Response-dependent point loss and response force as disrupting operations on behavioral resistance to change in humans

Behavioral momentum theory (BMT) provides a theoretical and methodological framework for understanding how differentially maintained operant responding resists disruption. A common way to test operant resistance involves contingencies with suppressive effects, such as extinction or prefeeding. Other contingencies with known suppressive effects, such as response-cost procedures arranged as point-loss or increases in response force, remain untested as disruptive events within the BMT framework. In the present set of three experiments, responding of humans was maintained by point accumulation programmed according to a multiple variable-interval (VI) VI schedule with different reinforcement rates in either of two components. Subsequently, subtracting a point following each response (Experiment 1) or increasing the force required for the response to be registered (Experiments 2 and 3 decreased response rates, but responding was less disrupted in the component associated with the higher reinforcement rate. The point-loss contingency and increased response force similarly affected response rates by suppressing responding and human persistence, replicating previous findings with humans and nonhuman animals when other types of disruptive events (e.g., extinction and prefeeding) were investigated. The present findings moreover extend the generality of the effects of reinforcement rate on persistence, and thus BMT, extending the analysis of resistance to two well-known manipulations used to reduce responding in the experimental analysis of behavior.     

负性情绪调节中认知重评和分心策略的作用:ERPs研究

采用事件相关电位技术,考察了认知重评和分心两种情绪调节策略对负性情绪体验和脑电活动的影响。结果发现,认知重评后被试的负性情绪体验强度和LPP波幅(300~1300ms)比简单注视条件下低;分心后被试的负性情绪体验强度比简单注视条件下低,但LPP波幅显示比简单注视条件下高。这说明认知重评和分心对负性情绪体验和脑电活动的影响不同,负性刺激再次呈现时认知重评优于分心策略的调节。该研究为认知重评和分心的比较研究提供了神经电生理学方面的证据。     

The effects of presentation rate and retention interval on memory for items and associations in younger adults: A simulation of older adults’ associative memory deficit

Older adults show an associative deficit in episodic memory compared to younger adults. Previous research suggests both strategic and automatic binding deficits contribute to older adults’ poorer memory performance. Using behavioral manipulations designed to affect strategic and automatic binding of associations, three experiments attempted to simulate an associative deficit in younger adults. In these experiments participants learned face-scene pairs and then were given item and associative recognition memory tests. We manipulated the time allotted at encoding and retrieval to simulate strategic deficits, and the length of the retention interval to simulate automatic deficits. Results indicate that both manipulations separately contribute to a differential decline in associative memory, similar to the one shown by older adults, especially as reflected in the differential increase in false alarm rate in the associative memory test more than in the item memory test. Considerations of possible underlying brain mechanisms are discussed.     

Distal rhythm influences whether or not listeners hear a word in continuous speech: Support for a perceptual grouping hypothesis

Due to extensive variability in the phonetic realizations of words, there may be few or no proximal spectro-temporal cues that identify a word’s onset or even its presence. Dilley and Pitt (2010) showed that the rate of context speech, distal from a to-be-recognized word, can have a sizeable effect on whether or not a word is perceived. This investigation considered whether there is a distinct role for distal rhythm in the disappearing word effect. Listeners heard sentences that had a grammatical interpretation with or without a critical function word (FW) and transcribed what they heard (e.g., are in Jill got quite mad when she heard there are birds can be removed and Jill got quite mad when she heard their birds is still grammatical). Consistent with a perceptual grouping hypothesis, participants were more likely to report critical FWs when distal rhythm (repeating ternary or binary pitch patterns) matched the rhythm in the FW-containing region than when it did not. Notably, effects of distal rhythm and distal rate were additive. Results demonstrate a novel effect of distal rhythm on the amount of lexical material listeners hear, highlighting the importance of distal timing information and providing new constraints for models of spoken word recognition.     

血清Cys C的检测对肾移植术后患者肾功能评价的临床意义

探讨分析血清胱抑素C（Cys C）水平在肾移植术后患者肾功能监测中的应用价值.对25例肾移植成功患者在术前、术后第1、3、5、7、10天的血清Cys C、Scr、β2-MG、BUN水平进行动态监测,同时随机抽取健康体检者中的20例作为对照组.发现移植组的Cys C、Scr、β2-MG、BUN水平在术前均明显高于健康对照组（P＜0.01）.这四项指标在手术后第一天都有所下降,且术后第1、3、5、7、10天的水平都比术前低（P＜0.01）.四项指标与GFR的关系均为显著性负相关（P＜0.01）,其中血清Cys C与GFR的相关性最好.Cys C、Scr、β2-MG、BUN检测后的ROC曲线下面积分别是：0.937、0.838、0.798、0.772,其差异都具有统计学意义（P＜0.05）.血清Cys C优于Scr、β2-MG、BUN,在肾移植患者术后的动态监测中具有重要的临床应用价值.     

Properties of bootstrap tests for N‐of‐1 studies

N‐of‐1 study designs involve the collection and analysis of repeated measures data from an individual not using an intervention and using an intervention. This study explores the use of semi‐parametric and parametric bootstrap tests in the analysis of N‐of‐1 studies under a single time series framework in the presence of autocorrelation. When the Type I error rates of bootstrap tests are compared to Wald tests, our results show that the bootstrap tests have more desirable properties. We compare the results for normally distributed errors with those for contaminated normally distributed errors and find that, except when there is relatively large autocorrelation, there is little difference between the power of the parametric and semi‐parametric bootstrap tests. We also experiment with two intervention designs: ABAB and AB, and show the ABAB design has more power. The results provide guidelines for designing N‐of‐1 studies, in the sense of how many observations and how many intervention changes are needed to achieve a certain level of power and which test should be performed.     

对齐法在单因子和三因子多组比较中允许的不等参数率

在传统的多组验证性因子分析中,进行因子均值比较的前提条件是模型满足强测量不变性假设,但该假设在实证研究中很难满足。这时,Asparouhov和Muthén(2014)提出的对齐法是一种可供备选的多组分析法。通过蒙特卡洛模拟研究,探究了在对齐法精确估计模型参数前提下所允许的不等参数率范围。研究发现：在平均组样本量充足,识别算法为固定识别算法等理想状态下,对齐法在单因子模型多组比较中所允许的不等参数率可以是100%;在三因子模型中所允许的不等参数率上限是20%至30%;在此范围内,对齐法允许更多高程度不等参数;在组数目从30、15或9降至3时,对齐法能允许更多的不等参数在模型中。     

成功心肺复苏的合适急救团队人数的研究

探讨成功心肺复苏中合适的急救团队人数。采用回顾性分析方法,对64例实施心肺复苏成功的心搏骤停患者临床资料进行对比分析。医生3人～4人组完成高质量胸外按压（46．9％）、气管插管（42．2％）的比率高于1人～2人组（P〈0．05）,护士4人～5人组高质量完成相关操作优于2人～3人组（P〈0．05）。医师3人～4人、护士4...