抑郁症的脑功能异常:来自静息态功能磁共振成像的证据

静息态功能磁共振成像是指在静息状态下测量的BOLD信号,即受试者安静地躺在扫描仪中,不给受试者任何特定的任务,受试者也不用做任何反应,此时受试者的大脑活动处于自发状态。通过使用该技术可以为抑郁症发作的临床现象提供神经影像学依据,以期为将来抑郁症的治疗提供生物标记。因此,本文综述了大量抑郁症患者在静息态脑功能方面的差异研究,发现了单、双相抑郁症,首、复发抑郁症,早发性、晚发性抑郁症,难治、非难治性抑郁症等不同类型的抑郁症在包括局部一致性(Re Ho)和低频振幅(ALFF)在内的功能分化以及包括功能连接密度(FCD)、功能同伦(VMHC)、复杂网络(Complex Network)和ROI功能连接在内的功能整合两大指标的改变。     

Meta-Analysis of the Effects of Peer-Administered Psychosocial Interventions on Symptoms of Depression

Many community mental health centers have implemented peer treatment models that employ recovered former clients as cost‐efficient adjunct providers. The effectiveness of these and other peer‐administered interventions (PAIs) for treating depression symptoms has not been well‐established. The current study is a meta‐analysis of PAIs’ effects on depression symptoms. Twenty‐three eligible studies were identified. Study characteristics were coded by multiple raters, random‐effects models were used to compare mean effect sizes, and mixed‐effects models were used to test for moderation. PAIs produced significant pre‐post reductions in depression symptoms (d = .5043 [95 % CI .3675–.6412]). In direct comparisons, PAIs performed as well as non‐peer‐administered interventions (.0848 [?.1455–.3151]), and significantly better than no‐treatment conditions (.2011 [.0104–.3918]). PAIs that involved a professional in a secondary treatment role were significantly less effective than those that were purely peer‐administered, and educational/skills‐based PAIs produced better outcomes than those that were mainly supportive. Follow‐up data, when available, indicated that PAIs’ benefits were maintained. PAIs reduce depression symptoms and warrant further study. The clinical significance of PAIs’ benefits, and whether they are better suited as stand‐alone or adjunct treatments, remain to be established. Implications for the roles of mental health professionals are discussed.     

Internalizing symptomatology and academic achievement: Bi-directional prospective relations in adolescence

Prior research has documented negative, concurrent relations between internalizing symptomatology and academic achievement among adolescents. The present study provided the first rigorous, longitudinal examination of the bi-directional, prospective relations between adolescent internalizing symptomatology and academic achievement. One hundred and thirty adolescents reported depression and anxiety annually from 6th through 10th grades, and GPA records were obtained annually from schools. Results showed that (a) high depression and anxiety at the beginning of a school year predicted lower GPA during that school year, and (b) low GPA in any school year predicted higher depression and anxiety at the beginning of the following school year. These findings underscore the tight link between adolescent internalizing symptomatology and academic achievement.     

Perfectionistic strivings and perfectionistic concerns interact to predict negative emotionality: Support for the tripartite model of perfectionism in Canadian and Chinese university students

For most individuals, perfectionistic strivings and perfectionistic concerns coexist to varying degrees. While there is agreement that within-person combinations of perfectionistic strivings and perfectionistic concerns produce meaningful “subtypes”, the number and characterization of these within-person combinations is still debated. The two most prominent person-centered perfectionism models (the tripartite model and the 2 × 2 model) offer differing characterizations of how perfectionistic strivings effects perfectionistic concerns’ relationship with psychological outcomes. According to the 2 × 2 model, perfectionistic strivings buffers against the negative effects of perfectionistic concerns. The 2 × 2 model thus claims the most deleterious within-person combination of perfectionistic strivings and perfectionistic concerns is low strivings and high concerns. In contrast, according to the tripartite model, perfectionistic strivings exacerbates the maladaptive effects of perfectionistic concerns. The tripartite model thus claims the most maladaptive within-person combination of perfectionistic strivings and perfectionistic concerns is high strivings and high concerns. The present study tested these competing claims in a group of English speaking Canadians and a group of Mandarin speaking Chinese. Results support the tripartite model of perfectionism.     

Cognitions as mediators in the relationship between self-compassion and affect

Previous studies suggest that self-compassion is related to numerous facets of mental health, but the role of cognitions in this relationship remains unknown. To examine the mediating role of cognitions in the relationship between self-compassion and anxiety, depression, and life satisfaction when controlling for self-esteem in Japanese people, we conducted two studies. Study 1 (N = 231) examined the relationship between self-compassion and affect by modeling negative automatic thoughts as a mediator; Study 2 (N = 233) tested whether positive and negative automatic thoughts meditate this relationship. Results suggested that both self-compassion and self-esteem increased positive automatic thoughts and decreased trait anxiety, whereas only self-esteem increased life satisfaction and decreased depression directly. Positive automatic thoughts increased life satisfaction and decreased depression and trait anxiety, and positive automatic thoughts mediated the relationship between self-compassion and negative affect. These findings suggest that both positive and negative automatic thoughts mediate the relationship between self-compassion and affect in Japanese people.     

