Feedback during exposure to inescapable shocks and subsequent shock-escape performance

In two experiments, we assessed the ability of a feedback stimulus during helplessness training to reduce the performance deficits common to inescapable shock. In each experiment, four groups of rats were exposed to either escapable shock (E), inescapable shock with a feedback stimulus following shock termination (Y-FS), inescapable shock with no feedback stimulus (Y-NFS), or no shock (N). The feedback stimulus eliminated the interference effects of inescapable shock when tested with an FR-3 lever press escape task (Experiment 1) or on an FR-1 task with a 3-s delay between the response and shock termination (Experiment 2). These results suggest that stress-induced biochemical changes may mediate the interference effects seen in inescapably shocked rats.     

Arousal and T-maze choice behavior in mice: A convergent paradigm for neophobia constructs and optimal arousal theory

Three experiments investigating the effects of arousal on the T-maze choice behavior of inbred mouse strains are reported. In Experiment 1, CBA and NZB mice were administered unrewarded free choice alternation tests on 10 consecutive days under either No Shock, Shock Start (shocked in the start box), or Shock Choice (shocked at the choice point) treatment conditions. Both strain and treatment effects were observed: In the No-Shock condition, the nonreactive CBA strain alternated, but the reactive NZB strain did not. In the Shock Start condition the CBA strain showed only a suppressed alternation, while the NZB strain administered the same treatment perseverated. Both strains perseverated in the Shock Choice condition. In Experiment 2, NZB mice administered identical shocks in the start box and goal arms on both trials of five consecutive tests conducted once a day perseverated to the same goal arm in which they had been shocked on the first trial. In Experiment 3, NZB mice punished for perseverating (with shock continuation) and simultaneously reinforced for alternating (with shock termination) showed a “punishment paradox”; they perseverated despite the reinforcement contingencies. These results, which are congruent with the optimal arousal theory and several characteristics the theory shares with the emergent neophobia construct, support the contention that arousal mediates a symmetrical relationship between approach and avoidance along a novelty-familiarity continuum.     

Investigations of the reinstatement of extinguished fear

In two experiments, fear was conditioned to the situational cues in one compartment of a hurdle-jumping apparatus and was then extinguished. Subsequently, either one shock (Experiment 1) or three or nine shocks (Experiment 2) were given in a situation distinctively different from that in which conditioning and extinction had taken place. Although some associative strength between the situational cues and fear was shown to have remained after extinction, in neither experiment did the postextinction-shock treatment increase the fear elicited by these cues: Escape-from-fear performance was no better in the shocked groups than in control groups given no additional shock. Thus, the nonassociative hypothesis which postulates that inflating the value of the representation of the UCS with shock-alone presentations can reinstate the extinguished fear of a stimulus was not supported. Rather, the results showed that, after extinction, an increase in fear of a simulus depended on further conditioning to that stimulus. The data also indicated that the nonvisual components of the situational cues predominated over the visual component.     

Variations in explicitly unpaired training are differentially effective in producing conditioned inhibition

To evaluate a contingency interpretation of conditioned inhibition (CI), rats were given “explicity unpaired” training in which the locus and duration of a CS within the inter-US (shock) interval were systematically manipulated for different groups. Summation and retardation tests in Experiment 1 indicated that stronger CI resulted from both a backward and a trace CS than from a midlocus CS of equal or greater duration. Complementing these findings, the same tests in Experiment 2 showed that, by comparison with novel-stimulus controls, CI developed to a trace CS but not to a mid-locus CS, nor to a trace CS that was accompanied by an immediate signal for the US. These findings argue against a contingency interpretation of CI and favor a contiguity interpretation stressing the short-term rehearsal of stimulus events. Such rehearsal of the US allows a backward CS, but not a mid-locus CS with an extended US-CS interval, to be discriminated as a signal for nonreinforcement, and thus to develop as a conditioned inhibitor. Similarly, excitatory conditioning to the memory trace of a CS allows the nominal trace CS to develop as a signal for nonreinforcement, and thus as a conditioned inhibitor, but not when its memory trace is overshadowed by another CS that immediately precedes the US. In short, the development of CI is facilitated when excitation is mediated by the memorial processing of either the US or a discrete CS for the US rather than by contextual cues.     

