Rat gestation during space flight: Outcomes for dams and their offspring born after return to earth

Sprague-Dawley rats were studied to learn whether gestation in the near-zero gravity, high radiation environment of space impacts selected mammalian postnatal events. Ten rats spent days nine to twenty of pregnancy aboard the space shuttle orbiterAtlantis (STS-66). Their movement, was studied shortly after return to Earth; subsequently, several of their offspring were cross-fostered and examined through postnatal day 81 (P81) for whole body growth and somatic motor development. Values for the flight animals were compared to ground-based control groups. Relative to controls, the pregnant flight rats showed a marked paucity of locomotion during the first few hours after returning to Earth. There was greater likelihood of perinatal morbidity for the offspring of flight dams when compared to the control groups. Whole body weight of surviving offspring, averaged for each group separately, showed typical sigmoidal growth curves when plotted against postnatal age. The flight group for our study had a larger ratio of female to male pups, and that was sufficient to account for the lower average daily weight gained by the flight animals when compared to the control groups. Walking was universally achieved by P13 and preceded eye opening which was complete in all pups by P17. Thus, both of these developmental horizons were attained on schedule in the flight as well as the control rats. Characteristic changes were observed in hind limb step length and gait width as the pups grew. These patterns occurred at the same time in each group of rats. Therefore, prenatal space flight from days nine to twenty of gestation did not interfere with the establishment of normal patterns for hind paw placement during walking.     

Discomfort with space and motion: A possible marker of vestibular dysfunction assessed by the situational characteristics questionnaire

Space and motion discomfort (SMD) refers to the situational specificity of symptoms occurring in some patients with vestibular dysfunction, such as those with balance disorders and some with panic disorder. SMD occurs in situations characterized by inadequate visual or kinesthetic information for normal spatial orientation. We report the results of two studies of the construct validity of the Situational Characteristics Questionnaire (SitQ), which has two subscales, both of which measure SMD: the SMD-I and SMD-II. In Study 1, the SitQ was administered to members of a self-help group for balance disorders, a psychiatric sample consisting of patients with panic disorder, nonpanic anxiety disorders, depression, and a sample of normals. SMD levels were the highest in the self-help balance group, next to the highest in the panic groups, and lowest in the remaining groups. In Study 2, the SitQ was administered to otolaryngological patients with vestibular dysfunction and to patients with hearing loss. SMD levels were higher in the vestibular patients. Data on internal consistency, test-retest reliability, and convergent and discriminant validity are presented. The SitQ, particularly the SMD-II, is recommended for quantifying space and motion discomfort in patients with anxiety and/or balance disorders.Study 1 was funded by MH 40757. Study 2 was funded by a grant from the Upjohn Company and MH 19816.     

听障和听力正常人群空间主导性和空间参照框架的交互作用

通过要求被试分别在近处空间和远处空间完成空间参照框架的判断任务, 考察了听障和听力正常人群空间主导性和空间参照框架的交互作用。结果表明：(1)相对于听力正常人群, 听障人群完成自我参照框架判断任务的反应时更长, 而在完成环境参照框架判断任务无显著差异; (2)听障人群和听力正常人群空间主导性和空间参照框架交互作用呈现出相反模式。研究表明, 听障人群在听力功能受损后, 其空间主导性和空间参照框架的交互作用也产生了变化。     

医学影像学高等教育的发展空间探讨

根据我国医学影像学高等教育的发展历史、现状和医学影像学的人才市场分析,论证了该专业存在的空间,就其今后的发展谈了自己的看法,以期对我国医学影像学教育提供参考.     

The Epistemological Status of Vision and its Implications for Design

Computational theories of vision typically rely on the analysis of two aspects of human visual function: (1) object and shape recognition (2) co-calibration of sensory measurements. Both these approaches are usually based on an inverse-optics model, where visual perception is viewed as a process of inference from a 2D retinal projection to a 3D percept within a Euclidean space schema. This paradigm has had great success in certain areas of vision science, but has been relatively less successful in understanding perceptual representation, namely, the nature of the perceptual encoding. One of the drawbacks of inverse-optics approaches has been the difficulty in defining the constraints needed to make the inference computationally tractable (e.g. regularity assumptions, Bayesian priors, etc.). These constraints, thought to be learned assumptions about the nature of the physical and optical structures of the external world, have to be incorporated into any workable computational model in the inverse-optics paradigm. But inference models that employ an inverse optics plus structural assumptions approach inevitably result in a naïve realist theory of perceptual representation. Another drawback of inference models for theories of perceptual representation is their inability to explain central features of the visual experience. The one most evident in the process and visual understanding of design is the fact that some visual configurations appear, often spontaneously, as perceptually more coherent than others. The epistemological consequences of inferential approaches to vision indicate that they fail to capture enduring aspects of our visual experience. Therefore they may not be suited to a theory of perceptual representation, or useful for an understanding of the role of perception in the design process and product.     

Time,space, and process in Anne Conway

ABSTRACT

Many scholars have drawn attention to the way that elements of Anne Conway’s system anticipate ideas found in Leibniz. This paper explores the relationship between Conway and Leibniz’s work with regard to time, space, and process. It argues – against existing scholarship – that Conway is not a proto-Leibnizian relationist about time or space, and in fact her views lie much closer to those of Henry More; yet Conway and Leibniz agree on the primacy of process. This exploration advances our understanding of Conway’s system, and the intellectual relationships between Conway, More, and Leibniz.     

Creating a dialogic space for prospective teacher critical reflection and transformative learning

This research highlights the pedagogical significance of dialogic spaces in supporting critical reflection and transformative learning among prospective teachers in the United States. It finds that, with elucidation of the multiple voices and texts from prospective teachers’ field experience, teacher educators can stimulate deep reflection to springboard transformative learning. It also finds that ePortfolios have strong potential to support a dialogic approach to reflection. However, it is also clear that, absent systematic observation and careful follow-up dialogue, the potential to move from reflection to transformative learning is limited. The findings will help teacher educators rethink the design and practice of supervision with ePortfolios, reinforcing that critical dialogue between the supervisor and the prospective teachers is key to supporting prospective teachers’ critical reflection and transformative learning, and to improving their teaching practice.     

‘Pre-crime’, Prevent,and practices of exceptionalism: Psychotherapy and the new norm in the NHS

Section ’26 of the Counter-Terrorism and Security Act 2015 places a duty on local authorities and public sector institutions to have ‘due regard to the need to Prevent people from being drawn into terrorism’. Accordingly, NHS staff are now required to attend a Workshop to Raise Awareness of Prevent (WRAP), ensuring they are trained to spot the ideological symptoms and psychosocial vulnerabilities thought to predict extremist activity. In this paper, I suggest that the insertion of counter-radicalisation duties into the work of psychotherapists and other mental health professionals is not simply to be understood as an attempt to forestall and avert extremist activity. Rather, drawing on the work of Georgio Agamben and Judith Butler, I argue it can be viewed as an innovative tactic of governmentality whose technologies of surveillance ensure a culture of conformity in the NHS through which a ‘state of exception’ can be established and normalised. I illuminate this by examining two interrelated aspects of the Prevent duty: one, the decision by the government to embed Prevent within the existing rhetoric and practice of ‘safeguarding vulnerable children and adults’; and two, its discursive representation of the consulting room as ‘pre-criminal space’. I conclude by suggesting that the government’s determination to allow ‘no ungoverned space in which extremism is allowed to flourish’ targets the limits of acceptable speech and so the very conditions for radical thought and critique on which psychotherapy depends.