THE EFFECTS OF FEEDBACK ON BLOOD PRESSURE DISCRIMINATION

Discrimination of blood pressure in the natural environment as a function of feedback was assessed. Seventeen normotensives screened for blood pressure lability were randomly assigned to two groups. These subjects were then asked to estimate their systolic and diastolic blood pressure values two times per day over a 4-week period. Feedback for accuracy of blood pressure discriminations was implemented across the two groups in a multiple baseline fashion, using a feedback withdrawal condition in Group I to assess maintenance effects over time. Results showed improvement in discrimination accuracy for subjects in both groups when feedback was used, and no decrement in performance over a 2-week period after feedback was removed for subjects in Group I. Discrimination of systolic pressures improved at a slightly faster rate than discrimination of diastolic pressures.     

Analogue drinking assessment: Sensation seeking and gender

This study assessed the relationship between sensation seeking measured as a trait variable and drinking behaviors observed unobtrusively in the laboratory. It was hypothesized that high-sensation-seeking subjects would consume more alcohol than low sensation seekers and experience greater enhancement of positive moods and body sensations associated with intoxication. Thirty female and 31 male subjects divided into high- and low-sensation-seeking subgroups participated in an ad libitum drinking situation with the manifest task of taste rating three types of vodka (actually 95% alcohol) or tonic. Dependent variables included beverage consumption, positive/negative mood states, body sensations, breath estimates of blood alcohol levels, and self-rated level of intoxication. All subjects reported feeling the effects of alcohol. Contrary to predictions, high-sensation-seeking subjects neither consumed more alcohol than their low-sensation-seeking counterparts nor drank more alcohol than tonic, Paradoxically, low-sensation-seeking women displayed significantly greater alcohol intake and intoxication than all other groups. Possible explanations for findings were considered as well as the necessity for multimethod assessments of both predictor (i.e., sensation seeking) and criterion (i.e., alcohol consumption) variables across time and situations.This research was supported by Grant Award AA04042-03 from the National Institute on Alcohol Abuse and Alcoholism to the first and third authors. Special Appreciation is expressed to Anne T. Patsiokas, Susan W. Altman, Victoria Molony-Sinnott, and Pamela J. Thompson for their invaluable assistance in collecting and analyzing the data.     

ACQUISITION,DISCRIMINATIVE STIMULUS CONTROL,AND RETENTION OF INCREASES/DECREASES IN BLOOD PRESSURE OF NORMOTENSIVE HUMAN SUBJECTS1

The aims of this study of 24 normotensive subjects were: to compare a free-operant with a discrete-trials training format; to determine the most effective training procedure by comparing instrumental conditioning with instructional set and a control; to see if both increases and decreases in blood pressure could be brought under discriminative control, and to examine the maintenance of acquired self-control of blood pressure. A 2 × 3 design was employed in which two trial formats (free operant and discrete trials) were factorially compared with three training conditions (instrumental conditioning, instructional set, and control). Instrumental conditioning was found superior to both the instructional set and control conditions in producing increases and decreases in mean diastolic blood pressure. The free-operant format led to a greater degree of learned BP control in that subjects were able to increase and decrease their blood pressure by 10% to 15% of basal value and to maintain the blood-pressure operant after contingent auditory feedback/reinforcement was removed. Training was discontinued when subjects in the other five groups failed to reach criterion after 10 consecutive acquisition sessions.     

The differences between cerebral dominance patterns in the speed and accuracy of information processing among university students

IntroductionThe subject of cerebral dominance has received great attention by researchers; however, there is a paucity of studies that have examined its relationship to information processing.ObjectiveThe current study aims to reveal the differences between the cerebral dominance patterns (left cerebral dominance, right cerebral dominance, integrated parallel cerebral dominance) in the speed and accuracy of information processing.MethodA sample of (182) volunteers university students, (mean age ± SD, 19.92 ± 2.76 years; range, 18–24 years; 68 male, 114 females). The Human Information processing survey was applied to the participants. Each subject was exposed to two elementary cognitive tasks (Stroop task and Eriksen flanker task). Each task included two experimental conditions: first, the congruent condition that reflects the automatic processing of information; second, the incongruent condition that reflects the controlled processing of information.ResultsThe results of the study revealed that there were no differences between the patterns of cerebral dominance in the speed and accuracy of information processing.ConclusionAlthough the relationship between cerebral dominance and information processing is not significant, we need more studies to examine this relationship in other samples and in other experimental conditions.     