Why using “consciousness” in psychotherapy? Insight,metacognition and self-consciousness

Since its early development, clinical psychology has questioned the impact of “consciousness” on the determination of human responsibility across psychiatric disorders. In recent years, specific clinical approaches have focused on “consciousness” work that could play a key role in psychotherapy. We focused our research on clinical psychology's consciousness-related concepts of insight, self-consciousness, and metacognition. Insight and metacognition, for example, have prompted increased interest in schizophrenia (SZ), bipolar disorder (BD), and, more recently, borderline personality disorder (BPD) treatments as representative of the latest advances in the cognitive and behavioral therapy field. Here we review cognitive, social, and clinical psychology research measuring “consciousness” in BPD, SZ, and BD, exploring the implications of different conceptualizations of consciousness-like concepts for treatment adherence, symptom evolution, and related aspects of psychotherapy. Our results show the overall relevance of using measures of clinical and cognitive insight, emphasizing the more central role of cognitive insight and metacognition in psychotherapy, as it appears that consciousness can remain useful if understood as a cognitive skill. The inclusion of a conceptualization of self-consciousness is important in order to address the social component of psychotherapy, as it does in biopsychosocial approaches. We discuss the implications of such results for global efficacy, for the relevance of the “consciousness” concept to clinical psychology, and for the potential need to keep operationalizing different conceptualizations of it in psychotherapy. We open the debate on the definition of consciousness to motivational aspects of change and to general considerations of both legal and ethical aspects.     

Epistemic cultural constraints on the uses of psychology

This paper describes some epistemic cultural considerations which shape the uses of psychology. I argue the study of mind is bound by the metaphysical background of the given locale and era in which it is practiced. The epistemic setting in which psychology takes place will shape what is worth observing, how it is to be studied, how the data is to be interpreted, and the nature of the ultimate explanatory units. To demonstrate conceptual epistemic constraints, I discuss metaphor use in psychology. In addition, epistemic constraints shape the praxes that arise from structural study of the mind. In order to illustrate this cultural constraint, I discuss Soviet Psychology and provide a contrast between practical uses of psychoanalysis in India, Egypt, and rural Ghana. In response to these conceptual and practical epistemic limitations, psychology could adapt methods drawn from history and anthropology.     

Character-Principlism and the Particularity Objection

This paper is a response to particularist critics of the normative force of moral principles. The particularist critique, as I understand it, is a rejection not only of principle-based accounts of moral deliberation and justification, but also of accounts of character in which principles play a central role. I focus on the latter challenge and counter it with a view I call character-principlism .
I begin by discussing in a general way what motivates the particularity objection to principles and then contrast two views – both of which insist on the importance of attentiveness to particularity – about the relative normative status of principles and particular cases. I present some reasons for believing that we need a more normatively robust conception of the role of moral principles than the particularists provide. In the main portion of the paper, I discuss how character-principlism sees principles functioning in our lives and the lives we lead with others. I contrast this with some other accounts of desirable character that particularists can embrace, and argue that these are seriously flawed because, unlike character-principlism, they cannot satisfactorily explain how a person could possess the constancy of character that moral integrity requires.     

临床经验对诊断的双重作用及改造

文中用辩证唯物主义的观点,阐述了临床经验的定义、来源及指导实践过程中的意义,指出其具有促进诊断和引起误诊的双重作用,并用临床病历例子详细说明其双重作用的形式、导致结果及产生的原因。指出临床经验的双重作用在临床工作中的重要性及局限性,提出对经验的改造完善途径,以能充分表现出其促进诊断的作用,而最大限度降低其导致误诊的程度,发挥在临床工作中的良性作用。     

A signal detection framework for the evaluation of probabilistic forecasts

In this paper I formulate an approach for evaluating probabilistic forecasts in terms of signal detection theory. Signal detection theory provides a powerful perspective for this type of problem, and a rich empirical background including methodological tools as well as an extensive body of research in many domains. I propose procedures which emphasize the maximization of expected utility for the decision maker who uses the forecasts. Further, I suggest approaches to obtaining indices of calibration and resolution within this framework. I also present arguments that the proposed indices will exhibit the same basic properties as do decompositions of Brier's (1950, Monthly Weather Review, 78, 1–3) mean probability score. However, the properties may be reflected in different ways, and hence, the present methods may lead to different conclusions about forecasting ability. Finally, I argue that the use of an expected utility loss function makes this approach more appropriate for practical applications as well as for theoretical research than other procedures with more arbitrary loss functions.