The legacy of the silver methods and the new anatomy of the basal forebrain: implications for neuropsychiatry and drug abuse

The first part of the paper highlights the remarkable legacy of the silver methods, with special emphasis on the travails and opportunities offered by the various Nauta methods and their modifications. When the tracer methods based on axoplasmic flow were introduced in the early 1970s, they were exploited on a backdrop of a basic anatomical framework, which had already been established through the tracing of the major CNS pathways by the aid of the silver methods, especially the widely used Nauta-Gygax methods and their modifications. Some of the silver methods that were developed in the late 1960s for the staining of degenerating boutons (e.g. the Fink-Heimer method and de Olmos cupric silver method) provided the necessary technical improvements that eventually led to a new and more productive way to look at the basal forebrain functional/anatomical organization; if it was not for the silver methods, we would in all likelihood still be promoting the nebulous notion of the substantia innominata rather than the concepts of the ventral striatopallidal system and the extended amygdala. The discovery and elaboration of these two macroanatomical systems symbolize what might deservedly be called the "new anatomy" of the basal forebrain. Following a review of the critical experiments which led to the development of the new anatomy of the basal forebrain, its topography in the human is reviewed in drawings of an abbreviated series of coronal sections. The discovery of the ventral striatopallidal system and its thalamic projection to the mediodorsal thalamus rather than to the ventral anterior-ventral lateral thalamic complex ushered in the idea of parallel cortico-subcortical reentrant circuits, which to a large extent has replaced the limbic system as a theoretical framework for neuropsychiatric disorders. The extended amygdala, which appears as a large ring formation around the internal capsule, is still controversial in some quarters, although it is slowly but surely making its way into the general neuroscience literature, especially in the field of addictive disorders. The ventral striatopallidal system and the extended amygdala are interwoven in a complex fashion with the basal nucleus of Meynert within the basal forebrain. Together, these three systems represent important output channels for so-called "limbic" forebrain regions, especially orbitomedial prefrontal cortex and medial temporal lobe structures, which are increasingly implicated in major neuropsychiatric disorders.     

Validity of a test of children's suggestibility for predicting responses to two interview situations differing in their degree of suggestiveness

In the present study the relative contributions of internal and external sources of variation in children's suggestibility in interrogative situations were examined. One hundred and eleven children (48 4- to 5-year-olds and 63 7- to 8-year-olds) were administered a suggestibility test (BTSS) and the most suggestible (N=36) and the least suggestible (N=36) children were randomly assigned to either an interview condition containing several suggestive techniques or to one containing only suggestive questions. The effects of internal sources of variation in suggestibility were compared with the effects of the interview styles on the children's answers. The former did influence the children, but the external sources of variation in suggestibility had a stronger impact. Influences of cognitive, developmental factors could be found, but not when abuse-related questions were asked and high pressured interview methods were used. These findings indicate that individual assessment of suggestibility can be of some assistance when interviewing children, but diminishing suggestive influences in interrogations must be given priority.     

Divorce Terminable and Interterminable: A Psychoanalytic and Interdisciplinary Approach

Psychoanalytic therapy of divorce studies positive and negative aspects of couples' bonds, focusing on the guilt and narcissistic wounds of the multiple losses. Interactionally structured aspects of identity are especially difficult to mourn in the interminable divorces where separation is incomplete. A case demonstrates work with families to transform negative links, often including consultation with the legal system and work with the children.     

