Hemispheric differences in the time-course of semantic priming processes: evidence from event-related potentials (ERPs)

To investigate hemispheric differences in the timing of word priming, the modulation of event-related potentials by semantic word relationships was examined in each cerebral hemisphere. Primes and targets, either categorically (silk-wool) or associatively (needle-sewing) related, were presented to the left or right visual field in a go/no-go lexical decision task. The results revealed significant reaction-time and physiological differences in both visual fields only for associatively related word pairs, but an electrophysiological difference also tended to reach significance for categorically related words when presented in the left visual field. ERP waveforms showed a different time-course of associative priming effects according to the field of presentation. In the right visual field/left hemisphere, both N400 and Late Positive Component (LPC/P600) were modulated by semantic relatedness, while only a late effect was present in the left visual field/ right hemisphere.     

Lateralized cognition: asymmetrical and complementary strategies of pigeons during discrimination of the "human concept"

This study was aimed at revealing which cognitive processes are lateralized in visual categorizations of "humans" by pigeons. To this end, pigeons were trained to categorize pictures of humans and then tested binocularly or monocularly (left or right eye) on the learned categorization and for transfer to novel exemplars (Experiment 1). Subsequent tests examined whether they relied on memorized features or on a conceptual strategy, using stimuli composed of new combinations of familiar and novel humans and backgrounds (Experiment 2), whether the hemispheres processed global or local information, using pictures with different levels of scrambling (Experiment 3), and whether they attended to configuration, using distorted human figures (Experiment 4). The results suggest that the left hemisphere employs a category strategy and concentrates on local features, while the right hemisphere uses an exemplar strategy and relies on configuration. These cognitive dichotomies of the cerebral hemispheres are largely shared by humans, suggesting that lateralized cognitive systems already defined the neural architecture of the common ancestor of birds and mammals.     

Developmental changes in the processing of hierarchical shapes continue into adolescence

The present study was designed to trace the normal development of local and global processing of hierarchical visual forms. We presented pairs of hierarchical shapes to children and adults and asked them to indicate whether the two shapes were the same or different at either the global or the local level. In Experiments 1 (6-year-olds, 10-year-olds, adults) and 2 (10-year-olds, 14-year-olds, adults), we presented stimuli centrally. All age groups responded faster on global trials than local trials (global precedence effect), but the bias was stronger in children and diminished to the adult level between 10 and 14 years of age. In Experiment 3 (10-year-olds, 14-year-olds, adults), we presented stimuli in the left or right visual field so that they were transmitted first to the contralateral hemisphere. All age groups responded faster on local trials when stimuli were presented in the right visual field (left hemisphere); reaction times on global trials were independent of visual field. The results of Experiment 3 suggest that by 10 years of age the hemispheres have adult-like specialization for the processing of hierarchical shapes, at least when attention is directed to the global versus local level. Nevertheless, their greater bias in Experiments 1 and 2 suggests that 10-year-olds are less able than adults to modulate attention to the output from local versus global channels-perhaps because they are less able to ignore distractors and perhaps because the cerebral hemispheres are less able to engage in parallel processing.     

Are there differential word length effects in the two visual fields?

This study examined whether differential word length effects in the two visual fields imply hemisphere-dependent modes of word recognition. Length was defined as the number of constituent characters of Chinese foreign names (Experiments 1 and 2), as the number of constituent morphemes of three-character words (Experiments 3 and 4), and as that of constituent words of phrases (Experiments 5 and 6). Two types of experimental tasks were adopted, one required linguistic judgments on overall items (Experiments 1, 3, and 5) and the other was target detection tasks performed on the same set of stimuli (Experiments 2, 4, and 6). Five of the six experiments failed to find any kind of interaction between length and visual field. An interaction was observed only for the detection of characters embedded in foreign names, that is, when lexical access is least involved in the task, suggesting that word recognition plays a minimum role in the phenomenon. Other observations suggested that modes of word recognition are more frequency-dependent than hemisphere-dependent, and that Chinese compound words and phrases, although hardly distinguishable, do behave differently.     

