冠心病患者微量白蛋白尿与C反应蛋白的关系

研究冠心病患者微量白蛋白尿与血清C反应蛋白(CRP)相关性.研究对象为接受冠状动脉造影确诊为冠心病的住院患者87例,检测其尿白蛋白/肌酐浓度值(ACR)、血清C反应蛋白水平及其他指标,并与35例冠状动脉造影为非冠心病的患者进行比较.冠心病组lgACR及lgCRP水平明显高于正常对照组(P＜0.05).lgACR与lgCRP呈正相关(r=0.275,P=0.005),且均为冠心病的独立预测因素.冠心病患者微量白蛋白尿与血清C反应蛋白均明显增加.ACR、CRP均为冠心病的独立预测因素.在微量白蛋白尿的发生过程中可能有低度炎症(CRP)的参与.     

从库恩历史主义看心力衰竭发病机制的研究历程

本文从古希腊Hippocrates的描述作为回顾起点,阐述对心衰发病机制认识过程的六次演变;分析其中的学术背景、重要事件和人物的历史贡献,并从库恩历史主义视角进行深入的哲学思考,有助于总结蕴涵在这一历史进程的经验和规律,有利于培养科学方法论、启迪和开拓科研思路。     

呼吸机依赖患者撤机失败原因及对策

机械通气是近年来抢救呼吸衰竭患者的重要生命支持手段,但使用呼吸机的时间超过2周可导致撤机困难。本文详细分析了诸如心理障碍、营养不良、心肺功能不全以及撤机方法不当等各种可导致困难撤机的原因,并针对各个原因提出相应的治疗及护理对策,从而降低临床上困难撤机的发生率。     

Adolescents' evaluative beliefs of failure: explorations in a Chinese Singaporean sample

Our study explored evaluative beliefs of failure to see whether positive and negative beliefs of failure are bivariate in nature within three domains of an adolescent's life (academic, social, and athletic) and how such beliefs are differentially linked to the importance of a domain, the frequency of failure in a domain, and the extremity of negative emotions experienced when encountering failure in a domain. A total of 163 Chinese Singaporean students in Secondary 3 and 4 (Grades 9 and 10) from two Singapore schools participated in the study by completing a questionnaire. Results from various analyses converged to demonstrate that evaluative beliefs could be distinguished by both valence (positive and negative) and domain (academic, social, and athletic). The six evaluative beliefs were also distinguished from failure attributions. While there was consensus in what constituted negative beliefs of failure across domains, positive beliefs of failure showed some domain specificity, with unique aspects in particular domains (e.g., the inevitability of failure only in the academic domain). Positive and negative beliefs in the different domains were correlated among themselves, but positive and negative beliefs were uncorrelated within (except for academic) and across domains. Positive and negative beliefs were also differentially linked to domain importance, failure frequency, and extremity of negative emotion. Unexpectedly, domain importance was not linked to negative beliefs but was linked to positive beliefs, while positive and negative beliefs showed domain-specific links with failure frequency. As expected, however, negative beliefs were (positively) linked to extremity of negative emotions while positive beliefs were not linked to such extremity. The conceptual, substantive, and practical implications of these results are discussed.     

Nascent body ego: Metapsychological and neurophysiological aspects

For Freud, body ego was the organizing basis of the structural theory. He defi ned it as a psychic projection of the body surface. Isakower's and Lewin's classical fi ndings suggest that the body surface experiences of nursing provide the infant with sensory-affective stimulation that initiates a projection of sensory processes towards the psychic realm. During nursing, somato-sensory, gustatory and olfactory modalities merge with a primitive somatic affect of satiation, whereas auditory modality is involved more indirectly and visual contact more gradually. Repeated regularly, such nascent experiences are likely to play a part in the organization of the primitive protosymbolic mental experience. In support of this hypothesis, the authors review fi ndings from a neurophysiological study of infants before, during and after nursing. Nursing is associated with a signifi cant amplitude change in the newborn electroencephalogram (EEG), which wanes before the age of 3 months, and is transformed at the age of 6 months into rhythmic 3-5 Hz hedonic θ-activity. Sucking requires active physiological work, which is shown in a regular rise in heart rate. The hypothesis of a sensory-affective organization of the nascent body ego, enhanced by nursing and active sucking, seems concordant with neurophysiological phenomena related to nursing.     

