老年糖代谢异常患者血浆NT—proBNP与血管内皮功能早期监测意义

通过检测老年糖代谢异常患者的血浆N末端血清脑钠肽前体（NT—proBNP）水平与肱动脉血管内皮依赖性舒张功能（FMD）,探讨其早期监测意义。共77例观察对象,其中12例血糖正常的健康老人为对照组,65例老年糖代谢异常组患者根据空腹血糖（FBG）和糖耐量2小时（0GTT2h）血糖水平分为空腹血糖受损组（IFG）14例、糖耐量受损组（IGT）23例和2型糖尿病组（DM）28例。各组均检测血浆NT—proBNP水平和无创超声监测FMD。随着血糖代谢异常程度加重,比较正常组,糖代谢异常组的血浆NT—proBNP水平升高（P〈0．01）,FMD调节下降（P〈0．01）;糖代谢异常发展过程中,IFG阶段FMD即出现舒张失调（P〈0．05）;IGT阶段血浆NT-proBNP水平升高有意义并达到无症状心衰诊断标准（P〈0．01）,且FMD出现舒张过度调节,提示收缩和舒张功能双向调节不良。空腹血糖升高增加血管内皮依赖性舒张功能损害,当FBG合并（或）餐后血糖升高,血浆NT—proBNP水平升高可以成为早期预测慢性无症状心功能不全的危险因素。因此,关注老年糖代谢异常早期阶段进程,并联合血浆NT—proBNP水平和血管内皮依赖性舒张功能监测,不仅对靶器官保护具有早期预警意义,而且是临床控制血糖管理的重要而简易的方法之一。     

学习时间在重复学习范式中的监测功能

通过让被试在自定步速的学习条件下完成重复学习任务,考察在重复学习范式中学习时间的监测功能。研究发现：在两次学习中,学习时间与学习判断等级和回忆成绩均有显著负相关;在第二次学习中,线索有效性不变,而随着线索利用率的提高,学习判断预测的准确性也显著提高。研究结果验证了学习时间的监测功能。     

A Jungian contribution to a dynamic systems understanding of disorganized attachment

This panel emerged from shared clinical concerns when working with adult patients whose presentation style was reminiscent of a disorganized (Type D) infant attachment pattern. Psychotherapeutic work with such patients poses complicated transference and countertransference dilemmas which are addressed by all four panellists via theory and clinical vignettes. In common is an interest in contemporary attachment, neuroscience and trauma theories and their relationship to analytical psychology. Intergenerational trauma seems to be a salient factor in the evolution of fragmented and fragmenting interactions that lead to failures in self-coherence and healthy interpersonal relationships. Such early relational trauma is compounded by further episodes of abuse and neglect leading to failure in a core sense of self. These clinicians share how they have integrated theory and practice in order to help dissociated and disorganized patients to transform their dark and extraordinary suffering through implicit and explicit experiences with the analyst into new, life giving patterns of relationship with self and others. The alchemy of transformation, both positive and negative, is evident in the case material presented.     

Deconstructing the tower: Parameters and predictors of problem difficulty on the Tower of London task

The Tower of London (TOL) task has been widely used in both clinical and research realms. In the current study, 104 healthy participants attempted all possible moderate- to high-difficulty TOL problems in order to determine: (1) optimal measures of problem solving performance, (2) problem characteristics, other than the minimum moves necessary to solve the problem, that determine participants’ difficulty in solving problems successfully, quickly, and efficiently, and (3) effects of increased task experience on which problem characteristics determine problem difficulty. A factor analysis of six performance measures found that, regardless of task experience, problem difficulty could be captured well either by a single factor corresponding to general quality of solution or possibly by three subordinate factors corresponding to solution efficiency, solution speed, and initial planning speed. Regression analyses predicting these performance factors revealed that in addition to a problem’s minimum moves three problem parameters were critical in determining the problem difficulty: goal position hierarchy, start position hierarchy, and number of solution paths available. The relative contributions of each of the characteristics strongly depended on which performance factor defined performance. We conclude that TOL problem performance is multifaceted, and that classifying problem difficulty using only the minimum moves necessary to solve the problem is inadequate.     

Form follows function: Learning about function helps children learn about shape

Object functions help young children to organize new artifact categories. However, the scope of their influence is unknown. We explore whether functions highlight property dimensions that are relevant to artifact categories in general. Specifically, using a longitudinal training procedure, we assessed whether experience with functions highlights shape as important for categorization. Seventeen-month-olds were provided experience with novel categories of similarly shaped objects. In Study 1, the function group learned about the objects’ shape-based functions; a control group did not. In Study 2, 17-month-olds were trained on the same categories, but the objects’ shapes and functions were no longer causally related. Only the function group in Study 1 subsequently used shape reliably when categorizing novel objects. These results suggest that function is instrumental in establishing a ‘shape bias’ in early categorization and that it does so via conceptually based processes.     

孤独症的认知障碍研究及其评述

执行功能紊乱理论(Theory of Executive Dysfunction)、弱的中央统合理论(Weak Central Coherence theory)和心理理论假说(The Theory of Mind Hypothesis)是解释孤独症认知障碍的三种重要理论。本文着重通过回顾以往的实验研究来探讨三种理论的产生、发展及前进的方向, 以及三大理论之间的关系。三者可能从不同侧面诠释了孤独症认知障碍的机制, 如何综合起来更好地揭示孤独症的认知障碍和病理机制, 尚需深入和全面的研究。同时更多地考虑不同认知因素的交互影响以及研究的生态学效度, 可能是进一步研究需要考虑的问题。     

国外父母-孩子自传叙事研究现状及展望

父母-孩子自传叙事是指父母与孩子共同对过去发生的生活事件进行回忆和交流, 是实现自传记忆社会功能的一种重要形式。父母-孩子自传叙事的社会功能有教育和指导孩子、保持亲子亲密性等作用。在父母-孩子自传叙事的风格、结构和内容三个层面, 父母-孩子自传叙事对儿童认知发展、社会情感发展、自传记忆表征等方面有重要影响; 另外, 父母-孩子自传叙事中还存在有性别和社会、文化差异。未来的研究应注意线索词材料的类型以及与儿童心理理论发展、社会层次、纵向研究设计的结合。     

一种测量记忆监测相对准确性的新指标：da

记忆监测的相对准确性是元记忆研究中一个重要内容。研究者采用了各种方法来测量人们记忆监测的判断值对正确项目和错误项目的区分度,例如相关法、信号检测论(SDT)测量法。其中,gamma相关从1984年起一直被广泛用于记忆监测相对准确性的测量。基于SDT的新指标da弥补了gamma相关在实际应用中的不足,并引发了新的研究兴趣。文章对da的提出背景、计算方法和应用前景进行了详细的介绍,对da与其他常用方法在使用中的优势进行了比较。对da的具体应用进行了说明,同时指出了da的使用条件。     

大学生家庭功能、心理弹性与自我分化的关系

研究了378名大学生心理弹性在家庭功能与自我分化关系中的中介作用。结果:(1)家庭功能亲密度、适应性与心理弹性、自我分化均呈正相关;(2)心理弹性的情绪控制、家庭支持和人际协助三个因子对自我分化有一定程度的预测作用;(3)层级回归发现,在同时考虑心理弹性各因子的影响时,对自我分化具有显著预测作用的家庭功能亲密度β值下降且显著性水平降低。结论:心理弹性的情绪控制、家庭支持和人际协助三个因子在家庭功能亲密度与自我分化的关系中具有部分中介作用。