Children Exposed to Intra-Familial Violence

Abstract

This investigation examined factors associated with attrition and retention within a sample of children with a history of intra-familial violence referred for outpatient services. The sample included 118 children, aged 4-17 years; of these 64% completed treatment, 20% did not engage in treatment and 16% terminated prematurely. Caregivers reporting high child-related parental distress (F(2, 32) = 3.9, p = 0.03) and high psychological distress (F(2, 70) = 3.3, p = 0.04) were less likely to engage in treatment. Making a child abuse report during assessment or treatment was not found to be associated with treatment engagement or attrition, χ² ₍₂₎= 0.4, p = 0.82. The implications of these findings for clinical practice and treatment outcome research are discussed.     

The Wisconsin Card Sorting Test and the cognitive assessment of prefrontal executive functions: A critical update

For over four decades the Wisconsin Card Sorting Test (WCST) has been one of the most distinctive tests of prefrontal function. Clinical research and recent brain imaging have brought into question the validity and specificity of this test as a marker of frontal dysfunction. Clinical studies with neurological patients have confirmed that, in its traditional form, the WCST fails to discriminate between frontal and non-frontal lesions. In addition, functional brain imaging studies show rapid and widespread activation across frontal and non-frontal brain regions during WCST performance. These studies suggest that the concept of an anatomically pure test of prefrontal function is not only empirically unattainable, but also theoretically inaccurate. The aim of the present review is to examine the causes of these criticisms and to resolve them by incorporating new methodological and conceptual advances in order to improve the construct validity of WCST scores and their relationship to prefrontal executive functions. We conclude that these objectives can be achieved by drawing on theory-guided experimental design, and on precise spatial and temporal sampling of brain activity, and then exemplify this using an integrative model of prefrontal function [i.e., Miller, E. K. (2000). The prefrontal cortex and cognitive control. Nature Reviews Neuroscience, 1, 59–65.] combined with the formal information theoretical approach to cognitive control [Koechlin, E., & Summerfield, C. (2007). An information theoretical approach to prefrontal executive function. Trends in Cognitive Sciences, 11, 229–235.].     

Participant Retention in the Parents Matter! Program: Strategies and Outcome

We present a discussion of the literature addressing retention of ethnic minority samples in longitudinal studies. In addition, we describe the retention procedures implemented in the Parents Matter! Program (PMP), a community-based sexual risk reduction intervention for African American families. Finally, the results of PMP's retention strategies are presented.     

Vagueness and Blurry Sets

This paper presents a new theory of vagueness, which is designed to retain the virtues of the fuzzy theory, while avoiding the problem of higher-order vagueness. The theory presented here accommodates the idea that for any statement S ₁ to the effect that Bob is bald is x true, for x in [0,1], there should be a further statement S ₂ which tells us how true S ₁ is, and so on – that is, it accommodates higher-order vagueness – without resorting to the claim that the metalanguage in which the semantics of vagueness is presented is itself vague, and without requiring us to abandon the idea that the logic – as opposed to the semantics – of vague discourse is classical. I model the extension of a vague predicate P as a blurry set, this being a function which assigns a degree of membership or degree function to each object o, where a degree function in turn assigns an element of [0,1] to each finite sequence of elements of [0,1]. The idea is that the assignment to the sequence 0.3,0.2, for example, represents the degree to which it is true to say that it is 0.2 true that o is P to degree 0.3. The philosophical merits of my theory are discussed in detail, and the theory is compared with other extensions and generalisations of fuzzy logic in the literature.     

自我面孔加工与注意——来自反眼跳的证据

作为一种具有重要生物学意义和社会性的视觉刺激,面孔比一般的视觉刺激更容易吸引注意.本研究以Eyelink 2000车载眼动仪为工具,在混合呈现的反眼跳任务中考察了32名大学生被试对自我面孔、恋人面孔和陌生面孔加工中的注意捕获和维持注意方面的特点.结果发现:在朝向眼跳任务中,自我面孔和恋人面孔的眼跳错误率显著低于异性陌生面孔,并且自我面孔和恋人面孔都表现出了保持注意的优势;而在反眼跳任务中,自我面孔、恋人面孔与陌生人面孔的反眼跳错误率和眼跳潜伏期没有显著差异.这一结果表明:自我面孔、恋人面孔与陌生面孔之间在高水平视觉特征上的差异没有达到影响反眼跳的最小可觉察差别量.因此,在反眼跳任务中面孔的优势效应掩盖了自我相关信息加工的优势,导致了自我面孔与陌生面孔没有表现出对注意捕获或保持注意上的差异.     

The Power of the Word May Reside in the Power of Affect

This commentary on Dan Shanahan’s, A New View of Language, Emotion and the Brain, basically agrees with an emotion-based view of the evolutionary and developmental basis of language acquisition. It provides a supplementary neuroscience perspective that is more deeply affective and epigenetic in the sense that all claims about neocortically-based language modules need to be tempered by the existing genetic evidence as well as the robust neuroscience evidence that the cortex resembles random-access-memory space, a tabula rasa upon which epigenetic and learning processes create functional networks. The transition from non-linguistic creatures to linguistic ones may have required the conjunction of social-affective brain mechanisms, morphological changes in the articulatory apparatus, an abundance of cross-modal cortical processing ability, and the initial urge to communicate in coordinate prosodic gestural and vocal ways, which may have been more poetic and musical than current propositional language. There may be no language instinct that is independent of these evolutionary pre-adaptations.