论复卦的"贵生"思想及其现实意义

复卦是《周易》的十二消息卦之一,约天时为农历十一月冬至日,阳光直射点开始向北半球回归;约卦象呈“雷在地中”欲震、阳刚复长之象:“阳复、阳来”,有一阳来复,万象更新之意,故复卦的卦德为阳为生。关于复归何处的问题,历来是见仁见智,不一而足。本文拟从“复见天地之心”着眼,对复卦的“贵生”思想及其现实意义试作阐发。     

Caregiver Social Problem Solving Abilities and Family Member Adjustment Following Congestive Heart Failure

Family members have a considerable impact on the health and well-being of others in the family. The characteristics of family caregivers that relate to care recipients' positive and negative outcomes associated with chronic disease have received scant empirical attention. We reasoned that family caregiver social problem solving abilities would be associated with depression and life satisfaction reported by persons with congestive heart failure (CHF). Correlational analyses found that caregiver negative orientation toward solving problems was significantly predictive of higher depression and with decreased life satisfaction of persons with CHF. These findings indicate that family caregiver problem solving abilities are important factors in adjustment following CHF. Implications for clinical interventions and theoretical models of problem solving are discussed.     

The role of lay beliefs about group transgressions in acceptance of responsibility for ingroup harm-doing

Denial of responsibility by perpetrator groups is the most common response to group-based transgressions. Refusal to acknowledge responsibility has dire consequences for intergroup relations. In this research we assessed whether shifting lay beliefs about group-based transgressions in general influences acceptance of responsibility for a specific ingroup transgression. In two experimental studies we manipulated lay beliefs about group transgressions as reflecting either a group's stable character (i.e., a global defect construal) or a specific characteristic (i.e., a specific defect construal). Specific defect construals (compared to global defect construals) increased acceptance of ingroup responsibility by increasing group malleability beliefs, but reduced acceptance of ingroup responsibility by reducing the ingroup's perceived moral failure. These effects were moderated by ingroup superiority in Study 1, but not Study 2. We draw implications for our understanding of mechanisms of denial of responsibility, identity threat, and coping with this threat.     

9～11岁儿童对失败学习情景的情绪反应和情绪表达研究

本研究对180名9-11岁儿童在失败学习情景下的情绪反应和情绪表达进行了研究。结果表明：(1)儿童在失败学习情景中情绪表达的意愿受年龄影响。(2)儿童在失败学习情景中的情绪表达原因受年龄和观众背景影响。儿童隐藏情绪的原因主要是害怕消极的后果,表达情绪的原因是为了得到积极的结果。(3)儿童在失败学习情景中情绪表达和隐藏的策略受年龄、性别和观众背景的影响。(4)儿童的后继行为受年龄的影响。     

Fear of Failure Biases Affective and Attentional Responses to Lexical and Pictorial Stimuli

The purpose of this investigation was to examine whether attentional biases would be noticed among individuals differing in levels of fear of failure (FF) as they viewed pictorial and lexical stimuli depicting various affective content. Indices of natural selective attention, namely, viewing time and self-reported affect, were assessed in 137 college students during free viewing picture and word presentation conditions. As hypothesized, FF was (a) negatively associated with self-reported dominance and valence for failure- and unpleasant-themed stimuli, and (b) positively associated with arousal ratings for unpleasant pictures. Although initially suppressed by neuroticism, partial correlation coefficients revealed a significant positive relationship between FF and viewing time for failure pictures. Results are discussed in the context of current theories of emotional reactivity and attentional biases pertaining to the nature of FF. Recommendations are provided for future research to elaborate the mechanisms involved in detrimental effects of FF.