Developmental stuttering and the role of the supplementary motor cortex

Developmental stuttering is a frequent neurodevelopmental disorder with a complex neurobiological basis. Robust neural markers of stuttering include imbalanced activity of speech and motor related brain regions, and their impaired structural connectivity. The dynamic interaction of cortical regions is regulated by the cortico-basal ganglia-thalamo-cortical system with the supplementary motor area constituting a crucial cortical site. The SMA integrates information from different neural circuits, and manages information about motor programs such as self-initiated movements, motor sequences, and motor learning. Abnormal functioning of SMA is increasingly reported in stuttering, and has been recently indicated as an additional “neural marker” of DS: anatomical and functional data have documented abnormal structure and activity of the SMA, especially in motor and speech networks. Its connectivity is often impaired, especially when considering networks of the left hemisphere. Compatibly, recent data suggest that, in DS, SMA is part of a poorly synchronized neural network, thus resulting in a likely substrate for the appearance of DS symptoms. However, as evident when considering neural models of stuttering, the role of SMA has not been fully clarified. Herein, the available evidence is reviewed, which highlights the role of the SMA in DS as a neural “hub”, receiving and conveying altered information, thus “gating” the release of correct or abnormal motor plans.     

学习困难青少年认知控制特点研究

本研究基于双重认知控制理论,通过比较学困组和对照组在持续性操作任务上的表现来探究学习困难青少年的认知控制特点。结果发现：（1）在反应性控制的指标上,学困组和对照组的反应时和正确率不存在显著差异,但学困组对探测刺激的辨别力指数更低,显示学困组的反应性控制能力存在一定不足;（2）在主动性控制的指标上,学困组的反应时更长、正确率更低,且对线索刺激的辨别力指数更低,显示学困组在对线索刺激保持的各项指标上都比对照组更差,说明学困组在主动性控制上的缺陷更为明显。     

It is time for a general comment on children’s spiritual development

Reviewing the general comments by the Committee on the Rights of the Child (CRC) and the state reports to the CRC reveal a mixed picture. How could a general comment by CRC on the right to spiritual development assist states in their policies and programmes? First, current understandings of spiritual well-being – one’s relationship to oneself, others, nature and the transcendent – encompass all relevant dimensions of meaning-making, enhanced awareness and connectedness. Second, the CRC has elaborated on spiritual development in 16 of its 21 general comments, providing sources from which a comprehensive elaboration can be done. Third, the understanding of the term spiritual is diverse among states. Fourth, a general comment will clarify the term spiritual development and inspire and guide relevant policies and programmes.     

The tendency to overestimate what is visible in a planar mirror amongst adults and children

Adults hold several mistaken beliefs about simple mechanical and optical phenomena. In particular, many adults believe that they would be able to see their own image in a mirror before they are in front of it. Similarly, they expect objects to become visible in mirrors before they actually do. This overestimation of what is visible is known as the early error (Bertamini, Spooner, & Hecht, 2003). It has been suggested that incorrect models about mechanics, and therefore erroneous beliefs, develop over time, as evidenced by good performance in young children (Kaiser, McCloskey, & Proffitt, 1986). With respect to knowledge about what is visible in mirrors we report the first developmental data. We confirmed an effect for prospective University students but found no evidence of any early error in children between the age of 5 and 11. This erroneous belief about mirrors develops during the later school years when people develop a system of beliefs based on experience.     

Speech prosody and developmental dyslexia: Reduced phonological awareness in the context of intact phonological representations

Recent research indicates that awareness of the rhythmic patterns present in spoken language (i.e., prosody) may be an important and relatively overlooked predictor of reading ability. Two studies investigated the prosodic processing abilities of skilled adult readers and adults with developmental dyslexia. Participants with dyslexia showed reduced awareness of lexical and metrical stress and these skills were found to be significantly associated with, and predictive of, phonological decoding ability. In contrast, the same individuals showed normal patterns of stress based priming at magnitudes similar to controls. These results—suggesting reduced phonological awareness in the context of intact phonological representations—are consistent with recent findings reported in the domain of phonemic processing. Implications for the phonological deficit theory of dyslexia are discussed.     

