The first year after diagnosis: psychological impact on people with multiple sclerosis

The impact of multiple sclerosis (MS) diagnosis on newly diagnosed individuals remains so far little explored. Our aim is to outline affective, personality and quality of life (QoL) correlates of MS patients shortly after MS diagnosis. Thirty-eight (22 F and 16 M) newly-diagnosed MS patients (mean interval from diagnosis communication 4.7 ± 3.8 months, range 1–12 months) underwent the Montgomery–Åsberg Depression Rating Scale and a comprehensive psychological evaluation: Beck Depression Inventory-II, State-Trait Anxiety Inventory, Psychophysiological Questionnaire-Revised, Fear Survey Schedule, Maudsley Obsessional-Compulsive Questionnaire, Impact of Event Scale-Revised, Personal Meaning Questionnaire, Problem Solving Inventory and Multiple Sclerosis Quality of Life-54. The Expanded Disability Status Scale was assessed during the neurological examination. Depressive symptomatology, only partially related to disability, was observed in approximately 40% of patients. The prevalent approach to MS diagnosis was one of avoidance in 65.8% of cases. QoL reductions in self-perception and psychological well-being emerged, together with a peculiar perception of change in health that was not related to neurological disability. With regard to personality assessment, depressive personal meaning organization correlates inversely with important QoL measures. Newly-diagnosed patients go through a complex network of psychological changes still in the initial phases immediately after diagnosis. A thorough understanding of these adjusting aspects by the neurologist could be crucial in improving patients’ QoL, participation in relevant disease decisions and adherence to pharmacological therapy.     

Diabetes and psychological co-morbidity in children with a family history of early-onset type 2 diabetes

The present study was conducted to evaluate for depressive symptoms and undiagnosed diabetes in children with familial history of early-onset type 2 diabetes. Studies have shown that diabetes doubles the risk for depression and that the duration of diabetes is related to the severity of the depression. Individuals with depression are also said to be at greater risk for developing diabetes. In many cases diabetes is detected whilst screening for depression. Fifty-three children aged between 6 and 17 years were screened for diabetes and assessed for depressive symptoms using the Children Depression Rating Scale, revised version (CDRS-R). Thirty-six (68.0 %) of the children with a family history of early-onset type 2 diabetes had CDRS-R scores consistent with likely or very likely major depressive disorders. Depressive symptoms score was predicted best by the number of generations of diabetes in the family, with an associated r = .65 and adjusted R(2) = .41. As the generations of diabetes increased, the more likely it was for a child to have diabetes (r = .38, p = .005). Four (7.5%) of the children were diagnosed with diabetes. The findings suggest that depressive symptoms are common in children with a family history of early onset type 2 diabetes and may co-exist with diabetes. The independent variable that reliably predicted the child depressive symptoms score was the number of generations of diabetes in the family.     

Freeze-Frame: a new infant inhibition task and its relation to frontal cortex tasks during infancy and early childhood

The current study investigated a new, easily administered, visual inhibition task for infants termed the Freeze-Frame task. In the new task, 9-month-olds were encouraged to inhibit looks to peripheral distractors. This was done by briefly freezing a central animated stimulus when infants looked to the distractors. Half of the trials presented an engaging central stimulus, and the other half presented a repetitive central stimulus. Three measures of inhibitory function were derived from the task and compared with performance on a set of frontal cortex tasks administered at 9 and 24 months of age. As expected, infants' ability to learn to selectively inhibit looks to the distractors at 9 months predicted performance at 24 months. However, performance differences in the two Freeze-Frame trial types early in the experiment also turned out to be an important predictor. The results are discussed in terms of the validity of the Freeze-Frame task as an early measure of different components of inhibitory function.     

Fostering Taiwanese preschoolers’ understanding of the addition–subtraction inverse principle

The present research involved gauging preschoolers’ learning potential for a key arithmetic concept, the addition–subtraction inverse principle (e.g., 2 + 1 − 1 = 2). Sixty 4- and 5-year-old Taiwanese children from two public preschools serving low- and middle-income families participated in the training experiment. Half were randomly assigned to an experimental group; half, to a control condition. Participants were tested for an understanding of inversion before and after intervention. One-third of the 5 year olds from both groups performed at the marginally or reliably successful levels before the intervention, and three quarters of them did so in the posttest. Only one of the 4 year olds was marginally successful before the intervention and 4 year olds in the experimental group somewhat benefited from the intervention. Significant social class effect were evident.     