Validity of the German Test Anxiety Inventory (TAI‐G) in an Australian sample

Test anxiety (TA) is a prevalent issue among students that can result in deleterious consequences, such as underachievement. However, a contemporary measure that has been validated for use with Australian students seems to be lacking. This study, therefore, investigated the suitability of the German Test Anxiety Inventory (TAI‐G) for use with Australian university students. While the original TAI‐G contains 30 items and was designed to measure four factors (worry, emotionality, interference, and lack of confidence), differing factorial models have been supported in the literature using either the original or a shortened 17‐item version of the measure. These differing TAI‐G models were tested and compared in the current study via confirmatory factor analysis using 224 Australian university students. As expected, results supported the superior fit of the 17‐item four‐factor model. Additionally, the convergent validity of the measure was supported since measures of self‐esteem, self‐efficacy, and general anxiety were all found to correlate significantly with the TAI‐G in the hypothesised directions. Finally, the finding that all of the TAI‐G subscales had acceptably high reliabilities led to the conclusion that the 17‐item TAI‐G is a valid and reliable measure of TA in an Australian university population.     

Latent class analysis of anxiety and depressive symptoms of the Youth Self-Report in a general population sample of young adolescents

This study examined whether distinct groups of young adolescents with mainly anxiety or mainly depression could be identified in a general population sample. Latent class analysis was used on self-report ratings of DSM-IV symptoms of anxiety and depressive disorders, because it was hypothesized that these ratings provide a bigger chance to identify distinct groups than parent ratings of symptoms that are poorly associated with DSM-IV. Results from exploratory and confirmatory latent class analysis showed that only very small numbers of young adolescents had mainly anxiety or mainly depressive symptoms. Instead, a five-group model fitted the data best. These five groups contained young adolescents who either had a high, intermediate, or low probability to have comorbid symptoms of anxiety and depression. It was concluded that symptoms of DSM-IV anxiety and depressive disorders co-occur in young adolescents, and that latent class analysis on items that capture also severe symptoms like suicidal thoughts are needed to derive groups with specific comorbidity patterns in a general population sample.     

Depressive symptoms are associated with unrealistic negative predictions of future life events

This study examined the relationship between depressive symptoms and bias in the prediction of future life events. Responding to internet announcements, 153 participants varying widely in self-reported depression symptom severity estimated the probability of 40 events occurring over the succeeding 30 days. After the 30-day period, participants reported which events occurred. Optimistic/pessimistic biases were related to level of depressive symptoms. A non-significant optimistic bias characterized participants with low depressive symptoms whereas a significant pessimistic bias characterized participants with high depressive symptoms. Those reporting mild symptoms did not exhibit a systematic pessimistic or optimistic bias. General imprecision in predictions for undesirable events was associated with depressive symptoms. These findings suggest that depression is associated with pessimistic bias rather than accuracy in judgment.     

Behavioural inhibition, anxious symptoms, and depressive symptoms: a short-term prospective examination of a diathesis-stress model

The purpose of the current study was to examine the relationship between behavioural inhibition (BI) and anxious symptoms within a diathesis-stress framework, using a short-term prospective design. In addition, we examined whether BI acts as a specific vulnerability to anxious symptoms, or as a common vulnerability to both anxious and depressive symptoms. At time 1, 384 children in grades 3 through 6 completed self-report measures of BI, anxious symptoms, and depressive symptoms. Six weeks later, they completed self-report measures of hassles, anxious symptoms, and depressive symptoms. Results demonstrated that children with high BI who experienced high levels of hassles during the 6-week follow-up interval showed increases in anxious symptoms, but not depressive symptoms.     

Relation of interest and self-efficacy occupational congruence and career choice certainty

A sample of 2145 adults completed the Personal Globe Inventory (PGI) as well as indicating their occupational choice and the certainty of this choice. The PGI yielded interest and self-efficacy scores and these were used with the occupational choice to calculate a congruence score for interests and one for efficacy. The prediction of career certainty by each congruence measure and their interaction was examined using hierarchical regression. The results indicated that while both interest and efficacy congruence were related to career certainty, efficacy congruence did not add to prediction above that obtained using interests congruence alone, however there was a substantial interaction. The agreement of interest congruence and efficacy congruence was related to a strong positive relation between congruence and certainty; whereas low agreement between interest and efficacy congruence was related to a non-significant relation between congruence and certainty. The results demonstrate the need to focus on both interest and efficacy and their agreement in our assessments and interventions.