The bilingual Loch Ness Monster raises its non-asymmetric head again-or, why bother with such cumbersome notions as validity and reliability? Comments on Evans et al. (2000)

All of the experimental studies of the past 25 years combined and the meta-analyses of their findings have not advanced our knowledge of the lateralization of language in bilingual speakers one bit. We are left with a clutter of inherently uninterpretable contradictory results. Successive studies do not contribute a single brick to the edifice or a single piece to the puzzle-only more confusion. study is no exception. So far, there has been no demonstration of the validity of any experimental paradigm claiming to measure degree of language laterality in bilingual speakers. Experimentation is pointless unless the nature of what is alleged to be lateralized is clearly defined and the validity of the measures employed has been established. Because of the lack of validity of the paradigms used in bilingual laterality studies, experiments and meta-analyses of their findings cannot have any scientific significance. Like their predecessors, Evans et al. pay lip service to a number of methodological problems, but ignore their implications and simply carry on anyway. The authors ought to demonstrate, rather than assume, that degree of visual half-field advantage for single words corresponds to degree of lateralization of any component of language (even if only of words).     

Kinematic parameters of hand movement during a disparate bimanual movement task in children with unilateral Cerebral Palsy

Children with unilateral Cerebral Palsy (uCP) experience problems performing tasks requiring the coordinated use of both hands (bimanual coordination; BC). Additionally, some children with uCP display involuntary symmetrical activation of the opposing hand (mirrored movements). Measures, used to investigate therapy-related improvements focus on the functionality of the affected hand during unimanual or bimanual tasks. None however specifically address spatiotemporal integration of both hands. We explored the kinematics of hand movements during a bimanual task to identify parameters of BC. Thirty-seven children (aged 10.9 ± 2.6 years, 20 male) diagnosed with uCP participated. 3D kinematic motion analysis was performed during the task requiring opening of a box with their affected- (AH) or less-affected hand (LAH), and pressing a button inside with the opposite hand. Temporal and spatial components of data were extracted and related to measures of hand function and level of impairment. Total task duration was correlated with the Jebsen–Taylor Test of Hand Function in both conditions (either hand leading with the lid-opening). Spatial accuracy of the LAH when the box was opened with their AH was correlated with outcomes on the Children’s Hand Use Experience Questionnaire. Additionally, we found a subgroup of children displaying non-symmetrical movement interference associated with greater movement overlap when their affected hand opened the box. This subgroup also demonstrated decreased use of the affected hand during bimanual tasks. Further investigation of bimanual interference, which goes beyond small scaled symmetrical mirrored movements, is needed to consider its impact on bimanual task performance following early unilateral brain injury.     

Age-related Changes in Postural Sway During Sit-to-stand in Typical Children and Children with Cerebral Palsy

Objective: To assess age-related changes in postural sway during sit-to-stand (STS) in typical children (TC) and children with mild cerebral palsy (CP). Methods: Thirty-five TC and 23 children with mild CP were allocated in four different age groups: 5–6, 7–9, 10–12, and 13–15 years; they all performed STS movements over a force plate. Anterior-posterior and medial-lateral amplitude of center of pressure (CoP) displacement, area and velocity of CoP sway were analyzed and compared between the age groups for TC and children with CP. Results: TC at 5 to 6 years of age showed higher values of anterior-posterior CoP displacement and Area of CoP sway than at 10–12 years, during the stabilization phase. There were no age-related changes for CP. Conclusion: TC change their postural sway during the last STS phase over the years, reducing their body sway. Children with CP did not show age-related changes in sway during STS, reflecting a distinct rhythm of postural control development in this population.     

The temporally-integrated causality landscape: A theoretical framework for consciousness and meaning

Theoretical approaches to understanding consciousness have begun to converge upon areas of general agreement, yet substantive differences remain. Here, I introduce a new theoretical framework for the emergence of consciousness from the functional integration of the thalamocortical system: the Temporally-Integrated Causality Landscape (TICL). TICL presents a novel perspective which addresses important phenomenological characteristics of consciousness that other frameworks, such as IIT, do not. First, the TICL is based upon the observation that conscious experiences are temporally continuous, not discrete. Secondly, the TICL establishes a thalamocortical basis for the point-of-view. According to TICL, consciousness is composed of contents that arise from neuronal subsystems that have meaning from the point-of-view of the larger, integrated system in which they are nested. Meaningful contents emerge from the subsystems because they exhibit a level of temporally-integrated causality (TIC) that is distinguishable from that of the larger system.     

脑梗塞、脑出血病人外显与内隐记忆的实验研究

采用模糊字辨认、自由回忆和再认的方法分别测试脑梗塞、脑出血病人（实验组）与无脑部病变者（对照组）外显记忆和内隐记忆成绩。结果发现：实验组较对照组外显记忆降低，内隐记忆存在。提出病人其记忆功能呈外显记忆损害，内隐记忆保存的特点。这种记忆功能的双重性为此种病人记忆功能康复训练提供了新的实验证据。