Inferential Intensionality

The paper is a study of properties of quasi-consequence operation which is a key notion of the so-called inferential approach in the theory of sentential calculi established in [5]. The principal motivation behind the quasi-consequence, q-consequence for short, stems from the mathematical practice which treats some auxiliary assumptions as mere hypotheses rather than axioms and their further occurrence in place of conclusions may be justified or not. The main semantic feature of the q-consequence reflecting the idea is that its rules lead from the non-rejected assumptions to the accepted conclusions.First, we focus on the syntactic features of the framework and present the q-consequence as related to the notion of proof. Such a presentation uncovers the reasons for which the adjective inferential is used to characterize the approach and, possibly, the term inference operation replaces q-consequence. It also shows that the inferential approach is a generalisation of the Tarski setting and, therefore, it may potentially absorb several concepts from the theory of sentential calculi, cf. [10]. However, as some concrete applications show, see e.g.[4], the new approach opens perspectives for further exploration.The main part of the paper is devoted to some notions absent, in Tarski approach. We show that for a given q-consequence operation W instead of one W-equivalence established by the properties of W we may consider two congruence relations. For one of them the current name is kept preserved and for the other the term W-equality is adopted. While the two relations coincide for any W which is a consequence operation, for an arbitrary W the inferential equality and the inferential equivalence may differ. Further to this we introduce the concepts of inferential extensionality and intensionality for q-consequence operations and connectives. Some general results obtained in Section 2 sufficiently confirm the importance of these notions. To complete a view, in Section 4 we apply the new intensionality-extensionality distinction to inferential extensions of a version of the ukasiewicz four valued modal logic.     

Rigidity in Parent—Child Interactions and the Development of Externalizing and Internalizing Behavior in Early Childhood

Behavioral rigidity is a common feature of many psychopathologies, yet the association between rigidity and the development of childhood psychopathology has not been studied. State space grids (a dynamic systems [DS] method) were used to examine the relation between rigidity in parent-child interactions and childhood externalizing and internalizing problems. High-risk kindergarten children (n = 240) and their parents were observed for 2 hr engaging in a variety of tasks that were expected to elicit a range of affect. State space grid analysis of the observational data revealed an association between rigidity in parent-child interactions and child externalizing behavior problems in the fall and spring of kindergarten and 1st grade, and with growth in those problems over time. Rigidity was associated with concurrent levels and with chronic high-level internalizing problems. Strengths and limitations of the new DS methodology in relation to understanding child psychopathology are discussed.     

Influence of vestibular signals on bodily self-consciousness: Different sensory weighting strategies based on visual dependency

Previous studies showed that the vestibular system is crucial for multisensory integration, however, its contribution to bodily self-consciousness more specifically on full-body illusions is not well understood. Thus, the current study examined the role of visuo-vestibular conflict on a full-body illusion (FBI) experiment that was induced during a supine body position. In a mixed design experiment, 56 participants underwent through a full-body illusion protocol. During the experiment, half of the participants received synchronous visuo-tactile stimulation, and the other half received asynchronous visuo-tactile stimulation, while their physical body was lying in a supine position, but the virtual body was standing. Additionally, the contribution of individual sensory weighting strategies was investigated via the Rod and Frame task (RFT), which was applied both before (pre-FBI standing and pre-FBI supine) and after the full-body illusion (post-FBI supine) protocol. Subjective reports of the participants confirmed previous findings suggesting that there was a significant increase in ownership over a virtual body during synchronous visuo-tactile stimulation. Additionally, further categorization of participants based on their visual dependency (by RFT) showed that those participants who rely more on visual information (visual field dependents) perceived the full-body illusion more strongly than non-visual field dependents during the synchronous visuo-tactile stimulation condition. Further analysis provided not only a quantitative demonstration of full-body illusion but also revealed changes in perceived self-orientation based on their field dependency. Altogether, findings of the current study make further contributions to our understanding of the vestibular system and brought new insight for individual sensory weighting strategies during a full-body illusion.     

Face Recognition Depends on Specialized Mechanisms Tuned to View-Invariant Facial Features: Insights from Deep Neural Networks Optimized for Face or Object Recognition

Face recognition is a computationally challenging classification task. Deep convolutional neural networks (DCNNs) are brain-inspired algorithms that have recently reached human-level performance in face and object recognition. However, it is not clear to what extent DCNNs generate a human-like representation of face identity. We have recently revealed a subset of facial features that are used by humans for face recognition. This enables us now to ask whether DCNNs rely on the same facial information and whether this human-like representation depends on a system that is optimized for face identification. In the current study, we examined the representation of DCNNs of faces that differ in features that are critical or non-critical for human face recognition. Our findings show that DCNNs optimized for face identification are tuned to the same facial features used by humans for face recognition. Sensitivity to these features was highly correlated with performance of the DCNN on a benchmark face recognition task. Moreover, sensitivity to these features and a view-invariant face representation emerged at higher layers of a DCNN optimized for face recognition but not for object recognition. This finding parallels the division to a face and an object system in high-level visual cortex. Taken together, these findings validate human perceptual models of face recognition, enable us to use DCNNs to test predictions about human face and object recognition as well as contribute to the interpretability of DCNNs.     

