Executive function outcomes of children with traumatic brain injury sustained before three years

Traumatic brain injury (TBI) is a common cause of disability in childhood. While the outcomes of TBI sustained in school years has been heavily researched, very little is known about the impact of TBI in infants and young children. The aim of this study was to investigate the impact of TBI on executive function (EF) in children who sustained a TBI before 3 years of age. A group of 55 children, 19 with a mild TBI, 16 children with a moderate-severe TBI, and 20 uninjured comparison children participated. The EF of children aged 3 to 6 years were compared using child-based measures of attentional control and information processing. Parents completed questionnaires rating their child's EF. Severity groups differed on the child-based EF measure of attentional control with children with TBI performing below the control group. There were no significant group differences for information processing or parent-rated EF. It appears that children who sustain a TBI before the age of 3 years display impairments in some areas of attentional control 3–4 years postinjury. The findings fit with the existing EF literature for older children.     

风险决策和跨期决策的过程比较：以确定效应和即刻效应为例

风险决策和跨期决策与人类生存发展密切相关, 且两类决策在理论发展、行为效应及神经基础等方面具有相似性。为检验二者是否具有共同过程机制, 本研究以风险决策中的确定效应和跨期决策中的即刻效应为例, 采用眼动追踪技术比较了它们的局部、整体过程及模型拟合。辅以贝叶斯因子分析实验数据表明：二者的主要过程特征均相似, 且更符合非折扣模型假设; 二者在加工复杂程度等少数特征上有所不同; 确定和即刻信息在加工方向等特征上存在特异性。这表明二者可能具有共同的核心决策规则：两类决策更可能遵循非折扣模型预期的简捷、启发式规则, 而不是折扣模型所假设的补偿性、基于选项规则。本研究为建立两类决策的共同解释框架做出了有益尝试, 并为决策比较研究方法提供新的方向。     

Visual aspects of centrally elicited attack behavior in the cat: “Patterned reflexes” associated with selection of and approach to a rat

It has been previously suggested that the electrical brain stimulation which elicits quiet-biting attack in the cat actively affects the way the central nervous system processes visual and tactile information concerned with the reflexes involved in the terminal aspects of attack. In order to examine the effects of brain stimulation on a nonterminal aspect of attack – the stimulated cat's selection of and approach to a rat – cats were implanted with attack-eliciting electrodes in both the lateral hypothalamus and the midbrain ventral tegmental area. These cats were then tested in an 8-ft-long cage, one end of which was divided into three, 2-ft-long parallel compartments, whose openings faced the end of the cage from which the cat commenced its approach. An anesthetized rat was placed at the back of one compartment, a bowl of food at the back of another compartment, and the third compartment contained no object. It was found in the first experiment that the attack elicited by nearly all electrodes was selectively directed at the rat. However, the success of the cat in finding the compartment containing the rat varied dramatically for different electrodes in the same cat. Further, these differences were stable and did not change as the cat gained experience with the task. The results suggested that the stimulation of different brain sites in the same cat differentially affected the visual neural mechanisms involved in guiding a cat to a rat. Previous studies have also suggested that the effects of brain stimulation which elicits quiet-biting attack are largely lateralized to the side of the brain stimulated. In order to determine if the effects of stimulation on the neural mechanisms mediating the visually guided approach of a cat to a rat were also lateralized, attempts were made in a second experiment to disrupt the visual input to one side of the brain by unilaterally transecting the optic tract. It was found that this manipulation interfered with the visually guided selective approach to a rat, if the cat was stimulated through hypothalamic or mid-brain electrodes ipsilateral to the optic tract transection, but not if the hypothalamic or midbrain stimulation was on the contralateral (visually intact) side of the brain. However, any final interpretation of the results was confounded by the finding in all of these cats of a complex syndrome of neglect of all contralateral sensory information.     

