Microinfusion of the D1 receptor antagonist, SCH23390 into the IL but not the BLA impairs consolidation of extinction of auditory fear conditioning

In auditory fear conditioning, repeated presentation of the tone in the absence of the shock leads to extinction of the acquired fear response. Both the medial prefrontal cortex (mPFC) and the basolateral amygdala (BLA) are involved in extinction. Here we examined this involvement by antagonizing D1 receptors in both regions, in the rat. We microinfused the D1 receptor antagonist, SCH23390, into the infra-limbic part of the mPFC (IL) or BLA at different time points. SCH23390 mircoinfused into the IL either before extinction acquisition or following short extinction training resulted in impairment of extinction consolidation. Microinfusion of SCH23390 into the BLA, prior to acquisition of extinction caused impairment in acquisition of extinction without affecting extinction consolidation. This is supported by the results showing that microinfusion of SCH23390 into the BLA following a short-training session did not affect consolidation. These results further strengthen the role of mPFC in consolidation of extinction while highlighting the role of the D1 receptors in this process.     

3D feedback and observation for motor learning: Application to the roundoff movement in gymnastics

In this paper, we assessed the efficacy of different types of visual information for improving the execution of the roundoff movement in gymnastics. Specifically, two types of 3D feedback were compared to a 3D visualization only displaying the movement of the expert (observation) as well as to a more ‘traditional’ video observation. The improvement in movement execution was measured using different methods, namely subjective evaluations performed by official judges, and more ’quantitative appraisals based on time series analyses. Video demonstration providing information about the expert and 3D feedback (i.e., using 3D representation of the movement in monoscopic vision) combining information about the movement of the expert and the movement of the learner were the two types of feedback giving rise to the best improvement of movement execution, as subjectively evaluated by judges. Much less conclusive results were obtained when assessing movement execution using quantification methods based on time series analysis. Correlation analyses showed that the subjective evaluation performed by the judges can hardly be predicted/ explained by the ‘more objective’ results of time series analyses.     

Empathizing, systemizing and finger length ratio in a Swedish sample

von Horn, A., Bäckman, L., Davidsson, T. & Hansen, S. (2010). Empathizing, systemizing and finger length ratio in a Swedish sample. Scandinavian Journal of Psychology, 51, 31–37.
The Empathy- and Systemizing Quotients (EQ and SQ, respectively; Baron-Cohen, 2003 ) were determined in a Swedish sample consisting mainly of university undergraduates. Females had significantly higher EQ than males, who in turn scored higher on the SQ inventory. Gender explained 12–14% of the variation. Males were strikingly overrepresented in the group defined by a high SQ/low EQ profile or by a large SQ – EQ difference; females dominated among people with a low SQ/high EQ profile or by a large EQ – SQ difference. Students majoring in the natural sciences had higher SQs than psychology majors, but in both groups the gender difference in SQ and EQ was strong. For each participant a weighted composite score was generated by multivariate processing of the EQ and SQ data (Partial Least Square Discriminant Analysis). These scores were associated in a sex-linked fashion to a biometric measure reflecting prenatal testosterone exposure, i.e. the ratio between index (2D)- and ring (4D) finger lengths. In males a high (female-typical) 2D:4D ratio predicted an enhanced tendency to empathize and a reduced tendency to systemize; in women, by contrast, the 2D:4D ratio was unrelated to these traits. The present research confirms earlier work of a gender difference in EQ and SQ. The difference appears robust as it appears as large in Sweden (a country with high cultural gender-equality) as in countries with considerably lower gender-equality.     

多巴胺D2受体参与调节感觉门控的机制

精神分裂症是一种常见的病因不明的精神疾病。大量文献表明精神分裂症患者所表现出来的认知紊乱和思维异常等症状与感觉门控功能的缺失有密切的关系, 感觉门控是指在充满刺激的环境中, 从外界的感觉信息中过滤无关的感觉信息然后执行与注意力相关的认知过程, 以对显著的刺激做出反应。研究感觉门控的经典范式是震惊反射的前脉冲抑制。研究发现多巴胺D₂受体可以参与调控前脉冲抑制的过程, 但是多巴胺D₂受体参与调控前脉冲抑制的机制仍不清楚。探讨多巴胺D₂受体参与调控感觉门控即前脉冲抑制的关键脑区、神经环路及分子机制, 有利于促进对精神分裂症感觉门控功能的深入研究。     

