早期目标血糖管理下严重脓毒症患者HMGB1的变化及其临床意义

探讨早期目标血糖管理对严重脓毒症患者HMGB1变化的影响.严重脓毒症患者随机分为血糖控制A（4.4mmol/L~6.1mmol/L）、B（6.2mmol/L~8.3mmol/L）、C（8.4mmol/L~10.0mmol/L）三组.给予早期目标血糖管理,入ICU后0d、1d、3d、5d、7d采血测TNF-α、HMGB1浓度.三组TNF-α、HMGB1浓度及APACHEⅡ评分均呈下降趋势,A组HMGB1浓度及APACHEⅡ评分在第7d较B、C组明显降低（P＜0.05）.A组28d病死率较B、C组降低（P＆gt;0.05）.严重脓毒症患者在早期目标血糖管理下,显著降低HMGB1浓度,降低病死率和改善预后,HMGB1可用来评价脓毒症的严重程度及预后.     

Sit-to-stand movement in children: A longitudinal study based on kinematics data

Although the ability to stand from a seated posture is relevant for clinical practice, there are few studies investigating the process of acquisition and refinement of the motor components involved in sit-to-stand movement (STS) in children. Therefore, this longitudinal study aims to describe kinematic characteristics of the STS movement in children from 12 to 18 months, and also to investigate the relationship between changes in STS movement and childrens’ daily-life mobility. Ten healthy children were evaluated at 12,13,14,15 and 18 months of age. A motion analysis system was used to measure total duration of STS movement and angular movements of each joint, and frequencies of successful and unsupported STS were obtained. The Pediatric Evaluation of Disability Inventory was used to assess childrens’ daily-life mobility. Results showed that children tend to increase the frequency of successful trials over the months by reducing the total duration and decreasing peak ankle dorsiflexion and trunk flexion during STS. Children also started to stand up from chair with decreased trunk flexion angle among ages. At the end of the STS, we observed decreases in trunk flexion and knee flexion over age. Furthermore, kinematic characteristics that reflect improvements in STS movement are related to better performance of functional skills and decreased level of assistance provided by the caregiver in daily-life mobility of younger children. However, the strength of these associations decreases from 14 months of age onwards.     

无边界职业生涯研究:二十年回顾与展望

当今社会个体职业生涯发展与管理的背景发生了巨大变化,无边界职业生涯应运而生,它指一种不限于单一雇佣范围的一系列就业机会的职业路径。文章在介绍概念及发展历程的基础上,综述了影响无边界职业生涯的四类因素,并指出以往研究在概念、发展现状、维度和影响广度等方面存在的争议。未来应该针对当前争议有目的地展开研究,界定更加清晰的概念,扩展对无边界职业生涯类型的研究,以及这种流动环境在更深层上对个体以及组织的影响。     

Effects of Age on Dual-Task Walking While Listening

This study examined the effects of age on single- and dual-task listening and walking during virtual street crossing. Seventeen younger and 12 older adults participated. In each listening trial, three sentences were presented simultaneously from separate locations. Participants were instructed to report the target sentence. Predictability of the target sentence location was varied. Treadmill walking was measured using motion analysis. Measures included word recognition accuracy, head and trunk angles, and spatiotemporal gait parameters. Older adults exhibited a more upright head alignment and less variability in stride time during dual-tasking, particularly under less certain target sentence location conditions. Younger adults’ walking was unaffected by dual-task demands. Together, the results indicate greater postural prioritization in older adults than young.     

