Selective involvement of the auditory-verbal modality in an acquired communication disorder: Benefit from sign language therapy

A 39-year-old female suffered bitemporal infarctions and exhibited an unusual behavioral syndrome of muteness and impaired auditory comprehension, with milder aphasic deficits in reading and writing. The anatomic basis of this modality-selective communication disorder appeared to involve both peripheral perceptual and motor as well as “central” language mechanisms. The patient's ability to communicate was greatly aided by instruction in Amerind and Ameslan Sign Language, in which she learned more than 100 signs. Patients whose acquired language deficits spare modalities of input or output may be ideal candidates for sign language therapy.     

Concurrent validity of the WISC-R factor scores

This study investigated the efficacy of predicting academic achievement as measured by the Wide Range Achievement Test using the factor scores of the Wechsler Intelligence Scale for Children-Revised as potential predictors. Both instruments were administered to 200 school children referred for psychological evaluations. Factor scores for the WISC-R were computed according to equations provided by Gutkin (1978). These factor scores then were regressed in a stepwise manner on the Reading, Spelling, and Arithmetic standard scores from the Wide Range Achievement Test. Stepwise regressions also were performed using the traditional Verbal and Performance IQs as the potential predictors. A comparison was made between the results obtained by use of the factors or the more common scores. The results indicated that the Freedom From Distractibility factor score significantly aided in the prediction of Reading and Spelling achievement and was of primary importance in predicting Arithmetic achievement. When the stepwise results using the different scores were contrasted, the factor scores accounted for appreaciably more variance in Arithmetic than did the traditional Verbal and Performance IQs. Derived regression equations are reported along with a discussion of the interpretability of the Freedom From Distractibility factor.     

Blocking acquisition of the rabbit's nictitating membrane response to serial conditioned stimuli

Three experiments demonstrated that prior training with one stimulus (CS1) would block acquisition of the rabbit's nictitating membrane response (NMR) to another stimulus (CS2) which was more contiguous to the US during serial compound training (CS1-CS2-US). Specifically, the CS1-US interval was 800 msec, which produces only a modest rate of CR acquisition, while the CS2-US interval was 400 msec, which is an optimal value for the NMR preparation. Experiment 1 demonstrated blocking when CS1 overlapped CS2, and Experiment 3 demonstrated blocking when CS1 and CS2 were presented in a strictly sequential fashion. Experiment 2 showed that the magnitude of blocking in the serial compound was comparable to that obtained in a simultaneous compound in which both the CS1-US and CS2-US intervals were 800 msec, thus making CS2 less contiguous with the US than in the serial compound. Moreover, the level of responding to CS2 in all serial compound groups (blocking and control) was lower than in the simultaneous compound groups. The present findings provide further evidence that the associative consequences of CS-US contiguity can be highly attenuated by processes of attention or competition for associative strength.     

Hemiplegic writing in severe aphasia

Three patients with severe aphasia and right hemiplegia are described who could write to dictation with the right arm using a limb prosthesis though agraphic with the "intact" left hand. The phenomenon of "hemiplegic writing" is explained as an access to submerged or preprocessing levels in language and action structure, through the use of older proximal motor systems. This interpretation has implications for our understanding of language and brain function, as well as for approaches to the treatment of patients with severe language disorders.     

Written spelling deficit of Broca''s aphasics

The purpose of this study was to investigate the nature of the written spelling deficit manifested by Broca's aphasics. Four spelling tests were given to eight Broca's aphasic patients. Analysis of misspelling errors led the investigators to conclude that Broca's aphasics do not spell phonically, but rather adhere exclusively to a visual/orthographic strategy. Possible cognitive deficits underlying the spelling problem are identified. The written spelling deficit is related to other features of the syndrome of Broca's aphasia, and finally, speculations are offered concerning the neurological substrate of written spelling in Broca's aphasic patients.     

Voice onset time production and perception in apraxic subjects

This study explored the relationship between the perception and production of voice onset time (VOT) in apraxic subjects. Spectrograms of the words, “bees” and “peas” spoken by apraxic subjects were acoustically analyzed to obtain a measure of VOT. The subjects also identified the initial cognate (“b” or “p”) from synthetically generated speech spanning a voiced to voiceless time continuum. The results suggest that apraxic subjects have production as well as perceptual errors in the voicing feature but no significant relationship was found between the two measures.     

Inferential processing of context: Studies of cognitively impaired subjects

Language comprehension tasks involving pronoun coreference were administered to a group of demented patients, a group of patients with cardiac disease, and groups of normal elderly persons and young adults. Pronoun coreference was constrained by either lexical, syntactic, or contextual cues. No differences were found between old and young subjects for any task. While the demented patients were impaired on all tasks, the cardiac patients were specifically impaired in the inferential processing of context.     

Central auditory processing : III. The “cocktail party” effect and anterior temporal lobectomy

The capacity to selectively attend to only one of multiple, spatially separated, simultaneous sound sources—the “cocktail party” effect—was evaluated in normal subjects and in those with anterior temporal lobectomy using common environmental sounds. A significant deficit in this capacity was observed for those stimuli located on the side of space contralateral to the lobectomy, a finding consistent with the hypothesis that within each anterior temporal lobe is a mechanism that is normally capable of enhancing the perceptual salience of one acoustic stimulus on the opposite side of space, when other sound sources are present on that side. Damage to this mechanism also appears to be associated with a deficit of spatial localization for sounds contralateral to the lesion.