Dissociations of language function in dementia: A case study

In this report we describe and attempt to characterize the deterioration in semantic knowledge occurring in a victim of a progressive dementing disease. The subject was unable to match even highly familiar naming words with their actual or pictured referents; instead, she consistently overextended verbal labels to closely associated distractors. The alteration in scope of referential meanings suggested by this overextension effect was apparently related to a breakdown in the structure of underlying categories. On a nonverbal match-to-sample procedure, for example, dogs were treated as exemplars of the cat family. Evidence for the breakdown of semantic knowledge was not limited to picture labeling paradigms. Thus, we found that the subject was unable to utilize semantic context in the written disambiguation of spoken homophones but could, at the same time, use even minimal syntactic cues as the basis for proper lexical selection. This last result was consistent with other lines of evidence pointing to the relative preservation of syntactic operations, in marked contrast to the semantic loss. The importance of this dissociation of function in organic pathology is considered from a number of perspectives, including its relevance to models of language organization in the brain.     

Computer tomographic localization, lesion size, and prognosis in aphasia and nonverbal impairment.

Computerized tomography scans (80) were used to localize infarcts in 70 patients. Twenty-three aphasics were scanned within 35 days from onset, 39 beyond a year, and 18 were nondominant cases. Aphasics were also grouped according to test scores obtained within 35 days of scan. Chronic global aphasics have larger lesions than persisting Broca's aphasics. The area of persisting Broca's aphasia is similarly anterior but larger than that of recovered motor aphasia. Anomic aphasics evolve from Broca's and Wernicke's types with differing localization. Lesion size correlated with severity and recovery, and comprehension among the subtests.     

Cerebral dominance assessed by object- and color-naming latencies: sex and familial sinistrality effects.

Two vocal RT experiments were conducted. The first required the naming of five lateralized drawings of common objects; the second of five hues of equal brightness and saturation. Tachistoscopic exposure time was 100 msec. Both tasks yielded faster RT to stimuli channeled directly to the left hemisphere, demonstrating that the left hemisphere superiority for naming letters or digits obtained in previous tachistoscopic studies was not dependent on the use of alphanumeric stimuli. Interesting sex differences in object-naming and familial sinistrality differences in color-naming were obtained. Compared with other behavioral tasks for assessing language laterality, color-naming seems highly recommended in terms of freedom from spatial-confounding, good percentage agreement with clinical estimates of the frequency of left hemisphere language dominance in right handers, and sensitivity to familial sinistrality influences.     

Lateral-frontal slow potential shifts preceding language acts in deaf and hearing adults

Slow potential EEG shifts (SPSs) recorded over Broca's area and the paired contralateral site preceding cued language acts have been reported to identify the language-dominant hemisphere. A contingent negative variation paradigm SPS method was applied to the comparative study of 10 hearing adults and of 10 adult prelingually deaf persons whose first learned language was American Sign Language. Volunteers performed both language and non-language acts in both oral and manual expressive modes. The hearing group showed no lateralized SPS, failing to replicate previous reports. The deaf group showed a nonsignificant trend opposite in laterality to that of hearing groups in previous reports.     

Stimulus control in a simple instrumental task: The role of internal and external stimuli

Two experiments using rats in a straight alley runway task tested the hypothesis that standard stimuli such as tones and lights (“external” stimuli) and schedule-generated aftereffect stimuli (“internal” stimuli) operate similarly and are similarly subject to the compounding rules specified by R. A. Rescorla and A. R. Wagner (In A. Black & W. Prokasy (Eds.), Classical conditioning II: Current theory and research. New York: Appleton-Century-Crofts, 1972). The experimental task was an instrumental analog of the classic blocking experiment (L. J. Kamin, In M. R. Jones (Ed.). In Experiment 1, blocking of an external discriminative stimulus by a different asymptotic discrimination was accomplished. In Experiment 2, blocking of an internal stimulus discrimination by an asymptotic external stimulus discrimination was obtained. The present results support the view that internal and external stimuli are indeed similar and function in the same manner with regard to blocking of stimulus control.     

Part of speech and phonological form implied in written-word comprehension: Evidence from homograph disambiguation by normal and aphasic subjects

A sentence construction experiment examining the effect of part of speech and phonological form in written-word comprehension is reported. Normal and aphasic subjects had to write sentences incorporating a given word pair, one word was a homograph (e.g., “bank”) whose meaning was context-biased by the other (e.g., “money”/“river”). The effect of three psycholinguistic factors on subjects' performance was questioned: (i) The relative frequency of one meaning of the homograph as compared to the other meaning; (ii) The lexical/syntactic ambiguity (“ball”/“can”); (iii) The same/different phonological forms of the two meanings (“fair”/“bass”). The results are discussed in the framework of a model in which multiple special-purpose procedures are involved in normal processing, some of them being differentially impaired by brain disease in Broca's and Wernicke's aphasics.     

Simultaneous and successive syntheses and intelligence

Recent studies on information processing have developed an alternative model of mental abilities which constitutes an integration of Russian clinical research and North American factor analytic research. This model proposes that information may be processed in a simultaneous synthesis or a successive synthesis. The present study examines variations in these syntheses in three intelligence groups in order to identify the types of information processing characteristic of different intelligence groups. A stratified sampling of verbal and nonverbal IQ was used to select 60 boys of age 9–10 in each of three verbal IQ ranges: 71–90, 91–110, and 111–130. A battery of tests used in previous research was administered to all subjects. Multivariate analyses of variance and discriminant analyses indicated that the IQ groups differed markedly on tests used to identify simultaneous synthesis, most notably Raven's Progressive Matrices, and differed slightly less on tests of successive synthesis. Factor analyses of the test intercorrelations for each group revealed more factorial invariance across the IQ groups than had been suggested by a previous exploratory study. It was concluded that strong individual differences exist in simultaneous and successive syntheses over the major portion of the standardized intelligence range, and no high degree of specialization of information processing was characteristic of an intelligence group.     

Book Reviews

Books reviewed:
Michele M. Moody-Adams, Fieldwork in Familiar Places: Morality, Culture, and Philosophy
Hanna Fenichel Pitkin, The Attack of the Blob: Hannah Arendt's Concept of the Social
Susan Haack, Manifesto of a Passionate Moderate     

About Skinner and time: behavior-analytic contributions to research on animal timing

The article discusses two important influences of B. F. Skinner, and later workers in the behavior-analytic tradition, on the study of animal timing. The first influence is methodological, and is traced from the invention of schedules imposing temporal constraints or periodicities on animals in The Behavior of Organisms, through the rate differentiation procedures of Schedules of Reinforcement, to modern temporal psychophysics in animals. The second influence has been the development of accounts of animal timing that have tried to avoid reference to internal processes of a cognitive sort, in particular internal clock mechanisms. Skinner's early discussion of temporal control is first reviewed, and then three recent theories-Killeen & Fetterman's (1988) Behavioral Theory of Timing; Machado's (1997) Learning to Time; and Dragoi, Staddon, Palmer, & Buhusi's (2003) Adaptive Timer Model-are discussed and evaluated.