Idiographic network analysis of discrete mood states prior to treatment

Idiographic network models based on time‐series data have received recent attention for their ability to model relationships among symptoms and behaviours as they unfold in time within a single individual (cf. Epskamp, Borsboom, & Fried, 2018; Fisher, Medaglia, & Jeronimus, 2018). Rather than examine the correlational relationships between variables in a sample of individuals, an idiographic network examines correlations within a single person, averaged over many time points. Because the approach averages over time, the data must be stationary (i.e. relatively consistent over time). If individuals experience varying states over time—different mixtures of symptoms and behaviours in one moment or another—then averaging over categorically different moments may undermine model accuracy. Fisher and Bosley (2019) address these concerns via the application of Gaussian finite mixture modelling to identify latent classes of time points in intraindividual time‐series data from a sample of adults with major depressive disorder and/or generalised anxiety disorder (n = 45). The present paper outlines an extension of this work, wherein network analysis is used to model within‐class covariation of symptoms. To illustrate this approach, network models were constructed for each intraindividual class identified by Fisher and Bosley (137 networks across the 45 participants, mean classes/person = ~3, range = 2–4 classes/person). We examine the relative consistency in symptom organisation between each individual's multiple mood state networks and assess emergent group‐level patterns. We highlight opportunities for enhanced treatment personalisation and review nomothetic patterns relevant to transdiagnostic conceptualisations of psychopathology. We address opportunities for integrating this approach into clinical practice and outline potential shortcomings.     

视觉工作记忆中的内部注意选择：效果、特性及机制

视觉工作记忆中(VWM)已稳定存储的表征,依然会受内部注意选择的影响,说明内部注意选择对VWM发挥重要作用。本文首先阐述该领域主要的研究方法,然后对VWM中内部注意选择的效果和四个特性：时程、对象、容量和可持续性,以及其背后可能的理论机制和神经机制进行分析和总结。并据此从VWM的存储结构、内部注意的产生机制和处理方式等方面,为未来研究提出方向和建议。     

中英双语者情绪注意偏向中的双语优势效应

采用改进的点–探测范式,考察熟练双语者在情绪注意偏向中对情绪信息加工的优势效应及该效应产生的原因。采用2（熟练双语者和非熟练双语者）×3（靶刺激与消极词汇出现的位置一致、不一致和中性条件）×2（线索呈现时间为100 ms和400 ms）的混合实验设计,记录被试对靶子的按键反应时和错误率。结果发现：线索呈现100 ms和400 ms时,两组被试在注意定向分数上无显著差异;线索呈现100 ms时,两组被试的注意解除分数无显著差异;线索呈现400 ms时,熟练双语者的注意解除分数显著小于非熟练双语者。结果表明,在情绪注意偏向任务中,熟练双语者比非熟练双语者表现出了对情绪词汇信息更好的注意抑制控制能力,体现出对情绪信息加工的双语优势效应,产生这一优势效应的原因是熟练双语者在注意的晚期阶段比非熟练双语者具有更好的情绪信息注意解除能力。     

青少年的同伴选择与同伴影响：基于学业投入与学业成就的纵向社会网络分析

以756名中学生为研究对象,对学业投入、学业成就、同伴团体进行追踪测量,探讨青少年同伴团体的学业投入及学业成就是否存在同伴选择与同伴影响效应。结果表明：（1）在1年的追踪时间中,青少年学业投入的发展呈下降趋势,初始水平与下降速度负相关,学业成就的发展呈上升趋势,初始水平与上升速度无显著相关;（2）学业投入与学业成就存在同伴选择效应,青少年倾向选择与自己学业投入及学业成就相似的个体构建同伴团体;（3）青少年的学业投入及学业成就与同伴逐渐趋近相似,即同伴影响效应显著。     

Behavior analysis and revaluation

Revaluation refers to phenomena in which the strength of an operant is altered by reinforcer-related manipulations that take place outside the conditioning situation in which the operant was selected. As an example, if lever pressing is acquired using food as a reinforcer and food is later paired with an aversive stimulus, the frequency of lever pressing decreases when subsequently tested. Associationist psychology infers from such findings that conditioning produces a response-outcome (i.e., reinforcer) association and that the operant decreased in strength because pairing the reinforcer with the aversive stimulus changed the value of the outcome. Here, we present an approach to the interpretation of these and related findings that employs neural network simulations grounded in the experimental analysis of behavior and neuroscience. In so doing, we address some general issues regarding the relations among behavior analysis, neuroscience, and associationism.     

