Processing coordinated structures: incrementality and connectedness

We recorded participants' eye movements while they read sentences containing verb-phrase coordination. Results showed evidence of immediate processing disruption when a reflexive pronoun embedded in the conjoined verb phrase mismatched the sentence subject. We argue that this result is incompatible with models of human parsing that employ only bottom-up parsing procedures, even when flexible constituency is employed. Models need to incorporate a mechanism similar to the adjoining operation in Tree-Adjoining Grammar, in which one structure is inserted into another.     

A call to restructure the drug development process: Government over-regulation and non-innovative late stage (Phase III) clinical trials are major obstacles to advances in health care

The history of drug/vaccine development has included major advances guided primarily by risk/benefit analyses concerning the innovative agent, not by evidence-based clinical trials (Phase I–IV). Because the approval for new drugs is hindered under the present process, the system requires restructuring. The Phase I/II study period should be more flexible, using the “environment of knowledge” about the new agent, plus risk/benefit assessments. Phase III, as presently constructed, does not add new adverse events data, it provides a narrower profile of drug efficacy than properly done Phase II studies, and placebo-controlled trials continue to raise unresolved ethical and social issues. Phase III studies should be abandoned for most drugs, and substituted with properly powered Phase II doseranging studies plus careful post-marketing surveillance. Phase III should be a penalty for poor drug development, not a regulatory requirement. To accomplish efficient drug development, greater cooperation between pharmaceutical companies and governments in developing clinical trials is needed rather than over-regulation. These changes will synchronize the drug development and regulatory process with the current rapid drug discovery process, reduce drug development time and cost, and improve patient care. The author is Adjunct Professor of Medicine, Weill Medical College of Cornell University, New York, New York, USA.     

Attachment representations and characteristics of friendship relations during adolescence

Attachment theory proposes that experiences with the primary caregivers are an important basis for the development of close social relationships outside the parent-child relationship. This study examined the association between representations of attachment, as assessed with the Adult Attachment Interview (AAI), representations of friendship and peer relations, as assessed with an interview in a sample of 43 adolescents. Secure attachment representations were significantly related to interview-based assessments of close friendships, friendship concept, integration in a peer group, and emotion regulation within close friendships. Attachment experiences reported during the AAI, their integration, and their coherency were related to friendship quality and friendship concept. Results show the close associations between attachment representations and friendship relationships during adolescence. The associations between peer relations and attachment representations differed depending on whether an interview approach or a questionnaire approach was used.     

A rapid assessment of skills in young children with autism

Educational interventions based on the principles of behavior analysis are highly effective for establishing skills in young children with autism. As a first step in program development, the child's current skill level is determined by evaluating performance on tasks drawn from a preestablished curriculum. However, few specific guidelines have been delineated for conducting these skills assessments or interpreting the results. In this study, we evaluated an efficient methodology for conducting skills assessments. Six children who had been diagnosed with autism participated. The relative efficacy of two assessment packages--one containing several reinforcement procedures and one containing several potentially effective prompts--was evaluated across two to three skills for each child using multiple baseline and reversal designs. Results suggested that the methodology was useful for matching targeted skills to appropriate interventions.     

Acculturation strategies, coping process and acculturative stress

Using structural equation modeling, this study examines the influences of motivational factors (Need for Cognitive Closure--NCC--and Decisiveness), coping strategies and acculturation strategies on levels of acculturative stress. Two groups of immigrants in Rome (Croatians n= 156 and Poles n= 179) completed a questionnaire that included scales for the various factors. Although our initial hypothesized model was not confirmed, a modified model showed that the motivational factors of NCC and Decisiveness indirectly influence acculturative stress. The modified model with good fit indices indicated that the relationship between NCC and Decisiveness are mediated by coping strategies and acculturation strategies. Specifically, NCC is associated positively with avoidance coping, which in turn is negatively associated with the host group relationships and positively with the original culture maintenance. The last two dimensions predicted lower levels of acculturative stress. Decisiveness was positively associated with the problem-oriented coping and, negatively, with emotional and avoidance coping.     

