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A 52-year-old man with atypical cerebral dominance (left-handed for writing but mixed handedness for other tasks) suffered an extensive right hemisphere stroke, resulting in a combination of deficits that has not been previously reported. There were profound visual constructive and visual perceptual disturbances and a spatial agraphia, which were consistent with a nondominant hemisphere lesion. There was also a severe apraxic agraphia, which is typically associated with a dominant hemisphere lesion, but no other signs of dominant hemisphere dysfunction such as linguistic disturbance or limb-motor apraxia were present. This case serves to highlight the functional and anatomical relationship between handwriting and other forms of praxis; the various sources of error in letter formation; the need to be specific in labeling and describing agraphias ; and the role of a detailed analysis of writing errors in delineating the neuropsychological processes involved in handwriting.  相似文献   
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This study explored the ability of young children (5 and 8 years old) to make presuppositional inferences to a speaker's belief in uttering a sentence. Presuppositional information is the information a speaker believes to be common between himself and the hearer. The information is cued by a speaker either logically, by the use of specific lexical items, or pragmatically, by the use of an utterance in violation of conventional rules of conversation. Comprehension of the information may require a reading of the context of utterance. Kindergarten and thirdgrade children and adults were read paragraphs containing both logical and pragmatic presuppositional information, as well as a sentence that could be treated in a logical or a pragmatic manner depending on the context of utterance. The results showed that both groups of children and the adults could make presuppositional inferences to a speaker's belief, and that the responses of the children and adults were context sensitive.  相似文献   
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