镜像神经在药物心理渴求中的作用及机制

心理渴求是物质依赖者希望重新感受神经活性药物效应的渴望,其神经机制的早期影像研究,主要集中在前额皮质和奖赏中枢.镜像神经是新近发现的位于动作脑区,能理解、分析所观察动作的目的和性质,并通过内隐模拟,产生直接映射式的情绪和认知的神经.最新的研究发现尼古丁成瘾者在相关线索的刺激下,其镜像神经也能被激活.本研究旨在探索镜像神经参与相关线索下心理渴求形成的机制,为发展更可靠的依赖行为的生物学标记提供另一个重要目标,帮助人们更好地理解药物渴求形成的神经生物学基础与过程.     

基于预期理论的参照依赖

参照依赖是指个体基于某一参照点对得失价值进行判断:参照点之上,个体感受为收益,反之即为损失.参照依赖现象广泛存在于生活中的各种领域.当前,对参照依赖心理机制的解释主要有预期理论、后悔理论和三阶段参照点理论.参照依赖的影响因素主要包括经验、情绪状态、文化、目标和认知对象的特点等.未来的研究应主要集中于参照依赖的产生根源,深入探讨参照依赖的神经机制,加强动态参照点、多重参照点以及群体中参照依赖现象的研究.     

Examining the structure of emotional intelligence at the item level: New perspectives,new conclusions

Despite twenty years of research, many unknowns remain regarding the Mayer–Salovey (e.g., 1997) model of emotional intelligence (EI) and the validity of tests that have been designed to measure it. Evidence relevant to the internal structure of EI has come mainly from factor-analytic studies of the MSCEIT and the MEIS, utilising parcelled task scores rather than individual test items. This approach has several deficiencies: in addition to the loss of item-level information, it results in an insufficient number of observed variables per factor and an inability to separate structural sources of local item dependence (i.e., method variance) from construct-related variance. The present study (N=707) employed multidimensional item response modelling to investigate the dimensional structure of the MSCEIT, at the item level, for the first time. It is shown that item format and the specific choice of task explain far more of the variance in response patterns than does the hypothesised dimensional structure of EI, to the point that there is no empirical reason to prefer a higher-dimensional model of EI over a unidimensional model. It is argued that the advantage of an item-level perspective can be fundamental, rather than merely incremental.     

The Professor and the Saint

I review James E. Dittes' scholarship on St. Augustine through the perspective of my experiences as a student in his seminar on The `Theologies' of Freud and Jung, sponsored by the National Endowment for the Humanities. Throughout this review, I emphasize Dittes' personal engagement with Augustine, and note his unabashed introspection as a mode of theological reflection.     

初中生羞怯与手机依赖的关系:一个有调节的中介模型

为探讨初中生羞怯、疏离感、班级心理环境和手机依赖的关系,采用羞怯量表、青少年疏离感量表、班级心理环境量表和手机依赖指数量表对山东省两所学校的1077名初一至初三年级的学生进行调查。结果显示：（1）羞怯显著正向预测初中生手机依赖;（2）疏离感在初中生羞怯与手机依赖之间起完全中介作用;（3）班级心理环境对中介效应的后半段路径起调节作用,高班级心理环境会缓解疏离感对手机依赖的影响,但在极高疏离感水平下,高班级心理环境反而会加剧个体的手机依赖水平。研究有助于了解羞怯对手机依赖的复杂影响机制,对预防以及减少初中生手机依赖具有一定的现实意义。     

A behavioral economic analysis of concurrently available money and cigarettes.

In economic terms, consumption of a reinforcer is determined by its price and the availability and price of other reinforcers. This study examined the effects of response-requirement (i.e., price) manipulations on the self-administration of two concurrently available reinforcers. Six cigarette smokers participated in 4-hr sessions in which money and puffs on a cigarette were concurrently available according to fixed-ratio schedules of reinforcement. Once stable responding was obtained with both reinforcers available at Fixed Ratio 100, the response requirement for one reinforcer was systematically varied (Fixed Ratio 1,000 and 2,500), while the other reinforcer remained scheduled at Fixed Ratio 100. Increasing the fixed-ratio size for a reinforcer decreased its consumption, with a greater decrease occurring for monetary reinforcement. This finding was quantified in economic terms as own-price elasticity, with elasticity coefficients greater for money than cigarettes. The effects of fixed-ratio size on response output also differed across the two reinforcers. Although greater responding occurred for money at Fixed Ratio 100, increases in fixed-ratio size (for money) decreased responding for money, whereas the same increase in fixed-ratio size (for puffs) increased responding for puffs. Finally, increasing the fixed-ratio size for one reinforcer had little effect on consumption of the other concurrently available reinforcer. This finding was quantified as cross-price elasticity, with elasticity coefficients near 0.0 for most subjects, indicating little or no reinforcer interaction. The results indicate that the reinforcing effects of cigarettes and money in the setting studied here differed, and that the effects produced by changing the price of one reinforcer did not interact with the consumption of the other concurrently available reinforcer.     

