B. F. Skinner and G. H. Mead: on biological science and social science.

Skinner's contributions to psychology provide a unique bridge between psychology conceptualized as a biological science and psychology conceptualized as a social science. Skinner focused on behavior as a naturally occurring biological phenomenon of interest in its own right, functionally related to surrounding events and, in particular (like phylogenesis), subject to selection by its consequences. This essentially biological orientation was further enhanced by Skinner's emphasis on the empirical foundations provided by laboratory-based experimental analyses of behavior, often with nonhuman subjects. Skinner's theoretical writings, however, also have affinity with the traditions of constructionist social science. The verbal behavior of humans is said to be subject, like other behavior, to functional analyses in terms of its environment, in this case its social context. Verbal behavior in turn makes it possible for us to relate to private events, a process that ultimately allows for the development of consciousness, which is thus said to be a social product. Such ideas make contact with aspects of G. H. Mead's social behaviorism and, perhaps of more contemporary impact in psychology, L. Vygotsky's general genetic law of cultural development. Failure to articulate both the biological and the social science aspects of Skinner's theoretical approach to psychology does a disservice to his unique contribution to a discipline that remains fragmented between two intellectual traditions.     

简论里贝特的意识理论

里贝特是人类意识和自由意志的实验研究领域的一个卓越的、先驱性的神经科学家。里贝特的意识研究工作涉及如下四个方面：（1）关于意识研究的认识论原则;（2）对意识现象本性的界定;（3）意识机制的时控理论;（4）对自由意志的阐释和有意识的心智场理论。里贝特的意识研究独树一帜,其时控理论具有坚实可信的实验证据,它从时间维度揭示了有意识的主观体验以及无意识的心智功能与神经活动之间的时间机制。     

Reasons for Actions and Desires

It is an assumption common to many theories of rationality that allpractical reasons are based on a person's given desires. I shall callany approach to practical reasons which accepts this assumption a `Humean approach'.In spite of many criticisms, the Humean approach has numerous followers who take it to be the natural and inevitable view of practical reason. I will develop an argument against the Humean view aimingto explain its appeal, as well as to expose its mistake. I focus on just one argument in favour of the Humean approach, which I believe can be constructed as the background idea of many Humean accounts: the argument from motivation.I first present the argument from motivation and explain why it seems so compelling. However, I then develop an equally compellingobjection to desire-based approaches to reason, showing that they cannot accommodate the justificatory role of reasons. I show that this objection suggests that at least one of the premises of the argument from motivation must be false. And, finally, I argue thatwe should reject the premise that claims that only desires can explain actions. This result is fatal for desire-based views of practical reason. My conclusion is that practical reasons should be based not on desires, but on values.     

优化乙肝治疗方案真实评价治疗效果

目前乙肝治疗比较混乱,给患者带来许多损失,优化乙肝治疗方案,是从患者病情出发,实施个体化治疗,目标是安全、有效、经济和适度,处于抗病毒最佳时机的患者可以考虑使用干扰素或拉米夫定;乙肝病毒携带者暂时禁止使用药物治疗;急性乙肝只给与基本治疗,待其自愈.实施优化方案,杜绝各种各样的商业广告;凡是尝试性治疗,一律按照新药临床验证程序进行,一律实行免费.治疗乙肝的疗效最终取决于持久、完全效应,不应局限在病毒阴转或肝功正常上.     

中、西医治疗慢性乙型肝炎现状的分析与思考

分析了中、西医肝病临床治疗慢性乙型肝炎的现状,着重探讨了中医药在防治乙肝中的优势和不足.指出多数医生存在对乙肝发病机制认识模糊、不能提供合理的治疗方案和研究方法欠科学等三个误区.倡导用循征医学方法对中医药防治乙肝的疗效进行评价.     

乙肝防治决策的基本点

我国现有乙肝现症感染者1亿多人,乙肝防治决策需要整个社会的参与,决策是否可以取得成效取决于以下几个基本点:决策的权威性;决策的科学性;决策的可行性。决策的前提是:预防为主,治疗为辅。     

人类情绪记忆的行为遗传学与神经遗传学研究进展述评

情绪记忆及其增强效应存在广泛的个体差异,这种个体差异可能有其神经与遗传基础。近来的行为遗传学与神经遗传学证实人类ADRA2B基因缺失突变以及BDNF Val66Met基因的多态性与情绪记忆增强及其神经机制的个体差异相联系。本文重点介绍与人类情绪记忆相关的这两种基因,梳理了行为与神经遗传学研究的最新进展,指出未来应关注更多候选基因,并重视多个脑区之间的交互作用;还应使用情绪面孔刺激探索BDNF Val66Met基因多态性对情绪记忆编码和提取的影响等。     

慢性乙肝治疗路线图和HBV DNA、HBeAg、HBsAg定量的监测意义

慢性乙型肝炎病毒感染呈世界分布并且引起不良结局,是极为严重的健康问题。慢性乙型肝炎治疗最重要的目标是长期抑制病毒以改善预后,防止出现肝硬化、肝衰竭和肝癌。目前,抗病毒药物主要有干扰素和口服核苷（酸）类似物,核苷（酸）类似物的缺点主要在于长期治疗中出现耐药。路线图概念被用于监测耐药预测疗效。HBV DNA定量水平被作为路线图较好的监测指标。由于血清转换率及清除率过低,HBeAg、HBsAg定量检测不适合用于路线图监测,但对于使用聚乙二醇干扰素的慢性乙肝患者,可作为预测治疗应答的指标。     

乙脑患儿血清神经元特异性烯醇化酶、S-100蛋白、髓鞘碱性蛋白测定及其临床意义

为了解流行性乙型脑炎（乙脑）患儿血清神经元特异性烯醇化酶（NSE）、S-100蛋白（S-100）、髓鞘碱性蛋白（MBP）含量变化及其临床意义,用酶联免疫吸附法检测100例乙脑患儿血清NSE、S-100、MBP含量变化。结果显示,乙脑组患儿血清NSE、S-100、MBP含量与对照组比较显著增高（P均〈0．01）,增高程度与病情严重程度相平行（P〈0．01）。因此,血清NSE、S-100、MBP含量测定对乙脑患儿脑损伤严重程度及临床预后判断有重要参考价值。     

捡了西瓜，就该丢掉芝麻吗——浅谈医源性Wernicke脑病

探讨医源性Wernicke脑病（WE）的病因、临床及磁共振图像特点,回顾性分析6例医源性WE病例。医源性WE病前均有禁食史,其临床表现多样。磁共振图像为中脑导水管周围T2WI及Flair高信号。大部分病例补充维生素B1后可好转。提示医源性禁食导致体内维生素B1耗竭是医源性WE的病因,及时补充维生素B1是预防及治疗本病的关键。