The Social Ecology of Parental Monitoring: Parent–Child Dynamics in a High‐Risk Peruvian Neighborhood

While parental monitoring is understood to protect adolescents from engaging in risk behaviors, little is known about how the family dynamics involved in parental monitoring differ across sociocultural contexts. We sought to gain an in‐depth understanding of parent–child relationship dynamics and parental knowledge of adolescents’ activities in an urban Peruvian neighborhood with high levels of crime and adolescent substance use. We conducted 15 in‐depth interviews and two focus groups with adolescents and 12 in‐depth interviews with mothers sampled from a secondary school in Callao, Peru. Our findings emphasize the importance of parent–child confianza (trust) as a foundation for parental awareness of adolescents’ lives and activities. Participants in our sample characterized confianza as encouraging adolescent disclosure and shaping how parental solicitation and rules were interpreted by adolescents. Participants described how confianza was rooted in features of the parent–child relationship, including shared parent–child time, parental affection, adolescent perceptions of parents’ ability to give good advice, and awareness of how parents would react to delicate topics. Participants linked these family dynamics, in turn, to economic hardship, parental feelings of sacrifice and stress, perceptions of neighborhood risk, and gender norms limiting fathers’ involvement in caregiving. Results have implications for the planning and adaptation of family‐based prevention programs for use in high‐risk contexts in Latin America.     

Churches in solidarity with the divided Korean Peninsula

This article explores God’s mission of reconciliation through the ecumenical efforts for peace, reconciliation, and reunification on the Korean Peninsula. It consists of three parts. The first section explores reconciliation as a means of overcoming the division system in Korea. The second section offers reconciliation as a peace process in the Korean context. The third section highlights the engagement in the reconciliation as a spiritual journey from the World Council of Churches’ global prayer campaign, which is a Christian pathway toward a peace system in the Korean Peninsula. In particular, this article demonstrates that prayer is not a strategy in our work of advocacy but a spiritual mandate and movement toward peace and justice cultivating reconciliation.     

Interventions for children and adolescents who stutter: A systematic review,meta-analysis,and evidence map

PurposeThis systematic review critically appraises and maps the evidence for stuttering interventions in childhood and adolescence. We examine the effectiveness of speech-focused treatments, the efficacy of alternative treatment delivery methods and identify gaps in the research evidence.MethodsNine electronic databases and three clinical trial registries were searched for systematic reviews, randomised controlled trials (RCTs) and studies that applied an intervention with children (2–18 years) who stutter. Pharmacological interventions were excluded. Primary outcomes were a measure of stuttering severity and quality assessments were conducted on all included studies.ResultsEight RCTs met inclusion criteria and were analysed. Intervention approaches included direct (i.e. Lidcombe Program; LP) and indirect treatments (e.g. Demands and Capacities Model; DCM). All studies had moderate risk of bias. Treatment delivery methods included individual face-to-face, telehealth and group-based therapy. Both LP and DCM approaches were effective in reducing stuttering in preschool aged children. LP had the highest level of evidence (pooled effect size=-3.8, CI -7.3 to -0.3 for LP). There was no high-level evidence for interventions with school-aged children or adolescents. Alternative methods of delivery were as effective as individual face-to-face intervention.ConclusionThe findings of this systematic review and evidence mapping are useful for clinicians, researchers and service providers seeking to understand the existing research to support the advancement of interventions for children and adolescence who stutter. Findings could be used to inform further research and support clinical decision-making.