Psychosocial Treatment Strategies in the MTA Study: Rationale, Methods, and Critical Issues in Design and Implementation

The Collaborative Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder (ADHD), the MTA, is the first multisite, cooperative agreement treatment study of children, and the largest psychiatric/psychological treatment trial ever conducted by the National Institute of Mental Health. It examines the effectiveness of Medication vs. Psychosocial treatment vs. their combination for treatment of ADHD and compares these experimental arms to each other and to routine community care. In a parallel group design, 579 (male and female) ADHD children, aged 7–9 years, 11 months, were randomly assigned to one of the four experimental arms, and then received 14 months of prescribed treatment (or community care) with periodic reassessments. After delineating the theoretical and empirical rationales for Psychosocial treatment of ADHD, we describe the MTA's Psychosocial Treatment strategy applied to all children in two of the four experimental arms (Psychosocial treatment alone; Combined treatment). Psychosocial treatment consisted of three major components: a Parent Training component, a two-part School Intervention component, and a child treatment component anchored in an intensive Summer Treatment Program. Components were selected based on evidence of treatment efficacy and because they address comprehensive symptom targets, settings, comorbidities, and functional domains. We delineate key conceptual and logistical issues faced by clinical researchers in design and implementation of Psychosocial research with examples of how these issues were addressed in the MTA study.Deceased     

Do Executive Function Deficits Differentiate Between Adolescents with ADHD and Oppositional Defiant/Conduct Disorder? A Neuropsychological Study Using the Six Elements Test and Hayling Sentence Completion Test

Two neuropsychological measures of executive functions—Six Elements Tests (SET) and Hayling Sentence Completion Test (HSCT)—were administered to 110 adolescents, aged 12–15 years. Participants comprised four groups: Attention Deficit Hyperactivity Disorder (ADHD) only (n = 35), ADHD and Oppositional Defiant Disorder/Conduct Disorder (ODD/CD) (n = 38), ODD/CD only (n = 11), and a normal community control group (n = 26). Results indicated that adolescents with ADHD performed significantly worse on both the SET and HSCT than those without ADHD, whether or not they also had ODD/CD. The adolescents with ADHD and with comorbid ADHD and ODD/CD were significantly more impaired in their ability to generate strategies and to monitor their ongoing behavior compared with age-matched controls and adolescents with ODD/CD only. It is argued that among adolescents with clinically significant levels of externalizing behavior problems, executive function deficits are specific to those with ADHD. The findings support the sensitivity of these two relatively new tests of executive functions and their ecological validity in tapping into everyday situations, which are potentially problematic for individuals with ADHD.     

Testing the ability of children with attention deficit hyperactivity disorder to accurately report the effects of medication on their behavior

Children with attention deficit hyperactivity disorder (ADHD) are often treated with central nervous system stimulants, making the evaluation of medication effects an important topic for applied behavior analysts. Because assessment protocols emphasize informant reports and direct observations of child behavior, little is known about the extent to which children themselves can accurately report medication effects. Double-blind placebo-controlled procedures were used to examine whether 6 children with ADHD could recognize the effects of their medication. The children were given math worksheets to complete for 15 min during each of 14 sessions while on medication and placebo. Children completed a self-evaluation form at the end of each session, and ratings were compared to observed behavior and academic performance. Results indicated that 3 children were able to accurately report their medication status at levels greater than chance, whereas the accuracy of reports by all children was related to dosage level, differences in behavior, and the presence of adverse effects. The implications of these results for placebo-controlled research, self-monitoring of dosage levels, and accuracy training are discussed.     

Effects of methylphenidate on sensitivity to reinforcement in children diagnosed with attention deficit hyperactivity disorder: an application of the matching law

The behavior of children diagnosed with attention deficit hyperactivity disorder (ADHD) has been hypothesized to be the result of decreased sensitivity to consequences compared to typical children. The present study examined sensitivity to reinforcement in 2 boys diagnosed with ADHD using the matching law to provide more precise and quantitative measurement of this construct. This experiment also evaluated the effects of methylphenidate (MPH) on sensitivity to reinforcement of children with ADHD. Subjects completed math problems to earn tokens under four different variable-interval (VI) schedules of reinforcement presented in random order under both medicated and nonmedicated conditions. Results showed that, in the medicated condition, the matching functions for both subjects resulted in higher asymptotic values, indicating an overall elevation of behavior rate under these conditions. The variance accounted for by the matching law was also higher under the medicated conditions, suggesting that their behavior more closely tracked the changing rates of reinforcement while taking MPH compared to placebo. Under medicated conditions, the reinforcing efficacy of response-contingent tokens decreased. Results are discussed with respect to quantifying behavioral changes and the extent to which the drug interacts with prevailing contingencies (i.e., schedule values) to influence behavioral variability.