both patients and controls can differentiate temporal changes in a range of experimental interstimulus intervals, and (3) explore whether different interstimulus interval durations pose different levels of difficulty for the patients with schizophrenia. METHODS: Participants were asked to decide whether temporal intervals were shorter or longer than standard intervals on a computer-based auditory temporal perception task. The standard interval remained the same duration throughout the various tasks. The interstimulus interval separating the standard and experimental intervals varied in the range of 500, 1000, or 3000 ms. Data are presented for a sample of 16 patients with schizophrenia and 15 controls. RESULTS: Data suggest that patients with schizophrenia exhibit deficits in differentiating interval durations across all paradigms compared to their control-group peers on a range of auditory tasks (p<.001). CONCLUSIONS: These results are consistent with a general temporal deficit in schizophrenia. However, the roles of medication and localization are also addressed.     

The effects of morphine on fixed-interval patterning and temporal discrimination

Changes produced by drugs in response patterns under fixed-interval schedules of reinforcement have been interpreted to result from changes in temporal discrimination. To examine this possibility, this experiment determined the effects of morphine on the response patterning of 4 pigeons during a fixed-interval 1-min schedule of food delivery with interpolated temporal discrimination trials. Twenty of the 50 total intervals were interrupted by choice trials. Pecks to one key color produced food if the interval was interrupted after a short time (after 2 or 4.64 s). Pecks to another key color produced food if the interval was interrupted after a long time (after 24.99 or 58 s). Morphine (1.0 to 10.0 mg/kg) decreased the index of curvature (a measure of response patterning) during fixed intervals and accuracy during temporal discrimination trials. Accuracy was equally disrupted following short and long sample durations. Although morphine disrupted temporal discrimination in the context of a fixed-interval schedule, these effects are inconsistent with interpretations of the disruption of response patterning as a selective overestimation of elapsed time. The effects of morphine may be related to the effects of more conventional external stimuli on response patterning.     

The Connection between Perceived Workplace Discrimination and Viewing Work as a Spiritual Calling

Research shows that perceived workplace discrimination shapes an individual's job satisfaction and intent to leave a job. This study considers whether these impacts may be attenuated if an individual views their work as a spiritual calling. Using data from a nationally representative survey (N = 9,907), our analysis shows that perceived work discrimination due to race, gender, and religion are all independently associated with less job satisfaction net of a variety of other measures. Viewing work as a spiritual calling is associated with greater job satisfaction, even when accounting for traditional measures of religiosity. The negative impact of perceived discrimination on job satisfaction is weaker among those who view work as a spiritual calling. These findings provide evidence of the mechanisms underlying job satisfaction and have implications for understanding how religion might help mitigate the negative consequences of perceived discrimination in the workplace, or allow discrimination to potentially go unaddressed.     

Higher attention bias for fear at 8 months of age is associated with better socioemotional competencies during toddlerhood

BackgroundIn previous studies, an attention bias for signals of fear and threat has been related to socioemotional problems, such as anxiety symptoms, and socioemotional competencies, such as altruistic behaviors in children, adolescents and adults. However, previous studies lack evidence about these relations among infants and toddlers.AimsOur aim was to study the association between the individual variance in attention bias for faces and, specifically, fearful faces during infancy and socioemotional problems and competencies during toddlerhood.Study design and subjectsThe study sample was comprised of 245 children (112 girls). We explored attentional face and fear biases at the age of 8 months using eye tracking and the face-distractor paradigm with neutral, happy and fearful faces and a scrambled-face control stimulus. Socioemotional problems and competencies were reported by parents with the Brief Infant and Toddler Social Emotional Assessment (BITSEA) when children were 24 months old.Outcome measures and resultsA higher attentional fear bias at 8 months of age was related to higher levels of socioemotional competence at 24 months of age (β = .18, p = .008), when infants’ sex and temperamental affectivity, maternal age, education and depressive symptoms were controlled. We found no significant association between attentional face or fear bias and socioemotional problems.ConclusionsWe found that the heightened attention bias for fearful faces was related to positive outcomes in early socioemotional development. Longitudinal study designs are needed to explore the changes in the relation between the attention bias for fear or threat and socioemotional development during early childhood.     

Moderators of sex- and race-based subgroup differences in assessment center ratings: A meta-analysis

This meta-analysis tested a series of moderators of sex- and race-based subgroup differences using assessment center (AC) field data. We found that sex-based subgroup differences favoring female assessees were smaller among studies that reported: combining AC scores with other tests to compute overall assessment ratings, lower mean correlations between rating dimensions, using more than one assessor to rate assessees in exercises, and providing assessor training. In contrast, we found larger sex-based subgroup differences favoring female assessees among studies that reported: lower proportions of females in assessee pools, conducting a job analysis to design the AC, and using multiple observations of AC dimensions across exercises. We also observed a polynomial effect showing that subgroup differences most strongly favored female assessees in jobs with the highest and lowest rates of female incumbents. We found race-based subgroup differences favoring White assessees were smaller on less cognitively loaded rating dimensions and for jobs with lower rates of Black incumbents. Studies reporting greater overall methodological rigor also showed smaller subgroup differences favoring White assessees. Regarding specific rigor features, studies reporting use of highly qualified assessors and integrating dimension ratings from separate exercises into overall dimension scores showed significantly lower differences favoring White assessees.     

Effects consistent with behavioral contrast during a multiple schedule for discrimination training on mands for attention

This study used a multiple schedule to assess the effects of an S+ or S- in the absence of rules on excessive mand rates with three school-aged children with disabilities and assessed possible contrast effects occurring in conjunction with the intervention. Each of the three participants was exposed to the presence or absence of an S- (black baseball cap). When it was worn, mand approach rates decreased for all three participants; conversely, mand rates increased to twice the baseline rates when the experimenter was not wearing the black baseball cap. Generalization probes conducted for one of the three caregivers showed similar changes when the caregiver wore the cap. Results suggest that effects consistent with positive behavioral contrast occurred with all participants.