Associations of transcranial doppler velocity,age, and gender with cognitive function in children with sickle cell anemia in Nigeria

Children with sickle cell anemia (SCA) have elevated cerebral blood velocity relative to healthy peers. The primary aim of this study was to evaluate the association between cerebral blood velocity, measured by transcranial Doppler (TCD) ultrasound, age, and gender with cognitive function in children with SCA in Nigeria. Eighty-three children (M_age = 9.10, SD = 1.90 years; 55% female) with SCA in Nigeria completed cognitive assessments and a TCD ultrasound. The association between TCD velocity and measures of perceptual reasoning (Raven’s Progressive Matrices), working memory (WISC-IV Digit Span), and executive planning (Tower of London, TOL) were assessed. Results showed that elevated TCD velocity significantly predicted lower scores on TOL Time Violations and Total Problem-Solving Time when controlling for BMI, hemoglobin level, and parent education, suggesting that TCD velocity is related to the efficiency of executive function. Further, age was negatively related to children’s performance on the Ravens Matrices and TOL Total Correct, and boys showed greater deficits on the TOL Total Correct relative to girls. Moderation analyses for gender showed that there was a conditional negative association between TCD velocity and Digit Span for boys, but not for girls. Findings suggest that children with SCA in Nigeria with elevated TCD velocity are at risk for deficits in efficiency of executive planning, and boys with elevated TCD velocity are particularly at increased risk for deficits in auditory working memory. Implications of this study are important for interventions to reduce cerebral blood velocity and the use of TCD in this population.     

教学设计中的成绩表现和心流体验:基于认知负荷视角

教学设计是为优化教学效果而形成的教学实施方案。为提高学习表现,认知负荷理论认为在组织教学设计时需考虑内、外认知负荷两大因素,但少有研究关注学生在学习过程中的体验。本研究通过单词复合性操纵内在负荷,通过呈现方式操纵外在负荷,探究两类负荷对心流体验及表现的影响。结果发现,内在负荷对心流及表现均有影响,外在负荷仅在低水平组表现出对心流及表现的影响,另外内外负荷在低水平组的表现上存在交互作用。结果表明,教学设计中的内在负荷是影响心流及表现的稳定因素,外在负荷不仅受知识水平影响,其对表现的有效性还受内在负荷的调节。     

Applying the extended theory of planned behaviour to predict Chinese people's non‐remunerated blood donation intention and behaviour: The roles of perceived risk and trust in blood collection agencies

Against the backdrop of critical clinical blood shortage in China in recent years, the present research extends the theory of planned behaviour by incorporating two constructs potentially of importance in influencing non‐remunerated blood donation behaviour, namely perceived risk and individual trust in blood collection agencies to predict Chinese people's non‐remunerated blood donation intention and behaviour. A survey was conducted to measure variables of the theory of planned behaviour, and other variables such as experience of non‐remunerated blood donation, perceived risk and individual trust in blood collection agencies. Data to assess non‐remunerated blood donation behaviour were collected via phone interviews. Results of the path analysis are as follows. Subjective norm, perceived behavioural control and individual trust in blood collection agencies are all positively associated with attitudes toward non‐remunerated blood donation, explaining 46.9% of the variance in this variable. Perceived risk is negatively associated with blood donation intention, while subjective norm and attitudes toward non‐remunerated blood donation are both positively associated with blood donation intention. Together, the three variables account for 28.4% of the variance in donation intention. Both having a positive association with non‐remunerated blood donation behaviour, the combination of blood donation intention and donation experience explains 42.8% of its variance.     

The ecumenical vision of Pope Francis: journeying together as fellow pilgrims − ‘the mystery of unity has already begun’

After reviewing some of the unique ecumenical steps taken by Pope Francis, this article examines briefly the three ecumenical paragraphs in Evangelii Gaudium. It presents them in the wider context of this post-synodal exhortation, of the ecumenical gestures and testimonies of Pope Francis, the ecumenical orientation of the Catholic Church and the ecumenical movement as such. It concludes with an outlook on a newly emerging ecumenical paradigm.     

神经质人格与大学生网络小说成瘾关系:叙事传输和沉浸感的中介作用

本研究以502名大学生为被试,探讨神经质人格与网络小说成瘾的关系以及叙事传输和沉浸感在其中的序列中介作用。结果发现:(1)网络小说成瘾与神经质人格、叙事传输和沉浸感之间均呈显著正相关;(2)神经质人格不仅可以直接影响网络小说成瘾,还可以通过叙事传输和沉浸感的中介作用对其产生影响,且该中介作用包含了两条路径——沉浸感的单独中介作用以及叙事传输-沉浸感的序列中介作用。这一结论有助于引导大学生健康阅读网络小说,预防成瘾。     

Dynamical structure of center-of-pressure trajectories with and without functional taping in children with cerebral palsy level I and II of GMFCS

Postural control during quiet standing was examined in typical children (TD) and children with cerebral palsy (CP) level I and II of GMFCS. The immediate effect on postural control of functional taping on the thighs was analyzed. We evaluated 43 TD, 17 CP children level I, and 10 CP children level II. Participants were evaluated in two conditions (with and without taping). The trajectories of the center of pressure (COP) were analyzed by means of conventional posturography (sway amplitude, sway-path-length) and dynamic posturography (degree of twisting-and-turning, sway regularity). Both CP groups showed larger sway amplitude than the TD while only the CP level II showed more regular COP trajectories with less twisting-and-turning. Functional taping didn’t affect sway amplitude or sway-path-length. TD children exhibited more twisting-and-turning with functional taping, whereas no effects on postural sway dynamics were observed in CP children. Functional taping doesn’t result in immediate changes in quiet stance in CP children, whereas in TD it resulted in faster sway corrections. Children level II invest more attention in postural control than level I, and TD. While quiet standing was more automatized in children level I than in level II, both CP groups showed a less stable balance than TD.     

Religion and the decision to donate organs: Exploring the potential role of religious leaders

The two‐step flow model of communication (Katz, 1957 ) suggests opinion leaders obtain critical information from the mass media and, in turn, communicate this information to interpersonal contacts such as friends, family and co‐workers. It is suggested that religious leaders (RLs) may serve as opinion leaders on the topic of organ donation by debunking donation myths, promoting donation during worship services, or communicating the benefit of donation to families faced with the opportunity to participate in living or cadaveric donation. The current study examined the personal knowledge, experiences, and willingness to communicate about organ donation in a sample of RLs (N = 59) in Rochester, New York. Structured interviews were conducted in summer and fall of 2009 with a random sample of RLs. Results indicate a disparity between RLs' expressed personal support for donation and their engagement in donor registration. Approximately one‐quarter of RLs have spoken about donation during a religious service and many indicate their knowledge is not sufficient to discuss organ donation in detail. Results elaborate on how RLs may be trained to serve as opinion leaders in the promotion of organ donation. Copyright © 2010 John Wiley & Sons, Ltd.     

抢救一例Rh阴性稀有血型危重孕妇的体会与思考

Rh阴性稀有血型危重患者的临床救治相当棘手。本文通过回顾对一名Rh阴性血型危重孕妇的临床救治经过,探讨了应急情况下Rh阴性血型危重患者的临床救治策略和采供血应急措施,建议我国尽快建立稀有血型血库和制定相关法律法规,为应急情况下抢救Rh阴性血型患者提供依据和保障。