The impact of early maternal verbal scaffolding and child language abilities on later decoding and reading comprehension skills

This study examined, via structural equation modeling, early predictors of children's 8 year reading decoding and 10 year comprehension at later school age. Maternal verbal scaffolding indirectly influenced both decoding and comprehension, through its support of children's language abilities at 3 and 4 years of age. Additionally, there was a trend for a direct effect of 4 year child language on reading comprehension at 10 years. As maternal verbal scaffolding was assessed during every day routines, this suggests that rich language input in the broad social context of the home promotes language and, in turn, later reading skills. Given that maternal verbal scaffolding can be enhanced through interventions, these results have important educational implications.     

Further development of measures of early math performance for preschoolers

The purpose of this study was to examine the progress monitoring and screening accuracy for a set of curriculum-based measures (CBM) of early mathematics skills. Measures included counting objects, selecting numbers, naming numbers, counting, and visual discrimination. Measures were designed to be administered with preschoolers in a short period of time using a developmentally appropriate format, and to constitute minimal disruption to the classroom routine. Previous research indicated that each of these measures produced scores with acceptable consistency across alternate forms on consecutive days. Scores yielded on the experimental probes correlated moderately, in most cases, with two commonly used standardized measures (i.e., the Brigance Screens and TEMA-2). Performance on the probes also correlated with teacher rankings and ratings of child performance. In the present study, data were collected in two phases. In the first phase, a cohort of children were administered the early math measures in spring of preschool and were followed into winter of kindergarten where they were administered kindergarten CBM probes to examine the degree to which performance in preschool (as measured by the early math probes) could predict performance on similar tasks in kindergarten. Second, risk criteria were examined and compared to identification by the Brigance Screens. These analyses provided data about the potential accuracy of the probes for screening. In the second phase, sensitivity of the probes to performance differences was examined by comparing mean performance on the probes of preschoolers and kindergartners. The lowest-performing children were provided with seven intervention sessions to examine the degree to which probes could detect growth resulting from intervention. Directions for future research and implications for practice are discussed.     

Young children's comprehension of English SVO word order revisited: Testing the same children in act-out and intermodal preferential looking tasks

Act-out and intermodal preferential looking (IPL) tasks were administered to 67 English children aged 2–0, 2–9 and 3–5 to assess their comprehension of canonical SVO transitive word order with both familiar and novel verbs. Children at 3–5 and at 2–9 showed evidence of comprehending word order in both verb conditions and both tasks, although children at 2–9 performed better with familiar than with novel verbs in the act-out task. Children at 2–0 showed no evidence of comprehending word order in either task with novel verbs; with familiar verbs they showed competence in the IPL task but not in the act-out task. The difference in performance for familiar and novel verbs from the same children at 2–0, on the IPL task, and at 2–9, on the act-out task, is consistent with the hypothesis that early linguistic/cognitive representations are graded in strength, with early representations still weak and very task dependent. However, these representations also become more abstract with development, as indicated by the familiarity effect even in the more sensitive IPL task.     

Does syntax play a role in Theory of Mind development before the age of 3 years?

Language plays an important role in Theory of Mind development. Specifically, longitudinal and training studies indicate that the acquisition of complement syntax has an effect on three- to five-year-old children’s mastery of the concept of false belief. There is evidence for both a beginning explicit understanding of the mind and mastery of complement syntax in children before their third birthday. In the present study, we investigated longitudinally whether an early sensitivity to complement syntax is related to early development of Theory of Mind abilities in a sample of N = 159 German-speaking 27- to 36-month-old children. Children’s sensitivity to formal properties of complement syntax at 33 months was associated with their perspective-taking skills and their metacognition of own ignorance three months later. This relation remained significant when controlling for the effects of general language abilities. Furthermore, children’s sensitivity to complement syntax was concurrently related to their early false belief understanding. These findings support the view that complement syntax shares representational demands with an understanding of epistemic states and that language begins to support the acquisition of epistemic concepts earlier than was previously thought.     

Screen use before bedtime: Consequences for nighttime sleep in young children

There is increasing interest in the relation between screen use and sleep problems in early childhood. In a sample of 30-month-old children, this study used observational measures of screen use during the hour or so leading up to bedtime, parent reports of screen use during the child’s bedtime routine, and actigraphic measures of toddler sleep to complement parent-reported sleep problems. Whether screen use was observed during the pre-bedtime period or was reported by the parents as part of the nightly bedtime routine, greater screen use in either context was associated with more parent-reported sleep problems. Additionally, more frequent parent-reported screen use during the bedtime routine was also associated with actigraphic measures of later sleep, shorter sleep, and more night-to-night variability in duration and timing of sleep. These associations suggest the negative consequences of screen use for children’s sleep extend both to aspects of sleep reported by parents (e.g., bedtime resistance, signaled awakenings) and to aspects measured by actigraphy (e.g., shorter and more variable sleep).