Executive functioning and processing speed in age-related differences in time estimation: a comparison of young,old, and very old adults

Age-related differences in time estimation were examined by comparing the temporal performance of young, young–old, and old–old adults, in relation to two major theories of cognitive aging: executive decline and cognitive slowing. We tested the hypothesis that processing speed and executive function are differentially involved in timing depending on the temporal task used. We also tested the assumption of greater age-related effects in time estimation in old–old participants. Participants performed two standard temporal tasks: duration production and duration reproduction. They also completed tests measuring executive function and processing speed. Findings supported the view that executive function is the best mediator of reproduction performance and inversely that processing speed is the best mediator of production performance. They also showed that young–old participants provide relatively accurate temporal judgments compared to old–old participants. These findings are discussed in terms of compensation mechanisms in aging.     

Timing recalibration in childhood Tourette syndrome associated with persistent pimozide treatment

In this study, we have tested the effects of the dopamine D₂ receptor blocker pimozide on timing performance in patients with Tourette syndrome (TS). Nine children with TS were tested off‐medication and following 3 months of daily treatment with pimozide. Subjects completed a time reproduction and a time production task using supra‐second temporal intervals. We show that pimozide improves motor timing performance by reducing the patients' variability in reproducing the duration of visual stimuli. On the other hand, this medication has no effect on the reproduction accuracy and on both variability and accuracy of the performance on the time production task. Our results suggest that pimozide might have improved motor timing variability as a result of its beneficial side effect on endogenous dopamine levels (i.e., normalization).     

Just Ignore It? Parents and Genetic Information

This paper discusses whether prospectiveparents ought to find out about their geneticconstitution for reproductive reasons. It isargued that ignoring genetic information can bein line with responsible parenthood or perhapseven recommendable. This is because parenthoodis essentially an unconditional project inwhich parents ought to commit themselves tonurturing any kind of child. Besides, thetraditional reasons offered for theunfortunateness of impairments and the tragicfate of families with disabled children are notconvincing. Other morally problematic outcomesof genetics, such as discrimination againstindividuals with impairments, and limiting freeparental decision making, are alsoconsidered.     

The effect of Parkinson's disease on time estimation as a function of stimulus duration range and modality

The present research sought to investigate the role of the basal ganglia in timing of sub- and supra-second intervals via an examination of the ability of people with Parkinson's disease (PD) to make temporal judgments in two ranges, 100-500 ms, and 1-5 s. Eighteen non-demented medicated patients with PD were compared with 14 matched controls on a duration-bisection task in which participants were required to discriminate auditory and visual signal durations within each time range. Results showed that patients with PD exhibited more variable duration judgments across both signal modality and duration range than controls, although closer analyses confirmed a timing deficit in the longer duration range only. The findings presented here suggest the bisection procedure may be a useful tool in identifying timing impairments in PD and, more generally, reaffirm the hypothesised role of the basal ganglia in temporal perception at the level of the attentionally mediated internal clock as well as memory retrieval and/or decision-making processes.     

A Heideggerian Defense of Therapeutic Cloning

Debates about the legitimacy of embryonic stem-cell research have largely focused on the type of ethical value that should be accorded to the human embryo in␣vitro. In this paper, I try to show that, to broaden the scope of these debates, one needs to articulate an ontology that does not limit itself to biological accounts, but that instead focuses on the embryo’s place in a totality of relevance surrounding and guiding a human practice. Instead of attempting to substantiate the ethical value of the embryo exclusively by pointing out that it has potentiality for personhood, one should examine the types of practices in which the embryo occurs and focus on the ends inherent to these practices. With this emphasis on context, it becomes apparent that the embryo’s ethical significance can only be understood by elucidating the attitudes that are established towards it in the course of specific activities. The distinction between fertilized embryos and cloned embryos proves to be important in this contextual analysis, since, from the point of view of practice, the two types of embryos appear to belong to different human practices: (assisted) procreation and medical research, respectively. In my arguments, I highlight the concepts of practice, technology, and nature, as they have been analyzed in the phenomenological tradition, particularly by Martin Heidegger. I come to the conclusion that therapeutic cloning should be allowed, provided that it turns out to be a project that benefits medical science in its aim to battle diseases. Important precautions have to be taken, however, in order to safeguard the practice of procreation from becoming perverted by the aims and attitudes of medical science when the two practices intersect. The threat in question needs to be taken seriously, since it concerns the structure and goal of practices which are central to our very self understanding as human beings.     

时距估计年龄差异的认知机制

采用双任务的实验范式,通过对（5s、13s和26s）三个目标时距的产生法和复制法的结果来探讨时距估计年龄差异的认知机制。实验结果表明,在不同目标时距和不同的估计方法上均存在显著的年龄效应。年老被试在产生法上比年轻被试显著高估时距,存在非时间任务和年龄的交互作用,随着任务难度的增加年老被试会比年轻被试产生更长的时距。而在复制法上年老被试比年轻被试显著低估时距,但是只有在长时距条件下（26s）存在非时间任务和年龄的交互作用。本研究结果表明年老被试在产生法上对时距的高估可能与内部时钟减慢和注意资源减少有关,而在复制法上对时距的低估可能反映注意资源的减少。此外,对于长时距的时间复制,情节记忆的损伤也是导致时距估计年龄差异的一个可能原因。     

Rank and reproduction among female langur monkeys: Aging and improvement (They're not just getting older,they're getting better)

An investigation of the social rank, reproduction, and ages of adult female Indian gray langur monkeys (Presbytis entellus) living in two colony social groups revealed that rank based on displacements is neither correlated with nor best predicted by female age or reproductive value. The hierarchy of female ranks is best conceptualized as a layered ranking system in which there are clusters of females of the same dominance rank forming layers within the structure. Statistical significance in frequencies of displacement differs between but not within these layered groups of females. Factors such as group composition, presence of uterine kin, reproductive state, and individual personality are hypothesized to predict changes in female rank far better than does reproductive value. Our data show that reproductive success increases with age. The infant survival record for the six oldest females in our colony was much better than for the five youngest adult females.     

Ethnography and Jewish Ethics

This essay offers a Jewish approach to ethnography in religious ethics. Following the work of other ethnographers working in religious ethics, I explore how an ethnographic account of reproductive ethics among Haredi (ultra‐Orthodox) Jewish women in Jerusalem enhances and improves Jewish ethical discourse. I argue that ethnography should become an integral part of Jewish ethics for three reasons. First, with a contextual approach to guidance and application of law and norms, an ethnographic approach to Jewish ethics parallels the way ethical decisions are made on a daily basis in Jewish communities. Second, ethnography bolsters the voices of those involved in ethical discourse. Third, ethnography facilitates the bridge between local ethical questions and global ethical discourse.     

The maintenance of cultural stereotypes in the conversational retelling of narratives

Interpersonal communication plays a significant role in the maintenance of culturally shared stereotypes. This paper reports on two experiments in which two different stories were transmitted conversationally through communication chains. In both experiments, people tended to emphasize more stereotype consistent than stereotype inconsistent (SI) information, thus rendering the stories more confirming, rather than challenging, of the stereotypes. Although SI information sometimes attracted more attention in conversation, this did not translate into a greater likelihood of passing on SI information, thus keeping the story character's impression largely stereotypical even after a second retelling of the story.