Multiple component agraphia in a patient with atypical cerebral dominance: an error analysis

A 52-year-old man with atypical cerebral dominance (left-handed for writing but mixed handedness for other tasks) suffered an extensive right hemisphere stroke, resulting in a combination of deficits that has not been previously reported. There were profound visual constructive and visual perceptual disturbances and a spatial agraphia, which were consistent with a nondominant hemisphere lesion. There was also a severe apraxic agraphia, which is typically associated with a dominant hemisphere lesion, but no other signs of dominant hemisphere dysfunction such as linguistic disturbance or limb-motor apraxia were present. This case serves to highlight the functional and anatomical relationship between handwriting and other forms of praxis; the various sources of error in letter formation; the need to be specific in labeling and describing agraphias ; and the role of a detailed analysis of writing errors in delineating the neuropsychological processes involved in handwriting.     

Stuttering and anxiety: The difference between stutterers and nonstutterers in verbal apprehension and physiologic arousal during the anticipation of speech and non-speech tasks

To test if stressful anticipation of speech situations is a factor in eliciting stuttering behavior, the difference between 24 stutterers and 24 nonstutterers in verbal apprehension and physiologic activity was studied before and during speech tasks (reading and conversation), and nonspeech tasks (motor and intelligence task).Results indicate that the difference between stutterers and nonstutterers mainly were restricted to anxiety ratings assessed after each task. Heart rate, vasomotor responses, and electrodermal activity recorded before and during speech tasks were higher compared with the physiologic activity before and during nonspeech tasks but, unexpectedly, this was also the case for nonstutterers. It is concluded that stuttering is not elicited by anxiety.     

The effect of semantic plausibility on sentence comprehension in aphasia

Tested were 50 aphasic patients (16 Broca's, 15 Wernicke's, 10 global, and 9 amnesic), 13 nonaphasic brain damaged patients, and 13 normal adults to evaluate the effect of semantic plausibility on sentence comprehension in active affirmative declarative sentences with a sentence-picture matching task. A plate of two pictures was provided for each stimulus sentence, and the subject was required to choose the picture corresponding to the sentence presented auditorily. Two types of sentences in terms of plausibility were prepared, i.e., probable sentences (P) describing common events in our daily life and improbable sentences (I) describing rare events. There were four kinds of combinations of a picture with the other to make a correct/(distractor) set, i.e., P/(P), P/(I), I/(P), and I/(I) constructions. The results indicated that probable sentences were more comprehensible than improbable sentences, and that the effect of semantic plausibility did not differ among aphasic types.     

Prognostic factors and classification issues in the treatment of secondary orgasmic dysfunction

The present study examined patient and problem characteristics as well as therapy process factors associated with success and failure in sex therapy for secondary orgasmic dysfunction. Ss were 23 married couples selected for emotional and marital stability; all wives were suffering from secondary orgasmic dysfunction. Sexual functioning and satisfaction were evaluated before and after 15 sessions of therapy. Ss also engaged in daily self-monitoring throughout the therapy program. Two criteria of therapeutic success were used: the couples' global sexual harmony and the females' frequency of orgasmic response in couple sexual activity. Higher pre-treatment masturbation rates by the female, as well as better awareness of her partner's sexual tastes and preferences, were related to poor therapeutic outcome. Greater pre-treatment enjoyment of non-genital caressing by the female as well as higher incidence of interpersonal orgasmic response in the past were associated with therapeutic success. The theoretical and research implications of the present findings are discussed.     

Stimulus intrusion on fixed-interval responding in the rat: The effects of electric shock intensity,temporal location,and response contingency

After a scalloped lever-press response pattern had developed under a fixed-interval food reinforcement schedule, a 15-sec electric shock was intruded for different groups of rats in the first, second, third, or fourth quarter of each inter-reinforcement interval. Shock intensity was systematically increased for individual rats over 70 sessions, from 0.05 to 1.6 mA. Additional between-groups comparisons involved response-dependent versus clock-dependent fixed-interval schedules, and response-dependent versus response-independent electric shock intrusion. Response rates within each fixed interval prior to, during, and following electric shock intrusion showed regular and reproducible increases and decreases under systematic application of the experimental variables. These results provide further evidence that the functions of a stimulus are determined in part by the parameters of intensity, response contingency, and temporal location with respect to reinforcement.     

Required relaxation: a method of inhibiting agitative-disruptive behavior of retardates

Institutionalized retardates frequently exhibit agitative-disruptive behavior. Recent experiments have shown that overcorrective training in specific types of behavior can inhibit inappropriate behavior. A procedure was developed in which overcorrective practice in relaxation was given to each of eight adult retardates for their disruptions. The agitated resident was required to spend a fixed period of time in relaxation in his own bed upon each occurrence of agitation. This overcorrective relaxation resulted in a rapid, enduring and almost complete reduction in such behavior as self-injury, threats, physical aggression, screaming, crying, cursing and tantrums. Ward attendants strongly preferred the required relaxation procedure to the time-out technique and other inhibition procedures they had used. The procedure appears to be about as effective as alternative techniques and to have the advantages of ease of implementation and acceptability by ward staff and retardates as a ‘reasonable’ reaction to agitation.     

The efficacy of progressive relaxation in systematic desensitization and a proposal for an alternative competitive response--the relaxation response.

The theoretical basis of systematic desensitization is reciprocal inhibition in which an alternative, competitive response to anxiety is conditioned to arousal-producing, phobic stimuli. Abbreviated training in progressive relaxation is believed to serve as a competitive response to anxiety by decreasing autonomic nervous system activity. However, physiologic studies of progressive relaxation have not substantiated that its practice is associated with such decreased autonomic activity. Consequently, the use of progressive relaxation has been a confounding factor in the determination of the function of reciprocal inhibition in systematic desensitization. To confirm and refine the theoretical constructs of reciprocal inhibition, it is necessary to test the effects of a response which is competitive to the anxiety response. Such a response may be the relaxation response which is characterized by physiologic changes consistent with decreased autonomic nervous system activity. Derived from meditational practices, techniques which ehcit the relaxation response incorporate the element of focused attention which has been implicated as a critical factor in systematic desensitization. Thus, the use of the relaxation response should be a more appropriate method than progressive relaxation if the therapeutic usefulness of systematic desensitization is indeed due to reciprocal inhibition.     

Influence of aging on recovery from aphasia in polyglots

We analyzed patterns of recovery, according to the rules of Pitres [1895, Revue de Medecine (Paris), 15, 873–899] and Ribot (1881, Les Maladies de la Memoire, Paris: Libraire Germer Baillere et Cie, pp. 146–147), in polyglot aphasics divided into subgroups by age. The rule of Ribot did not apply predictably for any age group. Pitres' rule clearly applied, but only for the nonelderly groups. Aging and its concomitant deterioration of recent memory seem to influence patterns of recovery from aphasia in polyglots.     

Deficits in temporal sequencing of verbal material: The effect of laterality of lesion

Temporal sequencing of verbal materials (digits, words, and geometric forms) presented in two sensory modalities (auditory and visual) to three groups of subjects (Broca's with left anterior lesions, patients with right hemisphere lesions, and normals) was examined. Each subject was asked to point to a set of stimuli in the same sequence as presented by the examiner. Results indicated that patients with left hemisphere lesions were more impaired on all tasks than the right hemisphere lesioned patients who, in turn, were impaired compared to normal controls. Response to auditory presentation was superior to response to visual presentation. Also, digits were the easiest for all groups, and words were easier than geometric forms. Of special interest was the finding which suggested that right hemisphere lesions are associated with impairment of verbal temporal sequencing under either auditory or visual presentation.