Is Theory of Mind Understanding Impaired in Males with Fragile X Syndrome?

Males with fragile X syndrome (FXS) have difficulties with social interaction and many show autistic features. This study examined whether the social deficits characteristic of FXS are associated with theory of mind difficulties. Two groups of boys with FXS participated: a group with few autistic features and a group with many autistic features. An intellectual disability control group also participated. In addition to using standard theory of mind tasks, new techniques were used that were able to separate out the various processing demands of the task (e.g., memory, inhibitory control). Overall, the findings indicate that both groups of boys with FXS have difficulty with theory of mind tasks compared to an intellectual disability control group. However, both groups with FXS also performed worse on comparison trials that required working memory but not theory of mind. Theory of mind difficulties are likely to be an important aspect of the FXS clinical profile, but are most likely the result from a more basic difficulty with working memory.     

Shoemaker on Phenomenal Content

Sydney Shoemaker has given a sophisticated theory of phenomenal content, motivated by the transparency of experience and by the possibility of spectrum inversion without illusion (1994, 2000, 2001, 2002). It centers on the idea that color experiences represent what he calls “appearance properties”. I consider the different sorts of appearance properties that Shoemaker has suggested might enter into phenomenal content – occurrent appearance properties, dispositional appearance properties, and higher-order dispositional appearance properties – and argue that none of them are plausibly represented by color experiences. I argue that Shoemaker's theory faces a dilemma – either it makes misperception too difficult, or it does not truly accommodate veridical spectrum inversion. I then examine some alternative Russellian theories of phenomenal content that might be consistent with Shoemaker's motivations, including a different sort of proposal recently suggested by Shoemaker (forthcoming). I argue that these views are also lacking, for similar reasons as the appearance property view. Finally, I conclude that in order for a representationalist theory to properly accommodate spectrum inversion without illusion, phenomenal content must include an indexical element. Such a view requires the adoption of a broadly Fregean theory of phenomenal content, according to which sameness of phenomenal character does not entail sameness in extension. What phenomenally identical experiences have in common is not what they represent, but how they represent.     

Cognitive Behavioral Treatment of Comorbid Anxiety Disorders and Social Difficulties in Children with High-Functioning Autism: A Case Report

A substantial proportion of children with high-functioning autism (HFA) or Asperger syndrome (AS) have one or more comorbid anxiety disorders. Because anxiety disorders exacerbate the social difficulties and other functional impairments caused by an autism spectrum disorder (ASD), there is a need for efficacious treatments to address the clinical needs of youth with this comorbid presentation. This article describes an evidence-based cognitive behavioral therapy (CBT) treatment manual enhanced to address the unique characteristics and clinical needs of children with ASD. A case study is presented in which CBT was utilized in the successful treatment of an 11-year-old girl with HFA. The intervention was effective in reducing anxiety and improving social and adaptive functioning. These findings suggest that an enhanced CBT approach may be a viable intervention for children with comorbid HFA and anxiety disorders that should be further evaluated.     

Backward masking: evidence of reduced subcortical amygdala engagement in autism

Recent data suggest that subthreshold presentation of emotional information is relayed to the amygdala along subcortical pathways. We examined the effect of backward masked neutral and anxious faces on the social decisions of a group of high functioning children with autism ages 7-13 years and matched controls. Participants were asked to select the friendliest of two faces, one of which was associated with the subthreshold (33 ms) presentation of an anxious face (A/N) and the other a subthreshold neutral face (N/N). Neutral paired faces were selected more often than A/N paired faces by both groups. However, children with autism selected significantly fewer N/N stimuli and more A/N stimuli than controls. These results suggest that the social choices of children with autism were influenced less by emotional information presented subconsciously and suggest a subcortical contribution to the social/emotional processing deficits observed in autism.     