Hostility and facial affect recognition: effects of a cold pressor stressor on accuracy and cardiovascular reactivity

The effects of hostility and a cold pressor stressor on the accuracy of facial affect perception were examined in the present experiment. A mechanism whereby physiological arousal level is mediated by systems which also mediate accuracy of an individual’s interpretation of affective cues is described. Right-handed participants were classified as high hostile (N=28) or low hostile (N=28) using the Cook Medley Hostility Scale. The high-hostile group met joint selection criteria. Only high-hostile participants who showed cardiovascular reactivity to the cold pressor, with systolic BP change exceeding the group mean were included. Groups were further subdivided into cold pressor and non-cold pressor test conditions. It was predicted that high-hostile men, relative to low-hostile men, would show decreased perceptual accuracy when presented with happy, angry, and neutral facial configurations within the left visual field (LVF). Results indicated that high-hostile men were less accurate than low-hostile men in the LVF. Further, pre-stress accuracy scores in the high-hostile men were similar to the post-stress accuracy scores of the low-hostile men. The lateralization of affective function and the role of physiological arousal in affective facial perception are discussed.     

What response times tell of children's behavior on the balance scale task

Analysis of accuracy of responses to balance scale problems gives a global idea of the cognitive processes that underlie problem-solving behavior on this task. We show that response times (RTs) provide additional detailed information about the kind and duration of these processes. We derive predictions about the RTs from Siegler's (1981) model for the balance scale task, including the counterintuitive prediction that young adults are slower than children in solving particular balance scale problems. The predictions were tested in a study in which 191 6- to 22-year-old participants were presented with a computerized balance scale task. RTs were analyzed with regression models. In addition to qualitative differences between items, we also modeled quantitative differences between items in the regression models. Analyses supported the predictions and provided additional knowledge on the rules. Rule II was reformulated as a rule that always involves the encoding, but not always the correct application of the distance cue. RTs provided evidence for the use of a buggy-rule and not an addition-rule. Finally, a relation between rule inconsistency and increased RT was found.     

Empathy, an integrative model

Empathy research has yielded various separate insights into empathy and its correlates. Yet a comprehensive theoretical account that situates these factors within a larger framework is lacking. In this paper a conception of empathy is proposed and defended, which makes it possible to provide an encompassing reconstruction of the processes that are characteristic of empathic encounters. This conception situates empathy within a context of communication. Doing so allows one to connect various treads in empathy research, but at the same time urges one to take new factors into account. It is argued that empathy is a response to a specific demand occurring in a specific context. The type of answer persons are able to provide depends on four types of factors. First, there are the psychological empathic components. We argue that empathy should be seen as a combination of (especially) parallel and reactive emotions, against a background of specific cognitive abilities. Second, it is argued that empathy is aided by a twofold control system, comprised of judgements and forms of self-control. Third, personality factors play a part in how a person responds to demands. Finally, but most importantly, it is pointed out that specific relational factors codetermine empathic reactions. In this paper we describe the theoretical background of our model and provide an elaborated account of the four factors that determine empathic acts in a given context. We illustrate the viability of our model by presenting observational data of children's empathic acts.     

Neuroticism,BIS, and reactivity to discrete negative mood inductions

Research has established relationships between the personality dimensions of neuroticism and BIS and broad negative emotional reactivity. However, few researchers have examined the relationships among neuroticism, BIS, and discrete negative emotional reactivities. The present study examined whether individuals scoring high on neuroticism and BIS were more reactive across four discrete negative mood inductions, relative to those scoring low on these traits. Participants (n = 166) completed personality questionnaires, measures of current mood, viewed a specific mood-inducing film clip (sadness, anger, fear or disgust) and then reported their moods a second time. Results revealed that neuroticism/BIS was associated with high reactivity to the fear and sadness inductions. Neuroticism/BIS did not predict anger or disgust reactivity, but neuroticism/BIS and extraversion/BAS interacted in predicting anger. Although further research is needed to extend generalizability, it appears that neuroticism and BIS predict negative emotional reactivity broadly, but not ubiquitously.