Intellectual and adaptive functioning in Sturge-Weber Syndrome

The present study examined the intellectual and adaptive functioning in a sample of children and young adults with Sturge-Weber Syndrome (SWS). A total of 80 research participants from a SWS study database underwent full neurological evaluation as part of their participation or concurrent medical care. Twenty-nine of the participants received neuropsychological evaluations. Analyses indicated no significant demographic or neurological differences between those who did and did not receive neuropsychological evaluations. Overall, the neuropsychological evaluation sample displayed significantly lower functioning relative to published normative data across domains of intellectual and adaptive functioning. Thirty-two percent of the sample displayed impaired performance (standard score ≤ 75) in intellectual functioning and 58% displayed impaired performance in adaptive functioning. Hemiparesis status independently predicted overall adaptive functioning while seizure frequency independently predicted overall intellectual functioning. Younger participants displayed significantly higher (more intact) ratings in adaptive functioning compared to older participants, specifically in overall adaptive functioning, motor skills, and community living skills. A composite measure of neurological status (SWS-NRS) incorporating seizure and hemiparesis status effectively distinguished between individuals with impaired or nonimpaired adaptive and intellectual functioning and showed promise as a screening method for identifying individuals with more involved intellectual and/or adaptive needs.     

Cognitive reserve and cognitive function in healthy older people: a meta-analysis

The associations between proxy measures of cognitive reserve (CR) and cognition vary across studies and cognitive domains. This meta-analysis aimed to assess the relationship between CR and cognition in multiple domains (memory, executive function, visuospatial ability, and language). CR was considered in terms of three key proxy measures – educational level, occupational status, and engagement in cognitively stimulating activities – individually and in combination. One-hundred and thirty-five studies representing 128,328 participants were included. Of these, 109 used a measure of education, 19 used a measure of occupation, 31 used a measure of participation in cognitively stimulating activities, and 6 used a combination of these. All three proxy measures had a modest positive association with cognition; occupational status and cognitive activities showed the most variation across cognitive domains. This supports the view that the commonly used proxy measures of CR share an underlying process but that each additionally provides a unique contribution to CR.     

组织中的人际冲突:类型、模型与表达

组织中的人际冲突是组织成员在分歧、负面情绪与干扰的相互作用下,通过意义建构导致互动双方在认知、情感与行为方面产生的一系列反应过程。现有研究将组织中的人际冲突分为单特征型和多特征型,集中探讨作用模型,并基于表达层面解析冲突的维度和作用模式。本文尝试将冲突类型、表达方式以及作用模型进行嵌入式整合,提出组织中人际冲突的具体应对策略。未来研究可将认知差异嵌入过程框架,探求冲突显现的临界点,验证应对方式的有效性,探究组织权力的影响,开展基于多元亚文化下组织中人际冲突的本土化研究。     

Tool use in left brain damage and Alzheimer's disease: What about function and manipulation knowledge?

Tool use disorders are usually associated with difficulties in retrieving function and manipulation knowledge. Here, we investigate tool use (Real Tool Use, RTU), function (Functional Association, FA) and manipulation knowledge (Gesture Recognition, GR) in 17 left‐brain‐damaged (LBD) patients and 14 AD patients (Alzheimer disease). LBD group exhibited predicted deficit on RTU but not on FA and GR while AD patients showed deficits on GR and FA with preserved tool use skills. These findings question the role played by function and manipulation knowledge in actual tool use.     

Differential effects of assisted cycling therapy on short-term and working memory of adolescents with Down syndrome

Persons with Down syndrome (DS) suffer from prefrontal cortex dysfunction and deficits in executive functions. The current study examined the effects assisted cycling therapy (ACT) on short-term (STM) and working memory (WM) in adolescents with DS. During ACT, the cadence of participants on a stationary bicycle was augmented with an electrical motor to 180% of the voluntary cadence. Participants completed eight weeks of ACT (n?=?17), eight weeks of voluntary cycling (VC) at their own preferred cadence (n?=?16), or eight weeks of no cycling (np?≥?.149) and working memory improved only in the ACT group (Hedge’s g?=?1.66; p?=?.003). The results indicate that assisted high-cadence cycling (i.e. ACT) produces superior neural benefits in the dorsolateral prefrontal cortex compared to VC.     

初中生函数概念发展的特点

本研究通过测验法对北京市六所中学的８０２名初一至初三的学生进行考察,研究了初中生函数要领的发展水平及其特点,结果表明,初中三个年级学生函数要领的发展,从总体上看,随着看级的增高呈上升的发展趋势,但年级结学生函数概念发展的影响不显著,制约 初中学生函数的概念发展水平的关键是,学生所受教育的质量,学生主要以接受教育的方式来获得函数概念。     

心理行为干预对乳腺癌患者情绪反应及免疫功能的影响

按随机和匹配原则,将40名乳腺癌放疗患者分入干预组和对照组。对干预组患者进行为期4周的心理行为干预,对照组仅接受相应的医药治疗。以肿瘤病人情绪适应问卷(MAC)和免疫测试法研究患者干预前后的情绪反应和免疫功能,探讨心理行为干预对乳腺癌患者情绪反应和免疫功能的影响。结果发现,心理行为干预有利于提高患者NK细胞活性(NKCA);并有助于维持放疗期间患者的白细胞水平。     

神经元活动的时相同步与脑功能整合

从大脑整合的角度分析心理的神经机制。神经元之间的交互和动态联结而构成神经集合被认为是每一个认知活动的基础。然而这一交互作用的具体性质,即脑整合的机制尚未明确。通过对有关实验结果的分析,认为神经元活动的时相同步可能是脑整合的机制。     

The influence of workplace discrimination and vigilance on job satisfaction with people who stutter

Purpose The purpose of the present study is to examine the association between workplace discrimination, vigilance, and job satisfaction in people who stutter and compare this with people who do not stutter. Method Seventy-two people who stutter (PWS) and 92 people who do not stutter (PWNS) participated in an online survey. Participants completed a survey assessing 6 different areas: (a) background information, (b) job satisfaction, (c) everyday discrimination, and (d) heightened vigilance. Mediation analyses were conducted to evaluate the relationship between the independent variables and dependent variable. Results There was a relationship between being a PWS and job satisfaction, discrimination, and vigilance. PWS were found to experience higher discrimination as well as be more vigilant. Discrimination and vigilance were found to mediate the relationship between stuttering and job satisfaction. Conclusion Results of this study indicate that the participants who stutter differ from PWNS in their job satisfaction, discrimination, and vigilance. Clinicians can prepare PWS with self-advocacy strategies, legal knowledge of what their rights are as an employee who identifies as a person who stutters with a disability, a legal understanding of workplace discrimination, and counseling on the impact of vigilance on workplace experiences.