自闭症谱系障碍儿童对面孔加工的同龄偏向效应

采用视觉追踪技术,探讨自闭症谱系障碍(autism spectrum disorders, ASD)儿童面孔加工的同龄偏向效应。实验1选取19名ASD儿童和23名生理年龄匹配的普通儿童(typically developing, TD)为被试,通过自由观看同龄和异龄中性面孔,探讨ASD儿童是否存在面孔加工的同龄偏向效应;实验2选取22名ASD儿童和生理年龄匹配的25名TD儿童,通过自由观看快乐、愤怒和恐惧面孔,探讨情绪对ASD儿童面孔加工同龄偏向的影响。结果发现,(1)ASD儿童对同龄中性面孔的注视时间显著大于异龄中性面孔;(2)ASD儿童在愤怒和恐惧情绪下对同龄面孔的注视时间显著大于异龄面孔,而在快乐情绪下同龄和异龄的注视时间则无显著差异。这表明ASD儿童对面孔的注视加工存在同龄偏向效应,且受情绪的影响。     

孕育生命受限胎儿的围产期预立照护计划

通过对国外孕育生命受限胎儿的围产期预立照护计划的研究现状进行文献综述,为我国围产期安宁疗护的发展提供参考。当发现胎儿生命受限时,围产期预立照护计划成为了抚慰家庭丧亲之痛和协助做出合理医疗决策的关键工具。纵观国内发展情况,我国围产期安宁疗护的发展具有市场需求大、国家重视、国外经验可借鉴等优势。但由于缺乏相关培训和宣传,照护团队的服务水平和推行相关预立照护计划的意识低、大众认知低等问题制约其发展。故建议加大教育和宣传力度,提高公众认知和医护人员相关能力,以保证我国围产期安宁疗护的稳健发展。

     

Having both hands on the steering wheel: Driving behaviour of white-collar workers with degenerative eye conditions

Because people in the United States are highly reliant on cars for transportation, individuals with restricted driving abilities face severe accessibility constraints in the labour market. Guided by the social exclusion framework, we used a qualitative approach to gain insights into the role of car driving and alternative commute modes in the lives of white-collar workers with degenerative eye conditions. The study participants gradually restricted their driving behaviour as the disease progressed. They also exhibited several types of commute solutions, which lent themselves to a variation in the experienced degree of exclusion (both between participants and within participants over time), with changes in vision state and available resources. Another aim of our study was to identify the motivations for driving behaviour. The results showed that while a desire to reduce the risk of an accident motivated the participants to stop driving, certain normative (for men) and practical considerations motivated participants to continue driving. While all of the participants eventually stopped driving due to vision decline, the decision to quit often occurred only after the participants experienced one or more car accidents. Workplace accessibility is a factor that hinders labour market participation of individuals with degenerative eye conditions and encourages individuals to engage in risky behaviour.     

A review of methods in the study of attention in autism

Atypical attention, while not a diagnostic feature, is common in individuals with autism spectrum disorders (ASD). The study of these atypicalities has recently gained in both quantity and quality, due in part to an increased focus on attentional atypicalities as one of the earliest signs of ASD in infancy. A range of attentional processes and components have been investigated, and the methods used are varied, from Posner-type paradigms, to the more recent use of eye-movement recording and change-detection techniques. This methodological complexity is one factor in the production of conflicting evidence on the topic of attention in ASD. This review uses a focus on methodology to clarify the literature to date and provide a resource for researchers wishing to study attention in ASD. Other factors that have contributed to the current discrepancies in findings are discussed, particularly the role of individual and group differences within the population of people with ASD.     

Generic statements require little evidence for acceptance but have powerful implications

Generic statements (e.g., "Birds lay eggs") express generalizations about categories. In this paper, we hypothesized that there is a paradoxical asymmetry at the core of generic meaning, such that these sentences have extremely strong implications but require little evidence to be judged true. Four experiments confirmed the hypothesized asymmetry: Participants interpreted novel generics such as "Lorches have purple feathers" as referring to nearly all lorches, but they judged the same novel generics to be true given a wide range of prevalence levels (e.g., even when only 10% or 30% of lorches had purple feathers). A second hypothesis, also confirmed by the results, was that novel generic sentences about dangerous or distinctive properties would be more acceptable than generic sentences that were similar but did not have these connotations. In addition to clarifying important aspects of generics' meaning, these findings are applicable to a range of real-world processes such as stereotyping and political discourse.