Is CAG sequence length in the androgen receptor gene correlated with finger-length ratio?

Manning, Bundred, Newton, and Flanagan reported a significant correlation of .29 in a sample of 50 British males between the length of a repeated sequence on the androgen receptor gene and 2D:4D finger-length ratio on the right hand. We report a 2nd failure to replicate this result. Ours was a sample of 182 Australian male twins studied for other purposes, for whom both measures were available. The result was a nonsignificant correlation of −.055. A similar result was obtained for female twins, and for comparisons within sibling pairs. Correlations are also reported for left hands and right-left differences--the last showed a weak tendency toward replication.     

Manual reaction time to linguistic stimuli in child stutterers and nonstutterers

Ten stuttering and ten nonstuttering children, ages 4–8 yr, served as subjects for a motor reaction task to simple and complex linguistic stimuli. The subjects reacted by pressing one of four panels on a touch-sensitive board that depicted the appropriate semantic relationship in response to 30 simple and complex linguistic stimuli. There was a significant increase in the reaction time of both groups with increasing linguistic complexity. No significant differences were found in the reaction time between the two groups, nor in the interaction between group and complexity. Implications regarding linguistic processing are discussed, and an “overload” hypothesis of stuttering is dispelled. It is concluded that stutterers and nonstutterers in this study did not differ in their reaction time nor in their processing time of linguistic material.     

Case report of stuttering acquired in association with phenytoin use for post-head-injury seizures

Previous research indicates that stuttering and deficits in motor performance may be associated with the use of phenytoin (Dilantin). The present report concerns a case of stuttering acquired in association with phenytoin use for post-head-injury seizures. The extent and nature of dysfluencies and the motor performance of speech and nonspeech muscle systems were evaluated over an extended period during which changes in anticonvulsant medication were made. Reductions in dysfluency levels and improved motor performance were observed following a medication change from phenytoin to carbamazepine. Performance on tests assessing nonmotor functions, such as memory and attention, was equivalent before and after the medication change. The apparent association between dysfluency levels, motor performance deficits, and phenytoin suggest that in the present case stuttering resulted in part from a general impairment in motor control.     

Inner speech as a learned skill

Three experiments are reported which address the problem of defining a role for inner speech. Experiments 1 and 2 establish that inner speech is acquired by normally developing readers between the ages of 8 and 11, and that both slow and fast readers show a similar pattern of acquistition, but do so at a different rate from normal readers. We suggest that the development of inner speech accompanies a strategy of reading aloud “with expression”; and that it is a manifestation of the need to prestructure oral utterances. These will thus contain the lexical items visible on the page within an appropriate prosodic envelope. Both segmental and suprasegmental phonemes contribute to meaning of spoken and, by analogy, written language. Experiment 3 showed that children at this critical point in learning to read comprehended text better when certain prosodic features were made visible on the text. Prosodic restructureing may thus be an important skill acquired by young readers as they progress toward fluent, silent adult reading.     

Asymmetrical effects of Pavlovian excitatory and inhibitory aversive transfer on Pavlovian appetitive responding and acquisition

Predictions of a theory of Pavlovian motivational transfer, which incorporates principles of both the theory of reciprocal inhibition and the Rescorla-Wagner model, were tested in several Pavlovian aversive to Pavlovian appetitive transfer tasks. As predicted, the presence of a signal for an aversive event, conditioned stimulus (AV CS+), reliably suppressed performance of appetitive conditioned responses (CRs) whether imposed during acquisition or on independently established responding. Acquisition of appetitive responding to a novel CS reinforced in compound with an AV CS+, however, was enhanced (“superconditioning”). This observation suggests that the effects of a discrepancy between expectation and actual outcome on a conditioning trial are influenced by the affective value of both the expectation and the reinforcer. These transfer effects were not symmetrical for an inhibitory aversive stimulus (AV CS?). An AV CS? did not enhance appetitive responding compared to a random control condition, nor did the AV CS? reduce (i.e., block) appetitive conditioning to a novel CS when appetitive reinforcement occurred in the presence of the AV CS?. Comparison of the two shock-exposed conditions with a naive control condition suggests that previous results that were apparently consistent with inhibitory aversive enhancement and blocking of appetitive conditioning may have been due to aversive context conditioning.     