Effects of reinforcer choice measured in single-operant and concurrent-schedule procedures

The effects of choice and no choice of reinforcer on the response rates of 3 children with autism were compared across single-operant and concurrent-schedule procedures. No consistent differences in responding between choice and no-choice components emerged during single-operant phases. During the concurrent-schedule phases, however, all participants had substantially higher rates of responding to the button that led to a choice among reinforcers than to the button that did not lead to choice.     

Effects of deprivation on engagement in preferred activities by persons with developmental disabilities

This study examined the effects of deprivation on engagement in activities for 3 adult men with developmental disabilities. First, an assessment was conducted to identify a high- and a low-preference activity for each participant. Second, the high-preference activity was made available following three amounts of deprivation of the activity (15 min, 2 hr, and 1 to 4 days); the low-preference activity was made available following the schedule of deprivation that produced the highest level of engagement by each participant in the high-preference activity. The results were that 1 to 4 days of deprivation produced the highest average amounts of engagement in the high-preference activity for each participant; this amount of deprivation did not produce high engagement in the low-preference activities. Third, the deprivation procedures and results were replicated when high-preference activities were presented by teachers during the participants' daily activities when their engagement had been quite low.     

Does the Conners' Continuous Performance Test Aid in ADHD Diagnosis?

The performance of clinic-referred children aged 6–11 (N = 100) was examined using the Conners' Continuous Performance Test (CPT) and measures of auditory attention (Auditory Continuous Performance Test; ACPT), phonological awareness, visual processing speed, and visual-motor competence. The Conners' CPT overall index was unrelated to measures of visual processing speed or visual-motor competence. Although the Conners' CPT converged with the ACPT, the latter demonstrated age and order effects. Significant variance in Conners' CPT parameters was predicted by phonological awareness measures, suggesting that Reading Disordered (RD) children could be false positives on the Conners' CPT. The Conners' CPT overall index, phonological awareness, and visual-motor measures were submitted to a 2×2 MANCOVA (ADHD vs. RD, covarying for age and socieoeconomic status): a main effect for RD status was found. Children with ADHD did not have higher Conners' CPT scores than did clinical controls; however, children with Reading Disorders did. Phonological measures distinguished RD children from ADHD children and other clinical controls. ADHD children who failed the Conners' CPT were rated by teachers as more hyperactive. Despite the strengths of the Conners' CPT, its utility for differential diagnosis of ADHD is questioned.     

The relation of learning disabilities to the long-term outcomes of concussion

ObjectiveThis study sought to cross-sectionally evaluate the relation between learning disorders (LD) and long-term concussion outcomes.MethodSeventy-three asymptomatic male university athletes (23 history of concussion with LD; 24 history of concussion no LD; 26 controls) completed the Beck Depression Inventory-2 (BDI-II), the Profile of Mood States (POMS), the Cogstate battery, and an Oddball task during which event-related brain potentials were recorded.ResultsConcussed athletes with LD exhibited greater depressive symptoms (BDI-II), greater total mood disturbance (POMS), decreased accuracy on the One-Card Learning and the N-back task (Cogstate), decreased accuracy on the Oddball task, and reduced ERN amplitude relative to both the concussed athletes without a LD and controls. Concussed athletes with LD also exhibited prolonged P3 latency relative to controls. Irrespective of LD, concussed athletes exhibited increased anger-hostility and decreased Pe amplitudes relative to controls. No differences were observed in P3a amplitude or latency.ConclusionHaving LD may be a significant factor moderating the neurophysiological, cognitive and psycho-affective outcomes of concussion, and may explain a significant portion of the persistent deficits observed by researchers and clinicians.     

Inhibition and shifting in children with learning deficits in arithmetic and reading

The executive functions of inhibition and shifting were studied in arithmetic-disabled children, reading-disabled children, reading plus arithmetic-disabled children, and controls (N = 74). Measures involved the rapid naming of objects, digits, letters, or quantities with or without additional task requirements that reflected inhibition or shifting. Also, the Making Trails task, reflecting shifting, was administered. For tasks without executive demands, arithmetic-disabled children were slower in the naming of digits and quantities, whereas reading-disabled children were slower in the naming of digits and letters. For the executive tasks, arithmetic-disabled children as well as reading plus arithmetic-disabled children were impaired on the Making Trails task and on an object naming task that required both inhibition and shifting. Reading-disabled children exhibited no problems in executive functioning. Furthermore, it was shown that reading plus arithmetic-disabled children experienced the combination of problems that characterize children with a single learning deficit.