D型人格对大学新生心理健康的影响:基于三个时间点调查数据的有调节的中介模型

为考察感知到的压力在D型人格与大学新生心理健康关系中的中介作用及心理韧性的调节作用。在新生入学3个月内的不同时间点,利用D型人格量表（T1）、心理韧性量表（T2）、感知到的压力量表（T2）和心理健康量表（T3）对某大学1428名大学新生进行调查。结果显示：（1）在控制性别、年龄、是否恋爱和心理健康（T1）后,社交抑制对感知到的压力具有显著预测作用,感知到的压力对心理健康具有显著预测作用,即社交抑制通过感知到的压力的中介作用间接影响心理健康;在负性情感与心理健康的关系中,感知到的压力中介作用不成立;（2）心理韧性在社交抑制与心理健康的关系中调节效应显著;心理韧性在感知到的压力与心理健康的关系中调节效应显著;（3）一个有调节的中介模型成立。研究结果不仅有助于理解大学新生适应大学生活过程中的心理状况,而且为提高大学新生心理健康水平提供参考依据。     

Improving payment of traffic fines with financial incentives: Discounts vs. penalties

The effective enforcement of traffic laws is critical for improved road safety outcomes. Decisions to follow traffic rules and pay fines are influenced by formal institutions (e.g. laws, court summons, and fines) as well as informal institutions (e.g. norms and aspects of culture). Formal and informal institutions create incentives that should be designed to steer individuals’ behaviour towards desired outcomes. Unfortunately, there is no reason to believe that the institutions to deal with traffic violations in South Africa currently create effective incentives. This paper discusses the findings of a controlled laboratory experiment, conducted with a sample of university students, that tested the efficacy of different financial incentives that may influence the payment of traffic fines. An early payment discount was compared to a late payment penalty (used in other countries, for example, some states in the USA), and to the absence of any incentives. Furthermore, we examined whether the willingness to settle fines is sensitive to the likelihood of detection by the authorities. We found that introducing financial incentives significantly increases voluntary payment of fines, irrespective of whether immediate payment is encouraged with a discount or late payment is discouraged with a surcharge. In addition, subjects are more sensitive to the likelihood of detection when financial incentives are present.     

Asymmetrical effects of Pavlovian excitatory and inhibitory aversive transfer on Pavlovian appetitive responding and acquisition

Predictions of a theory of Pavlovian motivational transfer, which incorporates principles of both the theory of reciprocal inhibition and the Rescorla-Wagner model, were tested in several Pavlovian aversive to Pavlovian appetitive transfer tasks. As predicted, the presence of a signal for an aversive event, conditioned stimulus (AV CS+), reliably suppressed performance of appetitive conditioned responses (CRs) whether imposed during acquisition or on independently established responding. Acquisition of appetitive responding to a novel CS reinforced in compound with an AV CS+, however, was enhanced (“superconditioning”). This observation suggests that the effects of a discrepancy between expectation and actual outcome on a conditioning trial are influenced by the affective value of both the expectation and the reinforcer. These transfer effects were not symmetrical for an inhibitory aversive stimulus (AV CS?). An AV CS? did not enhance appetitive responding compared to a random control condition, nor did the AV CS? reduce (i.e., block) appetitive conditioning to a novel CS when appetitive reinforcement occurred in the presence of the AV CS?. Comparison of the two shock-exposed conditions with a naive control condition suggests that previous results that were apparently consistent with inhibitory aversive enhancement and blocking of appetitive conditioning may have been due to aversive context conditioning.     

Manual reaction time to linguistic stimuli in child stutterers and nonstutterers

Ten stuttering and ten nonstuttering children, ages 4–8 yr, served as subjects for a motor reaction task to simple and complex linguistic stimuli. The subjects reacted by pressing one of four panels on a touch-sensitive board that depicted the appropriate semantic relationship in response to 30 simple and complex linguistic stimuli. There was a significant increase in the reaction time of both groups with increasing linguistic complexity. No significant differences were found in the reaction time between the two groups, nor in the interaction between group and complexity. Implications regarding linguistic processing are discussed, and an “overload” hypothesis of stuttering is dispelled. It is concluded that stutterers and nonstutterers in this study did not differ in their reaction time nor in their processing time of linguistic material.