流动性、教育安置方式和心理弹性对流动儿童孤独感的影响:一项追踪研究

采用潜变量增长模型对426名流动儿童进行四次追踪测查,旨在考察流动儿童孤独感的变化趋势,探索不同流动性和教育安置方式的流动儿童孤独感变化的差异性以及心理弹性对孤独感变化的促进性作用。结果发现：（1）流动儿童的孤独感呈线性下降趋势;（2）打工子弟学校流动儿童的孤独感起始水平显著高于公立学校流动儿童;流动性高的儿童的孤独感起始水平高于流动性低的儿童,但流动性和教育安置方式对孤独感的发展趋势没有显著预测作用;（3）对于流动儿童来说,较高的心理弹性水平不仅能显著预测更低的孤独感起始水平,同时也能显著预测更快的孤独感的下降速率。本研究启示,增加进入公立学校学习的机会、降低流动频率和提升心理弹性对降低流动儿童的孤独感水平具有重要的意义。     

Getting emotional about ‘brain mobility’

Our purpose in this paper is to offer an historical and cultural account of the relationships between globalisation, the nation-state, emotion and the academic mobility policies that are driven by the knowledge economy. In so doing we seek to contribute to the emerging literature on the links between emotion, policy and globalisation. These links are under-researched and under-theorised. Seeking to build on Arjun Appadurai’s work on the global cultural economy, we coin the term ‘emoscapes’. Emoscapes, we argue, involve the movement and mobilisation of emotion on intersecting global, national and personal scales. This concept helps us to illuminate how emotion circulates within global power and knowledge geographies. We discuss global policy atmospherics in terms of the structural power relationship between different nation-states and regions, the feelings such relationships generate on matters of ‘brain mobility’ and the implications for policy. This provides a broad context for our discussion of the nation-state itself where we consider how the nation-state’s position within these global power formations contributes to national feelings. Taking the example of Australia, we look at its emotional archive, the implications for the ways in which Australian policies have territorialised the global ‘brain mobility’ policy discourse and the nation-state policy atmospherics involved. Ultimately we show how emoscapes have entered and influenced policy and how they are part of global and national power and knowledge geographies.     

骨质疏松症对腰椎形态及其大体活动范围的影响

了解不同程度骨质疏松患者椎骨、椎间盘形态及腰椎矢状面大体活动度。选取34位在我院查体的老年人,并按骨密度值分组(9正常,11骨量缺少,14骨质疏松症),拍摄腰椎侧位片及磁共振图像,并测量活动度。骨质疏松组与其他两组相比,腰椎椎体前部高度增加,骨质疏松与椎间盘中部膨胀和相应椎体的塌陷有关,而与椎间盘性质无关,其腰椎大体活动范围无明显变化。骨质疏松不仅影响骨矿含量,也影响骨周围软组织,且与椎体终板变化继发椎间盘膨胀相关。     

Women’s occupational career patterns over 27 years: Relations to family of origin, life careers, and wellness

This study aimed at identifying and describing occupational career patterns (OCPs) from age 16 to 43 by applying optimal matching techniques to sequence data obtained from a sample of Swedish women. Women’s occupational trajectories were found to be diverse. Upward mobility (3 patterns) and stable careers (4 patterns) were prevalent, but there were also women characterized by downward mobility, fluctuation and being outside the labor market (1 pattern each). Women’s OCPs were related to family of origin, but more strongly to their overall life career (i.e., multiple role constellations over the life course). The study indicates that occupational mobility patterns do matter in terms of job perceptions, work attitudes, and quality of life. The results generally confirm the popular belief of the advantage of upward mobility, followed by stable occupational careers, whereas women with downward or fluctuating careers fared worst.     

Residential mobility and conditionality of group identification

In three studies, we found that residential mobility accounts for cross-national, regional, and individual differences in the conditionality of identification with a group. In Study 1, participants from a mobile nation (US) showed more conditional identification with other group members than did participants from a stable nation (Japan). In Study 2, we found within-nation, regional variation in this tendency. Specifically, in residentially stable Japanese cities, the attendance to home baseball games was higher when the team was performing well than when it was performing poorly. In contrast, the attendance to the home games was not associated with the team’s performance. Finally, in Study 3 we found individual differences in the conditionality of group identification, such that frequent movers identified with the school more than non-movers did when the school was described favorably, whereas they distanced themselves from the school more than non-movers when their school was described unfavorably. These findings illustrate the role of residential mobility in individual, regional, and cross-national differences in the conditionality of group identification.