心理戒毒实验研究

1问题以往对毒品依赖者的临床治疗,偏重于躯体依赖的药物戒治,实践表明,克服戒断反应并不困难。然而,戒断反应消除了,毒瘾却并没戒除,表现是：复吸率非常高──达98％。如此之高的复吸率引起我们的注意：反复吸毒到底是一个生理问题还是一个心理问题？吸毒者在反复吸毒过程中追求的是什么？由此,导向另一个更深层次的问题：“戒毒要戒掉什么？”我们就此问题进行了调查,调查对象包括广州、探圳等戒毒所收治的150名吸毒者。结果显示：（1）开始吸毒时有非常强烈的情绪体验,这种情绪体验的强烈程度和愉快程度远远超过性交的体验。随…     

Drug effects on fixed-interval responding with pause requirements for food presentation.

In pigeons performing under a multiple schedule of food presentation, low key-pecking rates (0.18 to 0.29 responses per second) were maintained during 3-min fixed-interval components by requiring a 4-, 5-, or 6-sec pause preceding the food-delivery response (tandem DRL), while higher rates (0.70 to 1.37 responses per second) were maintained in alternative fixed-interval components by requiring a pause of no more than 40 msec preceding the food-delivery response (tandem DRH). Thus, reinforcement density was equal but overall response rates markedly different in the two schedule components. Pentobarbital (3, 10 mg/kg) had effects on overall rates of responding consistent with a rate-dependency interpretation (low rates were increased while higher rates were decreased), but d-amphetamine (0.03 to 3 mg/kg) either failed to increase low overall rates in the tandem DRL components or increased them only slightly. Effects of both drugs on local responding within the fixed-intervals were always related in an orderly way to control response rate, but the extent of rate increases produced by d-amphetamine was modifed in some birds by pause requirements such that the drug increased comparable rates less when these occurred in the tandem DRL component than when they occurred in the tandem DRH components. Control rate is an important determinant of drug effects, independent DRH components. Control rate is an important determinant of drug effects, independent of reinforcement density maintaining rates, and independent of environmental influences, such as response-spacing requirements for food presentation, that can modify the extent of some drug-produced rate changes.     

A systematic review of definitions of motor vehicle headways in driver behaviour and performance studies

Headway is a safety measure commonly used to investigate driving behaviour and driver performance. Its purpose is to reflect the following distance or time between a leading and following vehicle in traffic. It is therefore associated with drivers’ response time, such as in braking or swerving, during safety critical events. In the literature, distance and time headway are defined in different ways, despite standard definitions in the traffic engineering literature, which prompted this systematic review of headway definitions across a range of study designs, in order to recommend approaches to improve the accuracy and reproducibility of headway definitions used in road safety contexts. PRISMA guidelines were followed to search four databases (EMBASE, COMPENDEX, SCOPUS and MEDLINE) for studies that reported on headways or discussed methodological approaches. The search and filtering of abstracts identified 110 articles for a qualitative synthesis. Four broad approaches to measuring headways were detected: studies using simulation, roadside external features, on-road features, and on-vehicle features. Studies were coded as to whether they included written explanation, mathematical statements, or pictorial depictions of headway. Only 49.6% of studies contextualised headway sufficiently for reproducibility. Reproducibility is crucial for accurate interpretation of research findings and comparisons across studies. It is recommended that headway definitions should a) exclude vehicle or parts of vehicle lengths, b) include reference points (e.g., bumper/axle/rear), c) have a consistent terminology, and d) include the accuracy of headway measuring devices to report the precision of a study’s findings.     

The effects of aerobic exercise on working memory in methamphetamine-dependent patients: Evidence from combined fNIRS and ERP

ObjectiveTo explore the effect of aerobic exercise on working memory according to exercise intensity in patients with methamphetamine (MA) dependence.DesignTwelve-week randomized controlled trial.MethodForty-five MA-dependent patients were divided randomly into three groups participating in 12-week moderate- and high-intensity aerobic exercise interventions and no intervention (control), respectively. Working memory performance was assessed using a 2-back task, and a combined functional near-infrared spectral imaging–event-related potential measure was used to identify spatial and temporal components of the neurofunctional underpinnings of this performance.ResultsHigh-intensity exercise significantly enhanced the discernment aspect of working memory. It also decreased N1 and P2 amplitudes, and increased neural activity in the left dorsolateral prefrontal cortex.ConclusionsThe findings of this study suggest that high-intensity aerobic exercise can enhance working memory and neural activity in MA-dependent patients, and thus that it may serve as an effective therapeutic tool for these patients.