The significance of blushing for fair- and dark-skinned people

Since blushing is difficult to detect in people with dark skin, their experience of blushing may differ fundamentally from people with fair skin. To investigate this issue, cheek temperature and forehead blood flow were measured in 16 Caucasians and 16 Indians during mental arithmetic and singing. Caucasians (particularly females) thought that they blushed more intensely than Indians, and also reported greater self-consciousness when singing. Vascular responses did not differ between groups. However, skin tone moderated the association between vascular responses and ratings of self-consciousness, blushing intensity, blushing propensity and fear of negative evaluation. These findings support the notion that the visibility of blushing influences the nature of emotions experienced in embarrassing social encounters.     

Does functional neuroimaging solve the questions of neurolinguistics?

Neurolinguistic research has been engaged in evaluating models of language using measures from brain structure and function, and/or in investigating brain structure and function with respect to language representation using proposed models of language. While the aphasiological strategy, which classifies aphasias based on performance modality and a few linguistic variables, has been the most stable, cognitive neurolinguistics has had less success in reliably associating more elaborately proposed levels and units of language models with brain structure. Functional imaging emerged at this stage of neurolinguistic research. In this review article, it is proposed that the often-inconsistent superfluity of outcomes arising from functional imaging studies of language awaits adjustment at both "ends" of the process: model and data. Assumptions that our current language models consistently and reliably represent implicit knowledge within human cerebral processing are in line for major revision; and the promise of functional brain imaging to reveal any such knowledge structures must incorporate stable correlates of the imaging signal as dependent variable.     

A cheap telemetric system for analyzing gait.

This study presents a technique for gait analysis, developed for the assessment of footfall timing and speed. The system in question consists of a transmitter, a receiver, a conductive walkway and a PC with the appropriate software.The technique was first tested for accuracy and repeatability with known signals, and was validated with a group of 20 healthy male adults (mean age = 34 years, S.D. = 5.5). The results thus obtained were similar to those reported in the literature for corresponding groups. Then, measurements on 10 children suffering from cerebral palsy (spastic hemiplegia) were performed. Gait analysis was carried out just before surgery and one year post-operatively. The results confirm the validity of the technique for measurements on orthopedic patients and its efficiency for functional evaluation of gait improvement after surgery.     

Left-side dominance for song discrimination in Bengalese finches (Lonchura striata var. domestica)

Male Bengalese finches are left-side dominant for the motor control of song in the sensorimotor nucleus (the high vocal center, or HVc) of the telencephalon. We examined whether perceptual discrimination of songs might also be lateralized in this species. Twelve male Bengalese finches were trained by operant conditioning to discriminate between a Bengalese finch song and a zebra finch song. Before training, the left HVc was lesioned in four birds and the right HVc was lesioned in four other birds. The remaining four birds were used as controls without surgery. Birds with a left HVc lesion required significantly more time to learn to discriminate between the two songs than did birds with a right HVc lesion or intact control birds. These results suggest that the left HVc is not only dominant for the motor control of song, but also for the perceptual discrimination of song. Accepted after revision: 11 September 2001 Electronic Publication     

降压达标治疗中的个体化原则与优化治疗

为了提高高血压患者的降压达标率、最大程度地降低靶器官损伤,一方面应强化生活方式的改变,包括戒烟限酒、低盐饮食、减轻体重和适量运动,另一方面,由于原发性高血压的发病是由多种复杂因素的不同组合引起,应根据不同个体的高血压发病机制及病因的差异,在指南的指导下,应用不同种类抗高血压药物(单用或联合用药),采用针对个体的优化治疗,才能更有效地使降压治疗达标。     

有偿献血HIV感染者的情绪障碍

考察有偿献血HIV感染者的情绪状况,探讨他们面临的艾滋病压力和对感染HIV的认知评价对其情绪的影响。方法：采用Beck抑郁量表、焦虑自评量表、艾滋病压力量表、认知评价量表作为测查工具,测查了185名有偿献血HIV感染者,并收集了人口学资料、症状资料和其它信息。结果：（1）92%的有偿献血HIV感染者有中、重度抑郁障碍,他们的焦虑程度高于神经衰弱者和焦虑症者;（2）艾滋病压力不仅通过认知评价而且会直接对情绪障碍产生影响;（3）认知评价在艾滋病压力和情绪障碍之间起部分中介作用。结论：有偿献血HIV感染者抑郁、焦虑情绪障碍严重,艾滋病压力和认知评价对情绪障碍的产生都有直接或间接的影响