Animal Mind: Science,Philosophy, and Ethics

Although 20^th-century empiricists were agnostic about animal mind and consciousness, this was not the case for their historical ancestors – John Locke, David Hume, Jeremy Bentham, John Stuart Mill, and, of course, Charles Darwin and George John Romanes. Given the dominance of the Darwinian paradigm of evolutionary continuity, one would not expect belief in animal mind to disappear. That it did demonstrates that standard accounts of how scientific hypotheses are overturned – i.e., by empirical disconfirmation or by exposure of logical flaws – is inadequate. In fact, it can be demonstrated that belief in animal mind disappeared as a result of a change of values, a mechanism also apparent in the Scientific Revolution. The “valuational revolution” responsible for denying animal mind is examined in terms of the rise of Behaviorism and its flawed account of the historical inevitability of denying animal mentation. The effects of the denial of animal consciousness included profound moral implications for the major uses of animals in agriculture and scientific research. The latter is particularly notable for the denial of felt pain in animals. The rise of societal moral concern for animals, however, has driven the “reappropriation of common sense” about animal thought and feeling.     

PHILOSOPHERS OF INTELLECTUAL DISABILITY: A TAXONOMY

Abstract: This essay explores various roles that philosophers occupy in relation to intellectual disability. In examining how philosophers define their object of inquiry as experts and gatekeepers, it raises critical questions concerning the nature of philosophical discourse about intellectual disability. It then goes on to consider three alternate positions, the advocate or friend, the animal, and the "intellectually disabled," each of which points to new ways of philosophizing in the face of intellectual disability.     

Anticipating intentional actions: The effect of eye gaze direction on the judgment of head rotation

Using a representational momentum paradigm, this study investigated the hypothesis that judgments of how far another agent’s head has rotated are influenced by the perceived gaze direction of the head. Participants observed a video-clip of a face rotating 60° towards them starting from the left or right profile view. The gaze direction of the face was either congruent with, ahead of, or lagging behind the angle of rotation. Following this, two static faces, at varying angles of rotation with respect to the end-point angle of the face in the video-clip, were presented simultaneously. The task of the participants was to decide which of the two heads was at an angle best resembling the angle of the end-point of the moving face. The critical test condition consisted of one test face oriented at 10° before, and the other at 10° after the end-point. The ‘lagging behind’ gaze condition elicited a significant underestimation of the rotation compared to the ‘congruent’ and ‘ahead’ gaze conditions. Participants did not exhibit similar biases when judging the rotation of several non-face control stimuli with visual features that mimicked different aspects of gaze direction. The findings suggest that when the gaze direction of a perceived agent is incongruent with the direction of the agent’s head motion observers automatically utilise this discrepancy to adjust their inferences about the agent’s intended heading direction.     

The clinical utility of the auditory P300 latency subcomponent event-related potential in preclinical diagnosis of patients with mild cognitive impairment and Alzheimer’s disease

The present meta-analysis investigated the clinical utility of the auditory P300 latency event-related potential in differentiating patients with Alzheimer’s disease (AD), patients with mild cognitive impairment (MCI), and unaffected controls. Effect size estimates were computed from mean P300 latency measurements at midline electrodes between patients and unaffected controls using the random effects restricted maximum likelihood model. The effects of clinical and ERP/EEG methological variables were assessed in a moderator analysis. P300 latency was found to be significantly prolonged in patients with AD (and MCI) compared to unaffected controls. Shortened P300 latencies were observed when comparing patients with MCI to patients with AD. Clinically relevant differences in P300 latency effect sizes were associated with mean age, interstimulus interval, stimulus difference, target frequency, reference electrode, and sampling rate. The meta-analytic findings provide robust statistical evidence for the use of the auditory P300 latency subcomponent as a biological marker of prodromal AD.     