错误相关负波（ERN）在精神病理学研究中的应用

错误相关负波（error-related negativity, ERN）是由行为错误诱发的一种脑电波成分,最大峰值在错误反应之后的50ms左右,偶极子源定位于前扣带回（anterior cingulate cortex, ACC）附近。错误加工（error processing）的经典研究范式中出现的ERN成分可能反映了ACC具有错误检测、冲突监控、强化学习、情绪动机等功能。大量研究表明过度的和不足的错误相关脑活动（hyperactive and hypoactive error processing）可能分别与精神病理学的内化性和外化性障碍（internalizing and externalizing disorders）相关联。内化性和外化性障碍的内表型（endophenotype）的研究,还存在许多值得进一步探索的问题。     

Functional analysis and treatment of inappropriate sexual behavior

The results of a functional analysis showed that inappropriate sexual behaviors exhibited by a 9-year-old boy who had been diagnosed with traumatic brain injury were maintained by positive reinforcement in the form of social attention. An intervention consisting of functional communication training and extinction resulted in reduced levels of inappropriate sexual behaviors.     

自上而下注意控制的脑成像研究进展

自上而下的注意控制是调节人类各种认知活动的一种重要执行功能,本文从三个方面总结了该领域内脑成像研究的新进展：(1)自上而下注意控制的脑机制;(2)不同种类的注意控制脑机制的一致性;(3)自上而下的注意控制对其它皮层中神经活动的影响。     

Information seeking on Bayesian conditional probability problems: A fuzzy-trace theory account

Recently, the ‘heuristics and biases’ approach to the study of decision making has been criticized, with a call for better integrated theory. Three experiments stemming from fuzzy-trace theory addressed information seeking on probability problems, and the cognitive representation of hit-rates, base-rates, and the contrapositive. As predicted by the fuzzy-trace principle of ‘denominator neglect’, many subjects exhibited ‘conversion errors’, confusing the hit-rate, P(A|B), with the answer, P(B|A). These subjects sought base-rates less often than other subjects. On causal problems, more subjects correctly represented base-rates, sought base-rates more often, and produced more accurate estimates than on non-causal problems. Subjects tutored on the meaning of the hit-rate sought the base-rate more often, and were more accurate than control subjects. Results are explained by fuzzy-trace theory principles of gist extraction, fuzzy processing preference, denominator neglect, and output interference.     

自发性知觉经络反应中产生刺麻感和积极情绪的原因

自发性知觉经络反应(autonomous sensory meridian response,ASMR)是指在特定的视听刺激下,某些个体(ASMR敏感个体)在头皮后部、颈部乃至全身体验到一种令人极度愉快和放松的刺麻感的现象。其中,刺麻感的产生可能是个体大脑中负责感觉和肌肉运动的脑区高度激活引起的; 而与情绪和奖赏有关脑区的高度激活以及心率和呼吸频率的下降可能是产生愉快和放松感的重要原因。相比普通个体,ASMR敏感个体具有较高的神经质、共情特质、感觉受暗示性和特质正念。这可能说明ASMR敏感个体的感觉敏感性较高,情绪稳定性较弱,且比较关注自己身体的内外感受。这些个性特质可能导致ASMR敏感个体对某些视听刺激中所包含的一些感觉和情绪信息更加敏感,对其反应也更加强烈。目前,ASMR已经被用于抑郁,压力,失眠和慢性疼痛等的临床治疗以及商业广告之中。但ASMR可能会干扰个体的执行功能,在认知控制需求较高的情景下应尽量避免接触ASMR刺激。     

贝叶斯统计方法的应用与现状

贝叶斯统计方法是心理学数据分析的热门方法。研究全面论述贝叶斯方法在心理学领域的应用与方向。现阶段贝叶斯方法以模拟研究为主,应用方向为心理学研究常用的项目反应理论、认知诊断、计算机自适应、结构方程模型。同时,评述发现贝叶斯方法正逐步被国内心理学研究者所接受。最后,文章讨论了当下贝叶斯统计在心理学研究中应用的局限性及可能的原因,建议统计学者开发界面友好的贝叶斯软件,并在心理学课程中加入贝叶斯知识。     

人类工作记忆的某些神经影像研究

采用神经影像技术研究人类工作记忆的脑机理是目前一个十分活跃的研究领域。研究表明存在负责不同信息加工的工作记忆系统 ,如词语工作记忆、空间工作记忆等 ,其中词语工作记忆主要由大脑左半球参与 ,空间工作记忆主要由大脑右半球参与。前额叶在工作记忆中的作用相当复杂 ,包括对记忆信息的注意和抑制、管理、整合等功能。合理巧妙的实验设计、多种研究手段的综合应用必将使人类工作记忆的脑机理得到充分阐明。