A clinical trial of continuous, intermittent and overlearning ‘bell and pad’ treatments for nocturnal enuresis

Sixty-one enuretic children were allocated sequentially to ‘standard’, ‘intermittent’ or ‘overlearning’ bell and pad treatment. The results suggest that the ‘overlearning’ modification of standard treatment was successful in bringing about a reduction in the relapse rate. The present status and implications of research into nocturnal enuresis were discussed in the light of the results of the investigation.     

Child judgments of sentences varying in grammatical complexity

This study is another contribution to the development of a satisfactory child version of the linguistic task of judging grammaticality. With a nondifferentially reinforced forced-choice procedure, it was found that responses of 24 5- and 24 7-yr-old children did vary as a function of the grammatical complexity of stimulus sentences. The children judged sentence stimuli of two types (negatives and wh-word questions) each having three levels of grammatical complexity (two primitive and one well-formed). After each stimulus presentation, the subject pointed to the adult or the child in a photograph, depending on who was judged to have produced that utterance. Performance of the two age groups did not differ for the question stimuli, for which subjects pointed to the adult more frequently as the grammatical complexity of wh-word questions increased. In response to the negative sentences, the older group attributed more well-formed stimuli to the adult than primitive ones. While the younger group pointed to the adult more frequently for well-formed negatives than for the middle level negatives, they made more adult responses than expected to the least complex negatives. It was concluded that, with this procedure, 5- and 7-yr-olds demonstrate ability to distinguish grammatically well-formed from primitive sentences. Procedural improvements for future research may allow children this age and younger to demonstrate more adult-like discrimination between a variety of primitive and well-formed sentences.     

Augmentation of eating following a signal for feeding in rats

Previous studies have shown that a CS for feeding produces increases in some measures of excitation, but effects on other behaviors have not been examined. Two experiments examined effects on eating. In each experiment, one group of rats was presented with a CS preceding feeding, while control groups had no anticipatory signal. Ss with signaled feeding learned to eat more than control Ss, and their body weights were relatively higher. These results indicate that conditioned incentive stimuli may have broader effects than have classically been attributed to them. It is also suggested that learned factors may mediate the effects of deprivation operations on eating and play a significant part in the regulation of feeding.     

Infantile stimulation and its effects on frustration- and fear-motivated behavior in rats

Infant rats that were either removed from the nest each day (handled) or left undisturbed (nonhandled) were, in adulthood, given 72 food-reinforced runway acquisition trials followed by 24 trials of extinction training with or without shock. Handled and nonhandled control animals were given runway training without food reinforcement. Reinforced rats ran faster than nonreinforced rats, and handled rats ran faster than nonhandled rats during the initial trials of runway acquisition irrespective of the reinforcement condition. Nonhadled rats stopped running sooner than handled rats when shock was introduced in the goalbox, but differences between handled and nonhandled rats given extinction training without shock were small. Results of a second experiment showed no differences between handled and non-handled rats in the magnitude of the depression effect after an incentive shift. It was concluded that infantile handling had little effect on frustration-motivated behavior, but did affect fear-motivated behavior.     

Visual imagery and dream recall

Research in dream recall frequency has failed to isolate psychological variables which clearly and reliably differentiate frequent dream recallers from infrequent recallers. The present study tested the hypothesis that frequent recallers have a greater capacity for visual imagery than infrequent recallers. Subjects selected on the basis of reported dream recall frequency were administered a Paired-Associate Learning task designed to measure visual imagery, a rating scale of imagery clarity and vividness, and a subjective measure of imagery controllability. The results provide support for the hypothesis and, together with other evidence, suggest that a generalized capacity for visualization may contribute to the quality of the dreaming experience and, consequently, to its recallability.     

Some processes in children's comprehension of linguistically and visually depicted relationships

A type of paired-associate task was given to 64 kindergarteners and 64 fifth-graders. In four conditions both linguistic and pictorial stimuli were presented simultaneously. In one condition, both a linguistic and pictorial relationship between two objects was depicted; in a second, only the linguistic aspect of the stimuli depicted a relationship; in the third condition, only the picture was relational; and in the fourth, neither the sentences nor the pictures portrayed a relationship between the objects. The results indicate that a relationship in both modes facilitated recall more than the presentation of a relationship in only one mode. A relationship in either mode enhanced recall more than no relationship at all. There were general significant age and IQ effects. The results are interpreted as favoring a duo-system model, with both representation and comprehension occurring within the context of relatively independent systems.     

走出慢性乙型、丙型病毒性肝炎诊断的误区

我国病毒性肝炎是一个非常重要的肝病,病毒性肝炎的诊断不仅依靠临床表现,肝功能指标的改变,也依赖于病毒标志物的检测。病毒血清学检查是确定诊断的唯一标准。乙、丙、丁型病毒性肝炎的血清标志物项目繁多,临床意义相差较大,正确理解能为诊断提供很大帮助。     

通过打破抗原特异性T细胞免疫耐受控制慢性HBV感染

乙型肝炎病毒(HBV)感染诱导机体抗病毒免疫应答,若不能对病毒有效清除,体内抗原特异的CTL降低,出现抗原特异性T细胞免疫耐受,造成慢性肝脏炎症。分析HBV感染时抗原特异性T细胞免疫耐受机制,并通过打破免疫耐受预防HBV感染。