樟柳碱所致学习和记忆障碍动物模型的探讨

本实验采用水迷津法、步下法和步入法,用樟柳碱制备学习和记忆障碍的动物模型。结果表明,樟柳碱(10毫克/公斤)可使小鼠引起学习障碍,其表现为通过水迷津全程的时间延长,而且小鼠进入盲路的错误次数明显增多。樟柳碱(10毫克/公斤)可使小鼠引起记忆障碍,在樟柳碱的影响下,小鼠步下平台或步入暗箱的潜伏期明显缩短,并使它们的错误次数增多。本实验结果进一步表明,测定小鼠的记忆障碍,步入法似乎比步下法更为敏感。     

恐惧发生与预防的实验研究：──Ⅰ、强烈噪音下恐具行为的动物模型

通过不同方法对ＳＤ型大鼠分四组进行实验处理,观察比较大鼠的行为,发现：在突然的高强度噪音条件下,大鼠出现恐惧的行为反应;强刺激组大鼠恐惧行为较控制组明显增多,行为的唤醒适应能力异常,并存在显著的个体差异;噪音脱敏训练对提高大鼠在高强噪音条件下的应激能力、减少恐惧具有良好的促进作用;在脱敏训练中尤以逐渐递增噪音强度、刺激时间与平均分配实验日结合的方法效果最为显著。     

Automatic access of the meanings of ambiguous words in context: Some limitations of knowledge-based processing

Five experiments are described on the processing of ambiguous words in sentences. Two classes of ambiguous words (noun-noun and noun-verb) and two types of context (priming and nonpriming) were investigated using a variable stimulus onset asynchrony (SOA) priming paradigm. Noun-noun ambiguities have two semantically unrelated readings that are nouns (e.g., PEN, ORGAN); noun-verb ambiguities have both noun and verb readings that are unrelated (e.g., TIRE, WATCH). Priming contexts contain a word highly semantically or associatively related to one meaning of the ambiguous word; nonpriming contexts favor one meaning of the word through other types of information (e.g., syntactic or pragmatic). In nonpriming contexts, subjects consistently access multiple meanings of words and select one reading within 200 msec. Lexical priming differentially affects the processing of subsequent noun-noun and noun-verb ambiguities, yielding selective access of meaning only in the former case. The results suggest that meaning access is an automatic process which is unaffected by knowledge-based (“top-down”) processing. Whether selective or multiple access of meaning is observed largely depends on the structure of the ambiguous word, not the nature of the context.     

Exogenous testosterone and social experience each enhance the development of aggressive behavior in Cyprinodon variegatus

The combined effects of testosterone and social experience from the time of hatching on development of aggressive behaviors in Cyprinodon variegatus were investigated. Social experience was defined as a rearing condition allowing visual, tactile, chemosensory, and auditory contact with zero, three, or 15 additional conspecifics. Behaviors were videotaped once weekly from 3 weeks to 4 months post-hatching, using the focal animal method, and an ethogram was constructed. At 3 months post-hatching, half the fish were injected once with testosterone propionate (2 μg/g b. w., i. p., vehicle-Ringer's solution) and the other half were injected with Ringer's isotonic saline solution. Testosteronetreated subjects showed significantly greater frequencies and durations of behaviors that may be related to aggression than did saline controls. Two weeks after the treatments, a round-robin tournament was conducted between testosterone- and saline-treated fish from each rearing condition. Testosterone-treated fish won significantly more encounters than did saline-treated subjects over all rearing conditions. Furthermore, significantly more aggressive acts were displayed by fish raised in the groups of 16 and the groups of four than did the Isolates. Although the number of aggressive acts exhibited by the group of 16 was greater than the group of four, the difference was not statistically significant.     

Ecofeminism: What One Needs to Know

Ecofeminism refers to feminist theory and activism informed by ecology. Ecofeminism is concerned with connections between the domination of women and the domination of nature. Although ecofeminism is a diverse movement, ecofeminist theorists share the presuppositions that social transformation is necessary for ecological survival, that intellectual transformation of dominant modes of thought must accompany social transformation, that nature teaches nondualistic and nonhierarchial systems of relation that are models for social transformation of values, and that human and cultural diversity are values in social transformation. Ecofeminist theology, ethics, and religious perspectives are particularly concerned with the integration of science and religion. Examples of religious or spiritual ecofeminisms are North American Christian ecofeminism, North American womanist Christian theology, neopagan Wiccan ecofeminism, Native American ecofeminism, and Third World ecofeminism.