Cognitive analysis of a case of pure dysgraphia

An Italian patient with a pure dysgraphia who incorrectly spelled words and nonwords is described. The spelling errors made by the patient were not affected by lexical factors (e.g., frequency, form class) and were qualitatively the same for words and nonwords. The pattern of writing performance is discussed in relation to current models of writing and, specifically, in relation to the role of the Output Grapheme Buffer and Phoneme-Grapheme Conversion in writing.     

D型人格对大学新生心理健康的影响:基于三个时间点调查数据的有调节的中介模型

为考察感知到的压力在D型人格与大学新生心理健康关系中的中介作用及心理韧性的调节作用。在新生入学3个月内的不同时间点,利用D型人格量表（T1）、心理韧性量表（T2）、感知到的压力量表（T2）和心理健康量表（T3）对某大学1428名大学新生进行调查。结果显示：（1）在控制性别、年龄、是否恋爱和心理健康（T1）后,社交抑制对感知到的压力具有显著预测作用,感知到的压力对心理健康具有显著预测作用,即社交抑制通过感知到的压力的中介作用间接影响心理健康;在负性情感与心理健康的关系中,感知到的压力中介作用不成立;（2）心理韧性在社交抑制与心理健康的关系中调节效应显著;心理韧性在感知到的压力与心理健康的关系中调节效应显著;（3）一个有调节的中介模型成立。研究结果不仅有助于理解大学新生适应大学生活过程中的心理状况,而且为提高大学新生心理健康水平提供参考依据。     

Focal changes in cerebral blood flow produced by monetary incentive during a mental mathematics task in normal and depressed subjects

The purpose of this experiment was to determine the effect of incentive-induced arousal on the diffuse and regional cerebral blood flow (rCBF) response during cognitive activation for normal and depressed groups. Two normal rest CBF measurements were followed by two mental mathematics activation CBF measurements. For the first activation measurement, half the subjects in each group were offered monetary incentive for correct performance and half the subjects received no monetary incentive. All subjects were offered monetary incentive on the final activation run. The effect of monetary incentive on the first activation run was to increase CBF activation at four detectors in the left hemisphere. Incentive did not affect the CBF activation response when introduced following practice on the activation task (on the final run). Depressed groups had lower resting blood flow than normals, but the distribution of flow and the CBF response to incentive were almost identical in the two groups.     

Interpretation and use of the Luria-Nebraska battery

In a recent article, T. V. Akhutina and L. S. Tsvetkova (1983, Brain and Cognition 2, 129-134) presented an analysis of the Luria-Nebraska Neuropsychological Battery. Along with their generally positive review, they raised questions regarding the importance of the qualitative aspects of patients' performance in the interpretation of the battery. We agree with the authors that any interpretation of the battery which does not consider qualitative performance can limit the power and applicability of the battery. The procedures of item analysis and qualitative analysis are discussed as essential to a comprehensive interpretation of the battery. Also discussed are comments on additional scaling for the battery and the development of a standardized qualitative scoring system.     

The different types of limb apraxia errors made by patients with left vs. right hemisphere damage

Limb apraxia errors were compared among normal controls and right- or left-hemisphere-damaged patients as they imitated gestures with the ipsilateral hand. Both brain-damaged groups made similar errors on nonrepresentative and representative/intransitive movements. In contrast for pretended object use movements (transitive), the left-hemisphere-damaged group made more arm position and classical body-part-as-object errors while the right hemisphere group made as many partial errors and more less-primitive, body-part-as-object errors than the left-hemisphere-damaged group. These results help explain why a certain percentage of right-hemisphere-damaged patients are labeled apraxic, but also suggest that the left hemisphere is more important for integrating intrapersonal space and the “representation” of extrapersonal space.