On the evolutionary origins of executive functions

In this paper it is proposed that the prefrontal lobe participates in two closely related but different executive function abilities: (1) "metacognitive executive functions": problem solving, planning, concept formation, strategy development and implementation, controlling attention, working memory, and the like; that is, executive functions as they are usually understood in contemporary neuroscience; and (2) "emotional/motivational executive functions": coordinating cognition and emotion/motivation (that is, fulfilling biological needs according to some existing conditions). The first one depends on the dorsolateral prefrontal areas, whereas the second one is associated with orbitofrontal and medial frontal areas. Current tests of executive functions basically tap the first ability (metacognitive). Solving everyday problems (functional application of executive functions), however, mostly requires the second ability (emotional/motivational); therefore, these tests have limited ecological validity. Contrary to the traditional points of view, recent evidence suggests that the human prefrontal lobe is similar to other primates and hominids. Other primates and hominids may possess the second (emotional executive functions) prefrontal ability, -but not the first (metacognitive executive functions) one. It is argued that metacognitive executive functions are significantly dependent on culture and cultural instruments. They probably are the result of the development and evolution of some "conceptualization instruments"; language (and written language as an extension of oral language) may represent the most important one. The second executive function ability (emotional/motivational) probably is the result of a biological evolution shared by other primates.     

AF-DX 116, a Presynaptic Muscarinic Receptor Antagonist, Potentiates the Effects of Glucose and Reverses the Effects of Insulin on Memory

Male Swiss mice were tested 24 h after training in a one-trial step-through inhibitory avoidance task. Low subeffective doses of -(+)-glucose (10 mg/kg, ip), but not its stereoisomer -(−)-glucose (30 mg/kg, ip), administered immediately after training, and AF-DX 116 (0.3 mg/kg, ip), a presynaptic muscarinic receptor antagonist, given 10 min after training, interact to improve retention. Insulin (8 IU/kg, ip) impaired retention when injected immediately after training, and the effects were reversed, in a dose-related manner, by AF-DX 116 (0.3, 1.0, or 3.0 mg/kg, ip) administered 10 min following insulin. Since AF-DX 116 possibly blocks autoreceptors mediating the inhibition of acetylcholine release from cholinergic nerve terminals, the present data support the view that changes in the central nervous system glucose availability, subsequent to modification of circulating glucose levels, influence the activity of central cholinergic mechanisms involved in memory storage of an inhibitory avoidance response in mice.     

A transfer of functions through derived arbitrary and nonarbitrary stimulus relations

During Experiments 1 and 2, subjects were trained in a series of related conditional discriminations in a matching-to-sample format (A1-B1, A1-C1 and A2-B2, A2-C2). A low-rate performance was then explicitly trained in the presence of B1, and a high-rate performance was explicitly trained in the presence of B2. The two types of schedule performance transferred to the C stimuli for all subjects in both experiments, in the absence of explicit reinforcement through equivalence (i.e., C1 = low rate and C2 = high rate). In Experiment 2, it was also shown that these discriminative functions transferred from the C1-C2 stimuli to two novel stimuli that were physically similar to the C stimuli (SC1 and SC2, respectively). For both these experiments, subjects demonstrated the predicted equivalence responding during matching-to-sample equivalence tests. In Experiments 3 and 4, the conditional discrimination training from the first two experiments was modified in that two further conditional discrimination tasks were trained (C1-D1 and C2-D2). However, for these tasks the D stimuli served only as positive comparisons, and ND1 and ND2 stimuli served as negative comparisons (i.e., C1 × ND1 and C2 × ND2). Subsequent to training, the negatively related stimuli (ND1 and ND2) did not become discriminative for the schedule performances explicitly trained in the presence of B1 and B2, respectively. Instead, the ND1 stimulus became discriminative for the schedule performance trained in the presence of B2, and ND2 became discriminative for the schedule performance trained in the presence of B1. All subjects from Experiment 4 showed that the novel stimulus SND1, which was physically similar to ND1, became discriminative for the same response pattern as that controlled by ND1. Similarly, SND2, which was physically similar to ND2, became discriminative for the same response pattern as that controlled by ND2. Subjects from both Experiments 3 and 4 also produced equivalence responding on matching-to-sample equivalence tests that corresponded perfectly to the derived performances shown on the transfer of discriminative control tests.     

Composition of brain oscillations and their functions in the maintenance of auditory,visual and audio–visual speech percepts: an exploratory study

In the present exploratory study based on 7 subjects, we examined the composition of magnetoencephalographic (MEG) brain oscillations induced by the presentation of an auditory, visual, and audio-visual stimulus (a talking face) using an oddball paradigm. The composition of brain oscillations were assessed here by analyzing the probability-classification of short-term MEG spectral patterns. The probability index for particular brain oscillations being elicited was dependent on the type and the modality of the sensory percept. The maintenance of the integrated audio-visual percept was accompanied by the unique composition of distributed brain oscillations typical of auditory and visual modality, and the contribution of brain oscillations characteristic for visual modality was dominant. Oscillations around 20 Hz were characteristic for the maintenance of integrated audio-visual percept. Identifying the actual composition of brain oscillations allowed us (1) to distinguish two subjectively/consciously identical mental percepts, and (2) to characterize the types of brain functions involved in the maintenance of the multi-sensory percept.